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Items: 1 to 20 of 456

1.

Integration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia.

Busche S, Ge B, Vidal R, Spinella JF, Saillour V, Richer C, Healy J, Chen SH, Droit A, Sinnett D, Pastinen T.

Cancer Res. 2013 Jul 15;73(14):4323-36. doi: 10.1158/0008-5472.CAN-12-4367. Epub 2013 May 30.

2.

Epigenetic landscape correlates with genetic subtype but does not predict outcome in childhood acute lymphoblastic leukemia.

Gabriel AS, Lafta FM, Schwalbe EC, Nakjang S, Cockell SJ, Iliasova A, Enshaei A, Schwab C, Rand V, Clifford SC, Kinsey SE, Mitchell CD, Vora A, Harrison CJ, Moorman AV, Strathdee G.

Epigenetics. 2015;10(8):717-26. doi: 10.1080/15592294.2015.1061174.

3.

CpG island methylator phenotype redefines the prognostic effect of t(12;21) in childhood acute lymphoblastic leukemia.

Roman-Gomez J, Jimenez-Velasco A, Agirre X, Castillejo JA, Navarro G, Calasanz MJ, Garate L, San Jose-Eneriz E, Cordeu L, Prosper F, Heiniger A, Torres A.

Clin Cancer Res. 2006 Aug 15;12(16):4845-50.

4.

The DNA methylome of pediatric acute lymphoblastic leukemia.

Davidsson J, Lilljebjörn H, Andersson A, Veerla S, Heldrup J, Behrendtz M, Fioretos T, Johansson B.

Hum Mol Genet. 2009 Nov 1;18(21):4054-65. doi: 10.1093/hmg/ddp354. Epub 2009 Aug 13.

PMID:
19679565
5.

A distinct DNA methylation signature defines pediatric pre-B cell acute lymphoblastic leukemia.

Wong NC, Ashley D, Chatterton Z, Parkinson-Bates M, Ng HK, Halemba MS, Kowalczyk A, Bedo J, Wang Q, Bell K, Algar E, Craig JM, Saffery R.

Epigenetics. 2012 Jun 1;7(6):535-41. doi: 10.4161/epi.20193. Epub 2012 Jun 1.

PMID:
22531296
6.

RUNX1 aberrations in ETV6/RUNX1-positive and ETV6/RUNX1-negative patients: its hemato-pathological and prognostic significance in a large cohort (619 cases) of ALL.

Pais AP, Amare Kadam PS, Raje GC, Banavali S, Parikh P, Kurkure P, Arora B, Gujral S, Kumar SA, Badrinath Y.

Pediatr Hematol Oncol. 2008 Sep;25(6):582-97. doi: 10.1080/08880010802237450.

PMID:
18728978
7.

The leukemia-specific fusion gene ETV6/RUNX1 perturbs distinct key biological functions primarily by gene repression.

Fuka G, Kauer M, Kofler R, Haas OA, Panzer-Grümayer R.

PLoS One. 2011;6(10):e26348. doi: 10.1371/journal.pone.0026348. Epub 2011 Oct 20.

8.

Large-scale CpG methylation analysis identifies novel candidate genes and reveals methylation hotspots in acute lymphoblastic leukemia.

Taylor KH, Pena-Hernandez KE, Davis JW, Arthur GL, Duff DJ, Shi H, Rahmatpanah FB, Sjahputera O, Caldwell CW.

Cancer Res. 2007 Mar 15;67(6):2617-25.

9.

hTERT promoter methylation and telomere length in childhood acute lymphoblastic leukemia: associations with immunophenotype and cytogenetic subgroup.

Borssén M, Cullman I, Norén-Nyström U, Sundström C, Porwit A, Forestier E, Roos G.

Exp Hematol. 2011 Dec;39(12):1144-51. doi: 10.1016/j.exphem.2011.08.014. Epub 2011 Sep 10.

PMID:
21914494
10.

Prevalence of ETV6-RUNX1 fusion gene in children with acute lymphoblastic leukemia in China.

Gao YJ, Zhu XH, Yang Y, Wu Y, Lu FJ, Zhai XW, Wang HS.

Cancer Genet Cytogenet. 2007 Oct 1;178(1):57-60.

PMID:
17889709
11.

Integrated methylome and transcriptome analysis reveals novel regulatory elements in pediatric acute lymphoblastic leukemia.

Almamun M, Levinson BT, van Swaay AC, Johnson NT, McKay SD, Arthur GL, Davis JW, Taylor KH.

Epigenetics. 2015;10(9):882-90. doi: 10.1080/15592294.2015.1078050.

12.

Epigenetic deregulation in pediatric acute lymphoblastic leukemia.

Chatterton Z, Morenos L, Mechinaud F, Ashley DM, Craig JM, Sexton-Oates A, Halemba MS, Parkinson-Bates M, Ng J, Morrison D, Carroll WL, Saffery R, Wong NC.

Epigenetics. 2014 Mar;9(3):459-67. doi: 10.4161/epi.27585. Epub 2014 Jan 6.

13.

Near-tetraploidy in childhood B-cell precursor acute lymphoblastic leukemia is a highly specific feature of ETV6/RUNX1-positive leukemic cases.

Attarbaschi A, Mann G, König M, Steiner M, Dworzak MN, Gadner H, Haas OA; Austrian Berlin-Frankfurt-Münster Cooperative Study Group.

Genes Chromosomes Cancer. 2006 Jun;45(6):608-11.

PMID:
16552772
14.

Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.

Ellinghaus E, Stanulla M, Richter G, Ellinghaus D, te Kronnie G, Cario G, Cazzaniga G, Horstmann M, Panzer Grümayer R, Cavé H, Trka J, Cinek O, Teigler-Schlegel A, ElSharawy A, Häsler R, Nebel A, Meissner B, Bartram T, Lescai F, Franceschi C, Giordan M, Nürnberg P, Heinzow B, Zimmermann M, Schreiber S, Schrappe M, Franke A.

Leukemia. 2012 May;26(5):902-9. doi: 10.1038/leu.2011.302. Epub 2011 Nov 11.

15.

Additional aberrations of the ETV6 and RUNX1 genes have no prognostic impact in 229 t(12;21)(p13;q22)-positive B-cell precursor acute lymphoblastic leukaemias treated according to the NOPHO-ALL-2000 protocol.

Barbany G, Andersen MK, Autio K, Borgström G, Franco LC, Golovleva I, Heim S, Heinonen K, Hovland R, Johansson B, Johannsson JH, Kjeldsen E, Nordgren A, Palmqvist L, Forestier E; Nordic Society of Paediatric Haematology and Oncology; Swedish Cytogenetic Leukaemia Study Group; NOPHO Leukaemia Cytogenetic Study Group.

Leuk Res. 2012 Jul;36(7):936-8. doi: 10.1016/j.leukres.2012.03.024. Epub 2012 Apr 21. No abstract available.

PMID:
22521551
16.

Analysis of ETV6/AML1 abnormalities in acute lymphoblastic leukaemia: incidence, alternative spliced forms and minimal residual disease value.

Codrington R, O'Connor HE, Jalali GR, Carrara P, Papaioannou M, Hart SM, Hoffbrand AV, Potter M, Prentice HG, Harrison CJ, Foroni L.

Br J Haematol. 2000 Dec;111(4):1071-9.

PMID:
11167742
17.
18.

DNA methylome analysis of acute lymphoblastic leukemia cells reveals stochastic de novo DNA methylation in CpG islands.

Wahlberg P, Lundmark A, Nordlund J, Busche S, Raine A, Tandre K, Rönnblom L, Sinnett D, Forestier E, Pastinen T, Lönnerholm G, Syvänen AC.

Epigenomics. 2016 Oct;8(10):1367-1387. Epub 2016 Aug 23.

19.

DNA methylation for subtype classification and prediction of treatment outcome in patients with childhood acute lymphoblastic leukemia.

Milani L, Lundmark A, Kiialainen A, Nordlund J, Flaegstad T, Forestier E, Heyman M, Jonmundsson G, Kanerva J, Schmiegelow K, Söderhäll S, Gustafsson MG, Lönnerholm G, Syvänen AC.

Blood. 2010 Feb 11;115(6):1214-25. doi: 10.1182/blood-2009-04-214668. Epub 2009 Nov 25.

20.

Epigenetic regulation of microRNAs in acute lymphoblastic leukemia.

Roman-Gomez J, Agirre X, Jiménez-Velasco A, Arqueros V, Vilas-Zornoza A, Rodriguez-Otero P, Martin-Subero I, Garate L, Cordeu L, San José-Eneriz E, Martin V, Castillejo JA, Bandrés E, Calasanz MJ, Siebert R, Heiniger A, Torres A, Prosper F.

J Clin Oncol. 2009 Mar 10;27(8):1316-22. doi: 10.1200/JCO.2008.19.3441. Epub 2009 Jan 21.

PMID:
19164206

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