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Items: 1 to 20 of 98

1.

Valosin-containing protein regulates the proteasome-mediated degradation of DNA-PKcs in glioma cells.

Jiang N, Shen Y, Fei X, Sheng K, Sun P, Qiu Y, Larner J, Cao L, Kong X, Mi J.

Cell Death Dis. 2013 May 30;4:e647. doi: 10.1038/cddis.2013.171.

2.

DNA-PKcs deficiency inhibits glioblastoma cell-derived angiogenesis after ionizing radiation.

Liu Y, Zhang L, Liu Y, Sun C, Zhang H, Miao G, Di CX, Zhou X, Zhou R, Wang Z.

J Cell Physiol. 2015 May;230(5):1094-103. doi: 10.1002/jcp.24841.

PMID:
25294801
3.

Knockdown of the DNA-dependent protein kinase catalytic subunit radiosensitizes glioma-initiating cells by inducing autophagy.

Zhuang W, Li B, Long L, Chen L, Huang Q, Liang ZQ.

Brain Res. 2011 Jan 31;1371:7-15. doi: 10.1016/j.brainres.2010.11.044. Epub 2010 Nov 23.

PMID:
21108935
4.

Serine/threonine protein phosphatase 6 modulates the radiation sensitivity of glioblastoma.

Shen Y, Wang Y, Sheng K, Fei X, Guo Q, Larner J, Kong X, Qiu Y, Mi J.

Cell Death Dis. 2011 Dec 8;2:e241. doi: 10.1038/cddis.2011.126.

5.

Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cells.

Olsen BB, Issinger OG, Guerra B.

Oncogene. 2010 Nov 11;29(45):6016-26. doi: 10.1038/onc.2010.337. Epub 2010 Aug 16.

PMID:
20711232
6.

Blockade of TGF-β signaling by the TGFβR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma.

Zhang M, Kleber S, Röhrich M, Timke C, Han N, Tuettenberg J, Martin-Villalba A, Debus J, Peschke P, Wirkner U, Lahn M, Huber PE.

Cancer Res. 2011 Dec 1;71(23):7155-67. doi: 10.1158/0008-5472.CAN-11-1212. Epub 2011 Oct 17.

7.

Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma.

Reichert S, Rödel C, Mirsch J, Harter PN, Tomicic MT, Mittelbronn M, Kaina B, Rödel F.

Radiother Oncol. 2011 Oct;101(1):51-8. doi: 10.1016/j.radonc.2011.06.037. Epub 2011 Aug 16.

PMID:
21852011
8.

The DNA-PK Inhibitor VX-984 Enhances the Radiosensitivity of Glioblastoma Cells Grown In Vitro and as Orthotopic Xenografts.

Timme CR, Rath BH, O'Neill JW, Camphausen K, Tofilon PJ.

Mol Cancer Ther. 2018 Jun;17(6):1207-1216. doi: 10.1158/1535-7163.MCT-17-1267. Epub 2018 Mar 16.

9.

Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response.

Chu PM, Chiou SH, Su TL, Lee YJ, Chen LH, Chen YW, Yen SH, Chen MT, Chen MH, Shih YH, Tu PH, Ma HI.

Radiat Oncol. 2011 Jan 19;6:7. doi: 10.1186/1748-717X-6-7.

10.

The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells.

Welsh JW, Mahadevan D, Ellsworth R, Cooke L, Bearss D, Stea B.

Radiat Oncol. 2009 Dec 22;4:69. doi: 10.1186/1748-717X-4-69.

11.

Gefitinib radiosensitizes stem-like glioma cells: inhibition of epidermal growth factor receptor-Akt-DNA-PK signaling, accompanied by inhibition of DNA double-strand break repair.

Kang KB, Zhu C, Wong YL, Gao Q, Ty A, Wong MC.

Int J Radiat Oncol Biol Phys. 2012 May 1;83(1):e43-52. doi: 10.1016/j.ijrobp.2011.11.037.

PMID:
22516386
12.

EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma.

Mukherjee B, McEllin B, Camacho CV, Tomimatsu N, Sirasanagandala S, Nannepaga S, Hatanpaa KJ, Mickey B, Madden C, Maher E, Boothman DA, Furnari F, Cavenee WK, Bachoo RM, Burma S.

Cancer Res. 2009 May 15;69(10):4252-9. doi: 10.1158/0008-5472.CAN-08-4853. Epub 2009 May 12.

13.

DNA-PKcs-dependent modulation of cellular radiosensitivity by a selective cyclooxygenase-2 inhibitor.

Kodym E, Kodym R, Chen BP, Chen DJ, Morotomi-Yano K, Choy H, Saha D.

Int J Radiat Oncol Biol Phys. 2007 Sep 1;69(1):187-93.

PMID:
17707272
14.

Valosin-containing protein phosphorylation at Ser784 in response to DNA damage.

Livingstone M, Ruan H, Weiner J, Clauser KR, Strack P, Jin S, Williams A, Greulich H, Gardner J, Venere M, Mochan TA, DiTullio RA Jr, Moravcevic K, Gorgoulis VG, Burkhardt A, Halazonetis TD.

Cancer Res. 2005 Sep 1;65(17):7533-40.

15.
16.

Glioblastoma cells deficient in DNA-dependent protein kinase are resistant to cell death.

Chen GG, Sin FL, Leung BC, Ng HK, Poon WS.

J Cell Physiol. 2005 Apr;203(1):127-32.

PMID:
15493013
17.

New role of osteopontin in DNA repair and impact on human glioblastoma radiosensitivity.

Henry A, Nokin MJ, Leroi N, Lallemand F, Lambert J, Goffart N, Roncarati P, Bianchi E, Peixoto P, Blomme A, Turtoi A, Peulen O, Habraken Y, Scholtes F, Martinive P, Delvenne P, Rogister B, Castronovo V, Bellahcène A.

Oncotarget. 2016 Sep 27;7(39):63708-63721. doi: 10.18632/oncotarget.11483.

18.

A novel histone deacetylase inhibitor TMU-35435 enhances etoposide cytotoxicity through the proteasomal degradation of DNA-PKcs in triple-negative breast cancer.

Wu YH, Hong CW, Wang YC, Huang WJ, Yeh YL, Wang BJ, Wang YJ, Chiu HW.

Cancer Lett. 2017 Aug 1;400:79-88. doi: 10.1016/j.canlet.2017.04.023. Epub 2017 Apr 25.

PMID:
28450160
19.

PI3K-Akt signaling regulates basal, but MAP-kinase signaling regulates radiation-induced XRCC1 expression in human tumor cells in vitro.

Toulany M, Dittmann K, Fehrenbacher B, Schaller M, Baumann M, Rodemann HP.

DNA Repair (Amst). 2008 Oct 1;7(10):1746-56. doi: 10.1016/j.dnarep.2008.06.017. Epub 2008 Aug 22.

PMID:
18678286
20.

Inhibition of the DNA-dependent protein kinase catalytic subunit radiosensitizes malignant glioma cells by inducing autophagy.

Daido S, Yamamoto A, Fujiwara K, Sawaya R, Kondo S, Kondo Y.

Cancer Res. 2005 May 15;65(10):4368-75.

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