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Items: 1 to 20 of 128

1.

Optineurin suppression causes neuronal cell death via NF-κB pathway.

Akizuki M, Yamashita H, Uemura K, Maruyama H, Kawakami H, Ito H, Takahashi R.

J Neurochem. 2013 Sep;126(6):699-704. doi: 10.1111/jnc.12326. Epub 2013 Jun 17.

2.

[Inflammatory mechanisms in amyotrophic lateral sclerosis].

Fujita K, Izumi Y, Kaji R.

Brain Nerve. 2012 Mar;64(3):273-8. Review. Japanese.

PMID:
22402721
3.

Nuclear factor κ B expression in patients with sporadic amyotrophic lateral sclerosis and hereditary amyotrophic lateral sclerosis with optineurin mutations.

Sako W, Ito H, Yoshida M, Koizumi H, Kamada M, Fujita K, Hashizume Y, Izumi Y, Kaji R.

Clin Neuropathol. 2012 Nov-Dec;31(6):418-23. doi: 10.5414/NP300493.

PMID:
22762947
4.

A novel optineurin truncating mutation and three glaucoma-associated missense variants in patients with familial amyotrophic lateral sclerosis in Germany.

Weishaupt JH, Waibel S, Birve A, Volk AE, Mayer B, Meyer T, Ludolph AC, Andersen PM.

Neurobiol Aging. 2013 May;34(5):1516.e9-15. doi: 10.1016/j.neurobiolaging.2012.09.007. Epub 2012 Oct 10.

PMID:
23062601
5.

Mutations of optineurin in amyotrophic lateral sclerosis.

Maruyama H, Morino H, Ito H, Izumi Y, Kato H, Watanabe Y, Kinoshita Y, Kamada M, Nodera H, Suzuki H, Komure O, Matsuura S, Kobatake K, Morimoto N, Abe K, Suzuki N, Aoki M, Kawata A, Hirai T, Kato T, Ogasawara K, Hirano A, Takumi T, Kusaka H, Hagiwara K, Kaji R, Kawakami H.

Nature. 2010 May 13;465(7295):223-6. doi: 10.1038/nature08971. Epub 2010 Apr 28.

PMID:
20428114
6.

[Identification of a new causative gene of amyotrophic lateral sclerosis; optineurin].

Maruyama H.

Rinsho Shinkeigaku. 2012;52(1):1-5. Review. Japanese.

PMID:
22260971
7.
8.

Optineurin insufficiency impairs IRF3 but not NF-κB activation in immune cells.

Munitic I, Giardino Torchia ML, Meena NP, Zhu G, Li CC, Ashwell JD.

J Immunol. 2013 Dec 15;191(12):6231-40. doi: 10.4049/jimmunol.1301696. Epub 2013 Nov 15.

9.

Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.

Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, Tokunaga F.

Nat Commun. 2016 Aug 24;7:12547. doi: 10.1038/ncomms12547.

10.

Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP-43-negative inclusions of C9ORF72-ALS.

Bury JJ, Highley JR, Cooper-Knock J, Goodall EF, Higginbottom A, McDermott CJ, Ince PG, Shaw PJ, Kirby J.

Neuropathology. 2016 Apr;36(2):125-34. doi: 10.1111/neup.12240. Epub 2015 Aug 24.

PMID:
26303227
11.

NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB.

Sudhakar C, Nagabhushana A, Jain N, Swarup G.

PLoS One. 2009;4(4):e5114. doi: 10.1371/journal.pone.0005114. Epub 2009 Apr 2.

12.

Depletion of optineurin in RGC-5 cells derived from retinal neurons causes apoptosis and reduces the secretion of neurotrophins.

Sippl C, Bosserhoff AK, Fischer D, Tamm ER.

Exp Eye Res. 2011 Nov;93(5):669-80. doi: 10.1016/j.exer.2011.08.011. Epub 2011 Aug 27.

PMID:
21896272
14.

Optineurin deficiency in mice is associated with increased sensitivity to Salmonella but does not affect proinflammatory NF-κB signaling.

Slowicka K, Vereecke L, Mc Guire C, Sze M, Maelfait J, Kolpe A, Saelens X, Beyaert R, van Loo G.

Eur J Immunol. 2016 Apr;46(4):971-80. doi: 10.1002/eji.201545863. Epub 2016 Jan 15.

15.

Honokiol inhibits TNF-alpha-stimulated NF-kappaB activation and NF-kappaB-regulated gene expression through suppression of IKK activation.

Tse AK, Wan CK, Shen XL, Yang M, Fong WF.

Biochem Pharmacol. 2005 Nov 15;70(10):1443-57. Epub 2005 Sep 21.

PMID:
16181613
16.

Defects in optineurin- and myosin VI-mediated cellular trafficking in amyotrophic lateral sclerosis.

Sundaramoorthy V, Walker AK, Tan V, Fifita JA, Mccann EP, Williams KL, Blair IP, Guillemin GJ, Farg MA, Atkin JD.

Hum Mol Genet. 2015 Jul 1;24(13):3830-46. doi: 10.1093/hmg/ddv126. Epub 2015 Apr 9.

PMID:
25859013
18.

Tumor necrosis factor alpha triggers proliferation of adult neural stem cells via IKK/NF-kappaB signaling.

Widera D, Mikenberg I, Elvers M, Kaltschmidt C, Kaltschmidt B.

BMC Neurosci. 2006 Sep 20;7:64.

19.

Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation.

Nagabhushana A, Bansal M, Swarup G.

PLoS One. 2011 Mar 7;6(3):e17477. doi: 10.1371/journal.pone.0017477.

20.

Effects of optineurin mutants on SH-SY5Y cell survival.

Zhu M, Li A, Chen J, Zhang S, Wu J.

Mol Cell Neurosci. 2016 Jul;74:18-24. doi: 10.1016/j.mcn.2016.03.003. Epub 2016 Mar 5.

PMID:
26956627

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