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Items: 1 to 20 of 58

1.

Cell-type, allelic, and genetic signatures in the human pancreatic beta cell transcriptome.

Nica AC, Ongen H, Irminger JC, Bosco D, Berney T, Antonarakis SE, Halban PA, Dermitzakis ET.

Genome Res. 2013 Sep;23(9):1554-62. doi: 10.1101/gr.150706.112. Epub 2013 May 28.

2.

Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction.

Bugliani M, Liechti R, Cheon H, Suleiman M, Marselli L, Kirkpatrick C, Filipponi F, Boggi U, Xenarios I, Syed F, Ladriere L, Wollheim C, Lee MS, Marchetti P.

Mol Cell Endocrinol. 2013 Mar 10;367(1-2):1-10. doi: 10.1016/j.mce.2012.12.001. Epub 2012 Dec 12.

PMID:
23246353
3.

The pancreatic β-cell transcriptome and integrated-omics.

Blodgett DM, Cura AJ, Harlan DM.

Curr Opin Endocrinol Diabetes Obes. 2014 Apr;21(2):83-8. doi: 10.1097/MED.0000000000000051. Review.

4.

Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes.

Morán I, Akerman I, van de Bunt M, Xie R, Benazra M, Nammo T, Arnes L, Nakić N, García-Hurtado J, Rodríguez-Seguí S, Pasquali L, Sauty-Colace C, Beucher A, Scharfmann R, van Arensbergen J, Johnson PR, Berry A, Lee C, Harkins T, Gmyr V, Pattou F, Kerr-Conte J, Piemonti L, Berney T, Hanley N, Gloyn AL, Sussel L, Langman L, Brayman KL, Sander M, McCarthy MI, Ravassard P, Ferrer J.

Cell Metab. 2012 Oct 3;16(4):435-48. doi: 10.1016/j.cmet.2012.08.010.

5.

Beta cells within single human islets originate from multiple progenitors.

Scharfmann R, Xiao X, Heimberg H, Mallet J, Ravassard P.

PLoS One. 2008;3(10):e3559. doi: 10.1371/journal.pone.0003559. Epub 2008 Oct 29.

6.

Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet β-cells.

Demozay D, Tsunekawa S, Briaud I, Shah R, Rhodes CJ.

Diabetes. 2011 Nov;60(11):2892-902. doi: 10.2337/db11-0341. Epub 2011 Sep 22.

7.

Specific gene expression in pancreatic beta-cells: cloning and characterization of differentially expressed genes.

Arava Y, Adamsky K, Ezerzer C, Ablamunits V, Walker MD.

Diabetes. 1999 Mar;48(3):552-6.

PMID:
10078555
8.

Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.

Li J, Klughammer J, Farlik M, Penz T, Spittler A, Barbieux C, Berishvili E, Bock C, Kubicek S.

EMBO Rep. 2016 Feb;17(2):178-87. doi: 10.15252/embr.201540946. Epub 2015 Dec 21.

9.

Increased neuronal nitric oxide synthase dimerisation is involved in rat and human pancreatic beta cell hyperactivity in obesity.

Mezghenna K, Pomiès P, Chalançon A, Castex F, Leroy J, Niclauss N, Nadal B, Cambier L, Cazevieille C, Petit P, Gomis R, Berney T, Gross R, Lajoix AD.

Diabetologia. 2011 Nov;54(11):2856-66. doi: 10.1007/s00125-011-2264-8. Epub 2011 Aug 18.

PMID:
21847584
10.

A genomic-based approach identifies FXYD domain containing ion transport regulator 2 (FXYD2)gammaa as a pancreatic beta cell-specific biomarker.

Flamez D, Roland I, Berton A, Kutlu B, Dufrane D, Beckers MC, De Waele E, Rooman I, Bouwens L, Clark A, Lonneux M, Jamar JF, Goldman S, Maréchal D, Goodman N, Gianello P, Van Huffel C, Salmon I, Eizirik DL.

Diabetologia. 2010 Jul;53(7):1372-83. doi: 10.1007/s00125-010-1714-z. Epub 2010 Apr 9.

PMID:
20379810
11.

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes.

Igoillo-Esteve M, Marselli L, Cunha DA, Ladrière L, Ortis F, Grieco FA, Dotta F, Weir GC, Marchetti P, Eizirik DL, Cnop M.

Diabetologia. 2010 Jul;53(7):1395-405. doi: 10.1007/s00125-010-1707-y. Epub 2010 Apr 6. Erratum in: Diabetologia. 2012 Mar;55(3):863.

PMID:
20369226
12.

Production and function of IL-12 in islets and beta cells.

Taylor-Fishwick DA, Weaver JR, Grzesik W, Chakrabarti S, Green-Mitchell S, Imai Y, Kuhn N, Nadler JL.

Diabetologia. 2013 Jan;56(1):126-35. doi: 10.1007/s00125-012-2732-9. Epub 2012 Oct 3.

13.

Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.

Serre-Beinier V, Bosco D, Zulianello L, Charollais A, Caille D, Charpantier E, Gauthier BR, Diaferia GR, Giepmans BN, Lupi R, Marchetti P, Deng S, Buhler L, Berney T, Cirulli V, Meda P.

Hum Mol Genet. 2009 Feb 1;18(3):428-39. doi: 10.1093/hmg/ddn370. Epub 2008 Nov 10.

14.

Research resource: RNA-Seq reveals unique features of the pancreatic β-cell transcriptome.

Ku GM, Kim H, Vaughn IW, Hangauer MJ, Myung Oh C, German MS, McManus MT.

Mol Endocrinol. 2012 Oct;26(10):1783-92. Epub 2012 Aug 21.

15.

Isolating human islets of Langerhans causes loss of decay accelerating factor (CD55) on beta-cells.

Tai JH, Sun H, Liu W, Melling CW, Hasilo C, White DJ.

Cell Transplant. 2008;17(12):1349-59.

PMID:
19364072
16.

Effects of biotin supplementation in the diet on insulin secretion, islet gene expression, glucose homeostasis and beta-cell proportion.

Lazo de la Vega-Monroy ML, Larrieta E, German MS, Baez-Saldana A, Fernandez-Mejia C.

J Nutr Biochem. 2013 Jan;24(1):169-77. doi: 10.1016/j.jnutbio.2012.03.020. Epub 2012 Jul 25.

PMID:
22841397
17.

Stimulation of human and rat islet beta-cell proliferation with retention of function by the homeodomain transcription factor Nkx6.1.

Schisler JC, Fueger PT, Babu DA, Hohmeier HE, Tessem JS, Lu D, Becker TC, Naziruddin B, Levy M, Mirmira RG, Newgard CB.

Mol Cell Biol. 2008 May;28(10):3465-76. doi: 10.1128/MCB.01791-07. Epub 2008 Mar 17.

18.

The role of interferon regulatory factor-1 in cytokine-induced mRNA expression and cell death in murine pancreatic beta-cells.

Pavlovic D, Chen MC, Gysemans CA, Mathieu C, Eizirik DL.

Eur Cytokine Netw. 1999 Sep;10(3):403-12.

19.

Analysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and culture.

Negi S, Jetha A, Aikin R, Hasilo C, Sladek R, Paraskevas S.

PLoS One. 2012;7(1):e30415. doi: 10.1371/journal.pone.0030415. Epub 2012 Jan 27.

20.

Obestatin promotes survival of pancreatic beta-cells and human islets and induces expression of genes involved in the regulation of beta-cell mass and function.

Granata R, Settanni F, Gallo D, Trovato L, Biancone L, Cantaluppi V, Nano R, Annunziata M, Campiglia P, Arnoletti E, Ghè C, Volante M, Papotti M, Muccioli G, Ghigo E.

Diabetes. 2008 Apr;57(4):967-79. Epub 2007 Dec 27.

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