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Items: 1 to 20 of 96

1.

p53 promotes inflammation-associated hepatocarcinogenesis by inducing HMGB1 release.

Yan HX, Wu HP, Zhang HL, Ashton C, Tong C, Wu H, Qian QJ, Wang HY, Ying QL.

J Hepatol. 2013 Oct;59(4):762-8. doi: 10.1016/j.jhep.2013.05.029. Epub 2013 May 25.

2.

DNA damage-induced sustained p53 activation contributes to inflammation-associated hepatocarcinogenesis in rats.

Yan HX, Wu HP, Zhang HL, Ashton C, Tong C, Wu J, Qian QJ, Wang HY, Ying QL.

Oncogene. 2013 Sep 19;32(38):4565-71. doi: 10.1038/onc.2012.451. Epub 2012 Oct 15.

3.

Profound impact of gut homeostasis on chemically-induced pro-tumorigenic inflammation and hepatocarcinogenesis in rats.

Zhang HL, Yu LX, Yang W, Tang L, Lin Y, Wu H, Zhai B, Tan YX, Shan L, Liu Q, Chen HY, Dai RY, Qiu BJ, He YQ, Wang C, Zheng LY, Li YQ, Wu FQ, Li Z, Yan HX, Wang HY.

J Hepatol. 2012 Oct;57(4):803-12. doi: 10.1016/j.jhep.2012.06.011. Epub 2012 Jun 19.

PMID:
22727732
4.

Chronic inflammatory IFN-γ signaling suppresses hepatocarcinogenesis in mice by sensitizing hepatocytes for apoptosis.

Lüth S, Schrader J, Zander S, Carambia A, Buchkremer J, Huber S, Reifenberg K, Yamamura K, Schirmacher P, Lohse AW, Herkel J.

Cancer Res. 2011 Jun 1;71(11):3763-71. doi: 10.1158/0008-5472.CAN-10-3232. Epub 2011 Apr 21.

5.

Deletion of IFNγ enhances hepatocarcinogenesis in FXR knockout mice.

Meng Z, Wang X, Gan Y, Zhang Y, Zhou H, Ness CV, Wu J, Lou G, Yu H, He C, Xu R, Huang W.

J Hepatol. 2012 Nov;57(5):1004-12. doi: 10.1016/j.jhep.2012.06.016. Epub 2012 Jun 21.

6.

Growth arrest and DNA damage-inducible protein (GADD34) enhanced liver inflammation and tumorigenesis in a diethylnitrosamine (DEN)-treated murine model.

Chen N, Nishio N, Ito S, Tanaka Y, Sun Y, Isobe K.

Cancer Immunol Immunother. 2015 Jun;64(6):777-89. doi: 10.1007/s00262-015-1690-8. Epub 2015 Apr 2.

PMID:
25832002
7.

Cyclin E facilitates dysplastic hepatocytes to bypass G1/S checkpoint in hepatocarcinogenesis.

Pok S, Wen V, Shackel N, Alsop A, Pyakurel P, Fahrer A, Farrell GC, Teoh NC.

J Gastroenterol Hepatol. 2013 Sep;28(9):1545-54. doi: 10.1111/jgh.12216.

PMID:
23574010
8.

Inhibitory effect of α-lipoic acid on thioacetamide-induced tumor promotion through suppression of inflammatory cell responses in a two-stage hepatocarcinogenesis model in rats.

Fujii Y, Segawa R, Kimura M, Wang L, Ishii Y, Yamamoto R, Morita R, Mitsumori K, Shibutani M.

Chem Biol Interact. 2013 Sep 25;205(2):108-18. doi: 10.1016/j.cbi.2013.06.017. Epub 2013 Jul 2.

PMID:
23830814
9.

Hypoxia induced HMGB1 and mitochondrial DNA interactions mediate tumor growth in hepatocellular carcinoma through Toll-like receptor 9.

Liu Y, Yan W, Tohme S, Chen M, Fu Y, Tian D, Lotze M, Tang D, Tsung A.

J Hepatol. 2015 Jul;63(1):114-21. doi: 10.1016/j.jhep.2015.02.009. Epub 2015 Feb 12.

10.

[Significance of P53 and high mobility group box 1 protein in different levels of liver fibrosis in chronic hepatitis B].

Li L, Chen N, He L, Wen X.

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2015 Nov;40(11):1217-22. doi: 10.11817/j.issn.1672-7347.2015.11.009. Chinese.

11.

p53/HMGB1 complexes regulate autophagy and apoptosis.

Livesey KM, Kang R, Vernon P, Buchser W, Loughran P, Watkins SC, Zhang L, Manfredi JJ, Zeh HJ 3rd, Li L, Lotze MT, Tang D.

Cancer Res. 2012 Apr 15;72(8):1996-2005. doi: 10.1158/0008-5472.CAN-11-2291. Epub 2012 Feb 16.

12.

Myrtenal ameliorates diethylnitrosamine-induced hepatocarcinogenesis through the activation of tumor suppressor protein p53 and regulation of lysosomal and mitochondrial enzymes.

Lingaiah HB, Natarajan N, Thamaraiselvan R, Srinivasan P, Periyasamy BM.

Fundam Clin Pharmacol. 2013 Aug;27(4):443-54. doi: 10.1111/j.1472-8206.2012.01039.x. Epub 2012 Mar 21.

PMID:
22436021
13.

p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes.

Davalos AR, Kawahara M, Malhotra GK, Schaum N, Huang J, Ved U, Beausejour CM, Coppe JP, Rodier F, Campisi J.

J Cell Biol. 2013 May 13;201(4):613-29. doi: 10.1083/jcb.201206006. Epub 2013 May 6.

14.

Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse.

Matsumoto K, Huang J, Viswakarma N, Bai L, Jia Y, Zhu YT, Yang G, Borensztajn J, Rao MS, Zhu YJ, Reddy JK.

Carcinogenesis. 2010 Feb;31(2):318-25. doi: 10.1093/carcin/bgp306. Epub 2009 Dec 9.

15.

β-Catenin loss in hepatocytes promotes hepatocellular cancer after diethylnitrosamine and phenobarbital administration to mice.

Awuah PK, Rhieu BH, Singh S, Misse A, Monga SP.

PLoS One. 2012;7(6):e39771. doi: 10.1371/journal.pone.0039771. Epub 2012 Jun 25.

16.
17.

Targeting high mobility group box protein 1 ameliorates testicular inflammation in experimental autoimmune orchitis.

Aslani F, Schuppe HC, Guazzone VA, Bhushan S, Wahle E, Lochnit G, Lustig L, Meinhardt A, Fijak M.

Hum Reprod. 2015 Feb;30(2):417-31. doi: 10.1093/humrep/deu320. Epub 2014 Dec 1.

PMID:
25452436
18.

The effect of the aqueous extract of the roots of Asparagus racemosus on hepatocarcinogenesis initiated by diethylnitrosamine.

Agrawal A, Sharma M, Rai SK, Singh B, Tiwari M, Chandra R.

Phytother Res. 2008 Sep;22(9):1175-82. doi: 10.1002/ptr.2391.

PMID:
18729252
19.

High Mobility Group Box1 (HMGB1) released from cancer cells induces the expression of pro-inflammatory cytokines in peritoneal fibroblasts.

Abe A, Kuwata T, Yamauchi C, Higuchi Y, Ochiai A.

Pathol Int. 2014 Jun;64(6):267-75. doi: 10.1111/pin.12167.

PMID:
24965109
20.

Sirt1 and HMGB1 Regulate the AGE-Induced Pro-Inflammatory Cytokines in Human Retinal Cells.

Zhang YF, Wei W, Li L, Tu G, Zhang Y, Yang J, Xing Y.

Clin Lab. 2015;61(8):999-1008.

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