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Spinal actions of ω-conotoxins, CVID, MVIIA and related peptides in a rat neuropathic pain model.

Jayamanne A, Jeong HJ, Schroeder CI, Lewis RJ, Christie MJ, Vaughan CW.

Br J Pharmacol. 2013 Sep;170(2):245-54. doi: 10.1111/bph.12251.


Actions of intrathecal omega-conotoxins CVID, GVIA, MVIIA, and morphine in acute and neuropathic pain in the rat.

Scott DA, Wright CE, Angus JA.

Eur J Pharmacol. 2002 Sep 20;451(3):279-86.


omega-Conotoxin inhibition of excitatory synaptic transmission evoked by dorsal root stimulation in rat superficial dorsal horn.

Motin L, Adams DJ.

Neuropharmacology. 2008 Oct;55(5):860-4. doi: 10.1016/j.neuropharm.2008.06.049. Epub 2008 Jul 3.


Antinociceptive effects of the marine snail peptides conantokin-G and conotoxin MVIIA alone and in combination in rat models of pain.

Hama A, Sagen J.

Neuropharmacology. 2009 Feb;56(2):556-63. doi: 10.1016/j.neuropharm.2008.10.008. Epub 2008 Oct 26.


The alpha2delta auxiliary subunit reduces affinity of omega-conotoxins for recombinant N-type (Cav2.2) calcium channels.

Mould J, Yasuda T, Schroeder CI, Beedle AM, Doering CJ, Zamponi GW, Adams DJ, Lewis RJ.

J Biol Chem. 2004 Aug 13;279(33):34705-14. Epub 2004 May 27.


Analgesic (omega)-conotoxins CVIE and CVIF selectively and voltage-dependently block recombinant and native N-type calcium channels.

Berecki G, Motin L, Haythornthwaite A, Vink S, Bansal P, Drinkwater R, Wang CI, Moretta M, Lewis RJ, Alewood PF, Christie MJ, Adams DJ.

Mol Pharmacol. 2010 Feb;77(2):139-48. doi: 10.1124/mol.109.058834. Epub 2009 Nov 5.


Analgesic effect of highly reversible ω-conotoxin FVIA on N type Ca2+ channels.

Lee S, Kim Y, Back SK, Choi HW, Lee JY, Jung HH, Ryu JH, Suh HW, Na HS, Kim HJ, Rhim H, Kim JI.

Mol Pain. 2010 Dec 21;6:97. doi: 10.1186/1744-8069-6-97.


Cardiovascular and autonomic effects of omega-conotoxins MVIIA and CVID in conscious rabbits and isolated tissue assays.

Wright CE, Robertson AD, Whorlow SL, Angus JA.

Br J Pharmacol. 2000 Dec;131(7):1325-36.


Analgesic conotoxins: block and G protein-coupled receptor modulation of N-type (Ca(V) 2.2) calcium channels.

Adams DJ, Callaghan B, Berecki G.

Br J Pharmacol. 2012 May;166(2):486-500. doi: 10.1111/j.1476-5381.2011.01781.x. Review.


Novel omega-conotoxins from Conus catus discriminate among neuronal calcium channel subtypes.

Lewis RJ, Nielsen KJ, Craik DJ, Loughnan ML, Adams DA, Sharpe IA, Luchian T, Adams DJ, Bond T, Thomas L, Jones A, Matheson JL, Drinkwater R, Andrews PR, Alewood PF.

J Biol Chem. 2000 Nov 10;275(45):35335-44.


Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels.

Berecki G, Daly NL, Huang YH, Vink S, Craik DJ, Alewood PF, Adams DJ.

Br J Pharmacol. 2014 Jul;171(13):3313-27. doi: 10.1111/bph.12686.


Blood pressure changes after intrathecal co-administration of calcium channel blockers with morphine or clonidine at the spinal level.

Horvath G, Brodacz B, Holzer-Petsche U.

Naunyn Schmiedebergs Arch Pharmacol. 2002 Sep;366(3):270-5. Epub 2002 Jun 20.


An evaluation of the antinociceptive effects of Phα1β, a neurotoxin from the spider Phoneutria nigriventer, and ω-conotoxin MVIIA, a cone snail Conus magus toxin, in rat model of inflammatory and neuropathic pain.

de Souza AH, Castro CJ Jr, Rigo FK, de Oliveira SM, Gomez RS, Diniz DM, Borges MH, Cordeiro MN, Silva MA, Ferreira J, Gomez MV.

Cell Mol Neurobiol. 2013 Jan;33(1):59-67. doi: 10.1007/s10571-012-9871-x. Epub 2012 Aug 7.


Antiallodynic effect and side effects of Phα1β, a neurotoxin from the spider Phoneutria nigriventer: comparison with ω-conotoxin MVIIA and morphine.

de Souza AH, Lima MC, Drewes CC, da Silva JF, Torres KC, Pereira EM, de Castro Junior CJ, Vieira LB, Cordeiro MN, Richardson M, Gomez RS, Romano-Silva MA, Ferreira J, Gomez MV.

Toxicon. 2011 Dec 1;58(8):626-33. doi: 10.1016/j.toxicon.2011.09.008. Epub 2011 Sep 24.


Effect of ω-conotoxin MVIIA and Phα1β on paclitaxel-induced acute and chronic pain.

Rigo FK, Dalmolin GD, Trevisan G, Tonello R, Silva MA, Rossato MF, Klafke JZ, Cordeiro Mdo N, Castro Junior CJ, Montijo D, Gomez MV, Ferreira J.

Pharmacol Biochem Behav. 2013 Dec;114-115:16-22. doi: 10.1016/j.pbb.2013.10.014. Epub 2013 Oct 19.


Omega-conotoxin CVIB differentially inhibits native and recombinant N- and P/Q-type calcium channels.

Motin L, Yasuda T, Schroeder CI, Lewis RJ, Adams DJ.

Eur J Neurosci. 2007 Jan;25(2):435-44.


omega-Conotoxins block neurotransmission in the rat vas deferens by binding to different presynaptic sites on the N-type Ca2+ channel.

Hirata H, Albillos A, Fernández F, Medrano J, Jurkiewicz A, García AG.

Eur J Pharmacol. 1997 Feb 26;321(2):217-23.


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