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Scavenger receptor B1 post-translational modifications in Rett syndrome.

Sticozzi C, Belmonte G, Pecorelli A, Cervellati F, Leoncini S, Signorini C, Ciccoli L, De Felice C, Hayek J, Valacchi G.

FEBS Lett. 2013 Jul 11;587(14):2199-204. doi: 10.1016/j.febslet.2013.05.042. Epub 2013 May 24.


Scavenger Receptor B1 oxidative post-translational modifications are responsible for its loss in Rett syndrome.

Valacchi G, Sticozzi C, Belmonte G, Cervellati F, Pecorelli A, Signorini C, Leoncini S, Ciccoli L, De Felice C, Della Ragione F, Scalabri F, Marracino F, Madonna M, D'Esposito M, Joussef H, Cervellati F, Stefania F.

Free Radic Biol Med. 2014 Oct;75 Suppl 1:S10-1. doi: 10.1016/j.freeradbiomed.2014.10.855. Epub 2014 Dec 10.


Alteration of serum lipid profile, SRB1 loss, and impaired Nrf2 activation in CDKL5 disorder.

Pecorelli A, Belmonte G, Meloni I, Cervellati F, Gardi C, Sticozzi C, De Felice C, Signorini C, Cortelazzo A, Leoncini S, Ciccoli L, Renieri A, Jay Forman H, Hayek J, Valacchi G.

Free Radic Biol Med. 2015 Sep;86:156-65. doi: 10.1016/j.freeradbiomed.2015.05.010. Epub 2015 May 22.


Cholesterol metabolism is altered in Rett syndrome: a study on plasma and primary cultured fibroblasts derived from patients.

Segatto M, Trapani L, Di Tunno I, Sticozzi C, Valacchi G, Hayek J, Pallottini V.

PLoS One. 2014 Aug 12;9(8):e104834. doi: 10.1371/journal.pone.0104834. eCollection 2014 Aug 12. Erratum in: PLoS One. 2014;9(11):e114654.


Beta-actin deficiency with oxidative posttranslational modifications in Rett syndrome erythrocytes: insights into an altered cytoskeletal organization.

Cortelazzo A, De Felice C, Pecorelli A, Belmonte G, Signorini C, Leoncini S, Zollo G, Capone A, Giovampaola CD, Sticozzi C, Valacchi G, Ciccoli L, Guerranti R, Hayek J.

PLoS One. 2014 Mar 26;9(3):e93181. doi: 10.1371/journal.pone.0093181. eCollection 2014 Mar 26.


Increased levels of 4HNE-protein plasma adducts in Rett syndrome.

Pecorelli A, Ciccoli L, Signorini C, Leoncini S, Giardini A, D'Esposito M, Filosa S, Hayek J, De Felice C, Valacchi G.

Clin Biochem. 2011 Apr;44(5-6):368-71. doi: 10.1016/j.clinbiochem.2011.01.007. Epub 2011 Jan 26.


F2-dihomo-isoprostanes as potential early biomarkers of lipid oxidative damage in Rett syndrome.

De Felice C, Signorini C, Durand T, Oger C, Guy A, Bultel-Poncé V, Galano JM, Ciccoli L, Leoncini S, D'Esposito M, Filosa S, Pecorelli A, Valacchi G, Hayek J.

J Lipid Res. 2011 Dec;52(12):2287-97. doi: 10.1194/jlr.P017798. Epub 2011 Sep 13.


Isoprostanes and 4-hydroxy-2-nonenal: markers or mediators of disease? Focus on Rett syndrome as a model of autism spectrum disorder.

Signorini C, De Felice C, Durand T, Oger C, Galano JM, Leoncini S, Pecorelli A, Valacchi G, Ciccoli L, Hayek J.

Oxid Med Cell Longev. 2013;2013:343824. doi: 10.1155/2013/343824. Epub 2013 Jun 13. Review.


Cigarette smoke affects keratinocytes SRB1 expression and localization via H2O2 production and HNE protein adducts formation.

Sticozzi C, Belmonte G, Pecorelli A, Arezzini B, Gardi C, Maioli E, Miracco C, Toscano M, Forman HJ, Valacchi G.

PLoS One. 2012;7(3):e33592. doi: 10.1371/journal.pone.0033592. Epub 2012 Mar 19.


Exploring the possible link between MeCP2 and oxidative stress in Rett syndrome.

Filosa S, Pecorelli A, D'Esposito M, Valacchi G, Hajek J.

Free Radic Biol Med. 2015 Nov;88(Pt A):81-90. doi: 10.1016/j.freeradbiomed.2015.04.019. Epub 2015 May 8. Review.


Altered erythrocyte membrane fatty acid profile in typical Rett syndrome: effects of omega-3 polyunsaturated fatty acid supplementation.

Signorini C, De Felice C, Leoncini S, Durand T, Galano JM, Cortelazzo A, Zollo G, Guerranti R, Gonnelli S, Caffarelli C, Rossi M, Pecorelli A, Valacchi G, Ciccoli L, Hayek J.

Prostaglandins Leukot Essent Fatty Acids. 2014 Nov;91(5):183-93. doi: 10.1016/j.plefa.2014.08.002. Epub 2014 Sep 6.


Cigarette smoke exposure causes changes in Scavenger Receptor B1 level and distribution in lung cells.

Valacchi G, Davis PA, Khan EM, Lanir R, Maioli E, Pecorelli A, Cross CE, Goldkorn T.

Int J Biochem Cell Biol. 2011 Jul;43(7):1065-70. doi: 10.1016/j.biocel.2009.05.014. Epub 2009 Jun 2.


The Srb1+1050T allele is associated with metabolic syndrome in children but not with cholesteryl ester plasma concentrations of high-density lipoprotein subclasses.

Juárez-Meavepeña M, Carreón-Torres E, López-Osorio C, García-Sánchez C, Gamboa R, Torres-Tamayo M, Fragoso JM, Rodríguez-Pérez JM, Vargas-Alarcón G, Pérez-Méndez O.

Metab Syndr Relat Disord. 2012 Apr;10(2):110-6. doi: 10.1089/met.2011.0071. Epub 2011 Dec 19.


Redox imbalance and morphological changes in skin fibroblasts in typical Rett syndrome.

Signorini C, Leoncini S, De Felice C, Pecorelli A, Meloni I, Ariani F, Mari F, Amabile S, Paccagnini E, Gentile M, Belmonte G, Zollo G, Valacchi G, Durand T, Galano JM, Ciccoli L, Renieri A, Hayek J.

Oxid Med Cell Longev. 2014;2014:195935. doi: 10.1155/2014/195935. Epub 2014 May 29.


SRB1 as a new redox target of cigarette smoke in human sebocytes.

Crivellari I, Sticozzi C, Belmonte G, Muresan XM, Cervellati F, Pecorelli A, Cavicchio C, Maioli E, Zouboulis CC, Benedusi M, Cervellati C, Valacchi G.

Free Radic Biol Med. 2017 Jan;102:47-56. doi: 10.1016/j.freeradbiomed.2016.11.021. Epub 2016 Nov 16.


Plasma fatty acid changes and increased lipid peroxidation in patients with adult respiratory distress syndrome.

Quinlan GJ, Lamb NJ, Evans TW, Gutteridge JM.

Crit Care Med. 1996 Feb;24(2):241-6.


Cytokines profile and peripheral blood mononuclear cells morphology in Rett and autistic patients.

Pecorelli A, Cervellati F, Belmonte G, Montagner G, Waldon P, Hayek J, Gambari R, Valacchi G.

Cytokine. 2016 Jan;77:180-8. doi: 10.1016/j.cyto.2015.10.002. Epub 2015 Oct 21.


Novel alterations in the epigenetic signature of MeCP2-targeted promoters in lymphocytes of Rett syndrome patients.

Lilja T, Wallenborg K, Björkman K, Albåge M, Eriksson M, Lagercrantz H, Rohdin M, Hermanson O.

Epigenetics. 2013 Mar;8(3):246-51. doi: 10.4161/epi.23752. Epub 2013 Jan 24.


Mitochondrial free radical overproduction due to respiratory chain impairment in the brain of a mouse model of Rett syndrome: protective effect of CNF1.

De Filippis B, Valenti D, de Bari L, De Rasmo D, Musto M, Fabbri A, Ricceri L, Fiorentini C, Laviola G, Vacca RA.

Free Radic Biol Med. 2015 Jun;83:167-77. doi: 10.1016/j.freeradbiomed.2015.02.014. Epub 2015 Feb 20.


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