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Items: 1 to 20 of 200

1.

Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells.

Wu T, Young JS, Johnston H, Ni X, Deng R, Racine J, Wang M, Wang A, Todorov I, Wang J, Zeng D.

J Immunol. 2013 Jul 1;191(1):488-99. doi: 10.4049/jimmunol.1300657. Epub 2013 May 24.

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Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease.

Zhao D, Young JS, Chen YH, Shen E, Yi T, Todorov I, Chu PG, Forman SJ, Zeng D.

J Immunol. 2011 Jan 15;186(2):856-68. doi: 10.4049/jimmunol.1002195. Epub 2010 Dec 13.

4.

Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4+ T cells that mediate autoimmune-like chronic graft-versus-host disease.

Young JS, Wu T, Chen Y, Zhao D, Liu H, Yi T, Johnston H, Racine J, Li X, Wang A, Todorov I, Zeng D.

J Immunol. 2012 Jul 1;189(1):222-33. doi: 10.4049/jimmunol.1200677. Epub 2012 May 30.

5.

MHC-mismatched mixed chimerism augments thymic regulatory T-cell production and prevents relapse of EAE in mice.

Wu L, Li N, Zhang M, Xue SL, Cassady K, Lin Q, Riggs AD, Zeng D.

Proc Natl Acad Sci U S A. 2015 Dec 29;112(52):15994-9. doi: 10.1073/pnas.1521157112. Epub 2015 Dec 8.

6.

Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease.

Sakoda Y, Hashimoto D, Asakura S, Takeuchi K, Harada M, Tanimoto M, Teshima T.

Blood. 2007 Feb 15;109(4):1756-64. Epub 2006 Oct 10.

7.

Inhibition of graft-versus-host disease by double-negative regulatory T cells.

Young KJ, DuTemple B, Phillips MJ, Zhang L.

J Immunol. 2003 Jul 1;171(1):134-41.

8.

Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations.

Zhang C, Todorov I, Zhang Z, Liu Y, Kandeel F, Forman S, Strober S, Zeng D.

Blood. 2006 Apr 1;107(7):2993-3001. Epub 2005 Dec 13.

9.

Induction of lethal graft-versus-host disease by anti-CD137 monoclonal antibody in mice prone to chronic graft-versus-host disease.

Kim W, Kim J, Jung D, Kim H, Choi HJ, Cho HR, Kwon B.

Biol Blood Marrow Transplant. 2009 Mar;15(3):306-14. doi: 10.1016/j.bbmt.2008.11.035.

10.

Administration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effects.

Johnston HF, Xu Y, Racine JJ, Cassady K, Ni X, Wu T, Chan A, Forman S, Zeng D.

Biol Blood Marrow Transplant. 2014 Aug;20(8):1089-103. doi: 10.1016/j.bbmt.2014.04.028. Epub 2014 May 4.

11.

Impaired thymic negative selection causes autoimmune graft-versus-host disease.

Teshima T, Reddy P, Liu C, Williams D, Cooke KR, Ferrara JL.

Blood. 2003 Jul 15;102(2):429-35. Epub 2003 Mar 27.

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T cells, murine chronic graft-versus-host disease and autoimmunity.

Eisenberg RA, Via CS.

J Autoimmun. 2012 Sep;39(3):240-7. doi: 10.1016/j.jaut.2012.05.017. Epub 2012 Jun 16. Review.

15.

Breaking of CD8+ T cell tolerance through in vivo ligation of CD40 results in inhibition of chronic graft-versus-host disease and complete donor cell engraftment.

Kim J, Park K, Kim HJ, Kim J, Kim HA, Jung D, Kim HJ, Choi HJ, Choi SY, Seo KW, Cho HR, Kwon B.

J Immunol. 2008 Nov 15;181(10):7380-9.

16.

Graft-vs.-host and graft-vs.-leukemia reactions after delayed infusions of donor T-subsets.

Johnson BD, Becker EE, Truitt RL.

Biol Blood Marrow Transplant. 1999;5(3):123-32.

17.

Unique abnormalities of CD4(+) and CD8(+) central memory cells associated with chronic graft-versus-host disease improve after extracorporeal photopheresis.

Yamashita K, Horwitz ME, Kwatemaa A, Nomicos E, Castro K, Sokolic R, Foster SF, Garofalo M, Choi U, Ryherd M, Brown MR, Leitman SF, Wayne AS, Fowler DH, Bishop MR, Childs RW, Barrett AJ, Pavletic SZ, Malech HL.

Biol Blood Marrow Transplant. 2006 Jan;12(1 Suppl 2):22-30.

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