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Items: 1 to 20 of 159


Local constraints in either the GluN1 or GluN2 subunit equally impair NMDA receptor pore opening.

Talukder I, Wollmuth LP.

J Gen Physiol. 2011 Aug;138(2):179-94. doi: 10.1085/jgp.201110623. Epub 2011 Jul 11.


Subunit-specific contribution of pore-forming domains to NMDA receptor channel structure and gating.

Sobolevsky AI, Prodromou ML, Yelshansky MV, Wollmuth LP.

J Gen Physiol. 2007 Jun;129(6):509-25. Epub 2007 May 15.


Asynchronous movements prior to pore opening in NMDA receptors.

Kazi R, Gan Q, Talukder I, Markowitz M, Salussolia CL, Wollmuth LP.

J Neurosci. 2013 Jul 17;33(29):12052-66. doi: 10.1523/JNEUROSCI.5780-12.2013.


Probing the activation sequence of NMDA receptors with lurcher mutations.

Murthy SE, Shogan T, Page JC, Kasperek EM, Popescu GK.

J Gen Physiol. 2012 Sep;140(3):267-77. doi: 10.1085/jgp.201210786. Epub 2012 Aug 13.


Arrangement of subunits in functional NMDA receptors.

Salussolia CL, Prodromou ML, Borker P, Wollmuth LP.

J Neurosci. 2011 Aug 3;31(31):11295-304. doi: 10.1523/JNEUROSCI.5612-10.2011.


Structure-based discovery of antagonists for GluN3-containing N-methyl-D-aspartate receptors.

Kvist T, Greenwood JR, Hansen KB, Traynelis SF, Bräuner-Osborne H.

Neuropharmacology. 2013 Dec;75:324-36. doi: 10.1016/j.neuropharm.2013.08.003. Epub 2013 Aug 22.


Separate intramolecular targets for protein kinase A control N-methyl-D-aspartate receptor gating and Ca2+ permeability.

Aman TK, Maki BA, Ruffino TJ, Kasperek EM, Popescu GK.

J Biol Chem. 2014 Jul 4;289(27):18805-17. doi: 10.1074/jbc.M113.537282. Epub 2014 May 20.


GluN1-specific redox effects on the kinetic mechanism of NMDA receptor activation.

Talukder I, Kazi R, Wollmuth LP.

Biophys J. 2011 Nov 16;101(10):2389-98. doi: 10.1016/j.bpj.2011.10.015. Epub 2011 Nov 15.


Disruption of S2-M4 linker coupling reveals novel subunit-specific contributions to N-methyl-d-aspartate receptor function and ethanol sensitivity.

Hughes BA, Woodward JJ.

Neuropharmacology. 2016 Jun;105:96-105. doi: 10.1016/j.neuropharm.2015.11.009. Epub 2015 Nov 11.


Conserved structural and functional control of N-methyl-D-aspartate receptor gating by transmembrane domain M3.

Yuan H, Erreger K, Dravid SM, Traynelis SF.

J Biol Chem. 2005 Aug 19;280(33):29708-16. Epub 2005 Jun 21.


Specific sites within the ligand-binding domain and ion channel linkers modulate NMDA receptor gating.

Talukder I, Borker P, Wollmuth LP.

J Neurosci. 2010 Sep 1;30(35):11792-804. doi: 10.1523/JNEUROSCI.5382-09.2010.


Kinetic contributions to gating by interactions unique to N-methyl-D-aspartate (NMDA) receptors.

Borschel WF, Cummings KA, Tindell LK, Popescu GK.

J Biol Chem. 2015 Oct 30;290(44):26846-55. doi: 10.1074/jbc.M115.678656. Epub 2015 Sep 14.


Ethanol inhibition of constitutively open N-methyl-D-aspartate receptors.

Xu M, Smothers CT, Trudell J, Woodward JJ.

J Pharmacol Exp Ther. 2012 Jan;340(1):218-26. doi: 10.1124/jpet.111.187179. Epub 2011 Oct 17.


Identification of a single amino acid in GluN1 that is critical for glycine-primed internalization of NMDA receptors.

Han L, Campanucci VA, Cooke J, Salter MW.

Mol Brain. 2013 Aug 13;6:36. doi: 10.1186/1756-6606-6-36.


Modal gating of GluN1/GluN2D NMDA receptors.

Vance KM, Hansen KB, Traynelis SF.

Neuropharmacology. 2013 Aug;71:184-90. doi: 10.1016/j.neuropharm.2013.03.018. Epub 2013 Apr 8.


All atom NMDA receptor transmembrane domain model development and simulations in lipid bilayers and water.

Mesbahi-Vasey S, Veras L, Yonkunas M, Johnson JW, Kurnikova MG.

PLoS One. 2017 Jun 5;12(6):e0177686. doi: 10.1371/journal.pone.0177686. eCollection 2017.


Interactions among positions in the third and fourth membrane-associated domains at the intersubunit interface of the N-methyl-D-aspartate receptor forming sites of alcohol action.

Ren H, Zhao Y, Dwyer DS, Peoples RW.

J Biol Chem. 2012 Aug 10;287(33):27302-12. doi: 10.1074/jbc.M111.338921. Epub 2012 Jun 19.


Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors.

Hansen KB, Tajima N, Risgaard R, Perszyk RE, Jørgensen L, Vance KM, Ogden KK, Clausen RP, Furukawa H, Traynelis SF.

Mol Pharmacol. 2013 Jul;84(1):114-27. doi: 10.1124/mol.113.085803. Epub 2013 Apr 26.


Amino terminal domains of the NMDA receptor are organized as local heterodimers.

Lee CH, Gouaux E.

PLoS One. 2011 Apr 22;6(4):e19180. doi: 10.1371/journal.pone.0019180.

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