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Items: 1 to 20 of 98

1.

The association of adipose-derived dimethylarginine dimethylaminohydrolase-2 with insulin sensitivity in experimental type 2 diabetes mellitus.

Zheng J, Wang K, Jin P, Dong C, Yuan Q, Li Y, Yang Z.

Acta Biochim Biophys Sin (Shanghai). 2013 Aug;45(8):641-8. doi: 10.1093/abbs/gmt058. Epub 2013 May 23.

PMID:
23702602
2.

The role of adipose tissue asymmetric dimethylarginine/dimethylarginine dimethylaminohydrolase pathway in adipose tissue phenotype and metabolic abnormalities in subtotally nephrectomized rats.

Minakuchi H, Wakino S, Hosoya K, Sueyasu K, Hasegawa K, Shinozuka K, Yoshifuji A, Futatsugi K, Komatsu M, Kanda T, Tokuyama H, Hayashi K, Itoh H.

Nephrol Dial Transplant. 2016 Mar;31(3):413-23. doi: 10.1093/ndt/gfv367. Epub 2015 Oct 28.

PMID:
26516203
3.

Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase.

Lin KY, Ito A, Asagami T, Tsao PS, Adimoolam S, Kimoto M, Tsuji H, Reaven GM, Cooke JP.

Circulation. 2002 Aug 20;106(8):987-92.

4.

Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis.

Park K, Lee DG, Kim SW, Paick JS.

Int J Impot Res. 2009 Jul-Aug;21(4):228-34. doi: 10.1038/ijir.2009.20. Epub 2009 Jun 18.

5.

Pyrrolidine dithiocarbamate ameliorates endothelial dysfunction in thoracic aorta of diabetic rats by preserving vascular DDAH activity.

Lu CW, Lin Y, Lei YP, Wang L, He ZM, Xiong Y.

PLoS One. 2017 Jul 17;12(7):e0179908. doi: 10.1371/journal.pone.0179908. eCollection 2017.

6.

GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in humans.

Chobanyan K, Thum T, Suchy MT, Zhu B, Mitschke A, Gutzki FM, Beckmann B, Stichtenoth DO, Tsikas D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 15;858(1-2):32-41. Epub 2007 Aug 7.

PMID:
17825631
7.

Ex vivo gene transferring of human dimethylarginine dimethylaminohydrolase-2 improved endothelial dysfunction in diabetic rat aortas and high glucose-treated endothelial cells.

Lu CW, Guo Z, Feng M, Wu ZZ, He ZM, Xiong Y.

Atherosclerosis. 2010 Mar;209(1):66-73. doi: 10.1016/j.atherosclerosis.2009.08.035. Epub 2009 Aug 28.

PMID:
19775692
8.

Asymmetric dimethylarginine impairs glucose utilization via ROS/TLR4 pathway in adipocytes: an effect prevented by vitamin E.

Yang ZC, Wang KS, Wu Y, Zou XQ, Xiang YY, Chen XP, Li YJ.

Cell Physiol Biochem. 2009;24(1-2):115-24. doi: 10.1159/000227819. Epub 2009 Jul 1.

9.

Involvement of increased endogenous asymmetric dimethylarginine in the hepatic endoplasmic reticulum stress of type 2 diabetic rats.

Leng YP, Qiu N, Fang WJ, Zhang M, He ZM, Xiong Y.

PLoS One. 2014 Jun 11;9(2):e97125. doi: 10.1371/journal.pone.0097125. eCollection 2014.

10.

Inhibitory effect of resveratrol derivative BTM-0512 on high glucose-induced cell senescence involves dimethylaminohydrolase/asymmetric dimethylarginine pathway.

Yuan Q, Peng J, Liu SY, Wang CJ, Xiang DX, Xiong XM, Hu CP, Li YJ.

Clin Exp Pharmacol Physiol. 2010 May;37(5-6):630-5. doi: 10.1111/j.1440-1681.2010.05368.x. Epub 2010 Feb 4.

PMID:
20132235
11.
12.

Dimethylarginine dimethylaminohydrolase overexpression enhances insulin sensitivity.

Sydow K, Mondon CE, Schrader J, Konishi H, Cooke JP.

Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):692-7. doi: 10.1161/ATVBAHA.108.162073. Epub 2008 Jan 31.

13.

Accelerated onset of senescence of endothelial progenitor cells in patients with type 2 diabetes mellitus: role of dimethylarginine dimethylaminohydrolase 2 and asymmetric dimethylarginine.

Yuan Q, Hu CP, Gong ZC, Bai YP, Liu SY, Li YJ, Jiang JL.

Biochem Biophys Res Commun. 2015 Mar 20;458(4):869-76. doi: 10.1016/j.bbrc.2015.02.050. Epub 2015 Feb 18.

PMID:
25701782
14.

Dimethylarginine dimethylaminohydrolase (DDAH) regulates trophoblast invasion and motility through effects on nitric oxide.

Ayling LJ, Whitley GS, Aplin JD, Cartwright JE.

Hum Reprod. 2006 Oct;21(10):2530-7. Epub 2006 Aug 18.

PMID:
16920729
15.

Pioglitazone lowers systemic asymmetric dimethylarginine by inducing dimethylarginine dimethylaminohydrolase in rats.

Wakino S, Hayashi K, Tatematsu S, Hasegawa K, Takamatsu I, Kanda T, Homma K, Yoshioka K, Sugano N, Saruta T.

Hypertens Res. 2005 Mar;28(3):255-62.

PMID:
16097370
16.

Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension.

Millatt LJ, Whitley GS, Li D, Leiper JM, Siragy HM, Carey RM, Johns RA.

Circulation. 2003 Sep 23;108(12):1493-8. Epub 2003 Sep 2.

17.

A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with insulin sensitivity.

Andreozzi F, Presta I, Mannino GC, Scarpelli D, Di Silvestre S, Di Pietro N, Succurro E, Sciacqua A, Pandolfi A, Consoli A, Hribal ML, Perticone F, Sesti G.

PLoS One. 2012;7(4):e36224. doi: 10.1371/journal.pone.0036224. Epub 2012 Apr 27.

18.
19.

Involvement of asymmetric dimethylarginine (ADMA) in tubulointerstitial ischaemia in the early phase of diabetic nephropathy.

Shibata R, Ueda S, Yamagishi S, Kaida Y, Matsumoto Y, Fukami K, Hayashida A, Matsuoka H, Kato S, Kimoto M, Okuda S.

Nephrol Dial Transplant. 2009 Apr;24(4):1162-9. doi: 10.1093/ndt/gfn630. Epub 2008 Nov 17.

PMID:
19015171
20.

[Effects of insulin on pigment epithelium-derived factor expression in adipocytes of type 2 diabetic mellitus in rats].

Xu F, Lin B, Zhou Y, Deng H, Bi Y, Liang H.

Zhonghua Yi Xue Za Zhi. 2014 Oct 21;94(38):2992-5. Chinese.

PMID:
25547701

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