Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 105

1.

Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach.

Duffy MR, Parker AL, Kalkman ER, White K, Kovalskyy D, Kelly SM, Baker AH.

J Control Release. 2013 Aug 28;170(1):132-40. doi: 10.1016/j.jconrel.2013.05.007. Epub 2013 May 20.

2.

Manipulating adenovirus hexon hypervariable loops dictates immune neutralisation and coagulation factor X-dependent cell interaction in vitro and in vivo.

Ma J, Duffy MR, Deng L, Dakin RS, Uil T, Custers J, Kelly SM, McVey JH, Nicklin SA, Baker AH.

PLoS Pathog. 2015 Feb 6;11(2):e1004673. doi: 10.1371/journal.ppat.1004673. eCollection 2015 Feb.

3.

Requirements for receptor engagement during infection by adenovirus complexed with blood coagulation factor X.

Bradshaw AC, Parker AL, Duffy MR, Coughlan L, van Rooijen N, Kähäri VM, Nicklin SA, Baker AH.

PLoS Pathog. 2010 Oct 7;6(10):e1001142. doi: 10.1371/journal.ppat.1001142.

4.

Influence of coagulation factor x on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors.

Greig JA, Buckley SM, Waddington SN, Parker AL, Bhella D, Pink R, Rahim AA, Morita T, Nicklin SA, McVey JH, Baker AH.

Mol Ther. 2009 Oct;17(10):1683-91. doi: 10.1038/mt.2009.152. Epub 2009 Jul 14. Erratum in: Mol Ther. 2009 Oct;17(10):1830.

5.

Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors.

Alba R, Bradshaw AC, Coughlan L, Denby L, McDonald RA, Waddington SN, Buckley SM, Greig JA, Parker AL, Miller AM, Wang H, Lieber A, van Rooijen N, McVey JH, Nicklin SA, Baker AH.

Blood. 2010 Oct 14;116(15):2656-64. doi: 10.1182/blood-2009-12-260026. Epub 2010 Jul 7.

7.

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer.

Alba R, Bradshaw AC, Parker AL, Bhella D, Waddington SN, Nicklin SA, van Rooijen N, Custers J, Goudsmit J, Barouch DH, McVey JH, Baker AH.

Blood. 2009 Jul 30;114(5):965-71. doi: 10.1182/blood-2009-03-208835. Epub 2009 May 8.

8.

Biodistribution and inflammatory profiles of novel penton and hexon double-mutant serotype 5 adenoviruses.

Bradshaw AC, Coughlan L, Miller AM, Alba R, van Rooijen N, Nicklin SA, Baker AH.

J Control Release. 2012 Dec 28;164(3):394-402. doi: 10.1016/j.jconrel.2012.05.025. Epub 2012 May 22.

9.

Influence of fiber detargeting on adenovirus-mediated innate and adaptive immune activation.

Schoggins JW, Nociari M, Philpott N, Falck-Pedersen E.

J Virol. 2005 Sep;79(18):11627-37.

10.

Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy.

Short JJ, Rivera AA, Wu H, Walter MR, Yamamoto M, Mathis JM, Curiel DT.

Mol Cancer Ther. 2010 Sep;9(9):2536-44. doi: 10.1158/1535-7163.MCT-10-0332. Epub 2010 Aug 24.

11.

Fiber-knob modifications enhance adenoviral tropism and gene transfer in malignant glioma.

Zheng S, Ulasov IV, Han Y, Tyler MA, Zhu ZB, Lesniak MS.

J Gene Med. 2007 Mar;9(3):151-60.

PMID:
17351980
12.

Genetic replacement of the adenovirus shaft fiber reduces liver tropism in ovarian cancer gene therapy.

Breidenbach M, Rein DT, Wang M, Nettelbeck DM, Hemminki A, Ulasov I, Rivera AR, Everts M, Alvarez RD, Douglas JT, Curiel DT.

Hum Gene Ther. 2004 May;15(5):509-18.

PMID:
15144580
13.

Mouse adenovirus type 1 and human adenovirus type 5 differ in endothelial cell tropism and liver targeting.

Lenaerts L, McVey JH, Baker AH, Denby L, Nicklin S, Verbeken E, Naesens L.

J Gene Med. 2009 Feb;11(2):119-27. doi: 10.1002/jgm.1283.

PMID:
19065608
14.

Coagulation factor X mediates adenovirus type 5 liver gene transfer in non-human primates (Microcebus murinus).

Alba R, Bradshaw AC, Mestre-Francés N, Verdier JM, Henaff D, Baker AH.

Gene Ther. 2012 Jan;19(1):109-13. doi: 10.1038/gt.2011.87. Epub 2011 Jun 16.

15.

Hepatocyte Heparan Sulfate Is Required for Adeno-Associated Virus 2 but Dispensable for Adenovirus 5 Liver Transduction In Vivo.

Zaiss AK, Foley EM, Lawrence R, Schneider LS, Hoveida H, Secrest P, Catapang AB, Yamaguchi Y, Alemany R, Shayakhmetov DM, Esko JD, Herschman HR.

J Virol. 2015 Oct 21;90(1):412-20. doi: 10.1128/JVI.01939-15.

16.

Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5.

Waddington SN, Parker AL, Havenga M, Nicklin SA, Buckley SM, McVey JH, Baker AH.

J Virol. 2007 Sep;81(17):9568-71. Epub 2007 Jun 6.

17.

Genetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy.

Han T, Tang Y, Ugai H, Perry LE, Siegal GP, Contreras JL, Wu H.

Virol J. 2007 Oct 24;4:103.

18.

Adenovirus vectors composed of subgroup B adenoviruses.

Sakurai F, Kawabata K, Mizuguchi H.

Curr Gene Ther. 2007 Aug;7(4):229-38. Review.

PMID:
17969556
19.

Effect of neutralizing sera on factor x-mediated adenovirus serotype 5 gene transfer.

Parker AL, Waddington SN, Buckley SM, Custers J, Havenga MJ, van Rooijen N, Goudsmit J, McVey JH, Nicklin SA, Baker AH.

J Virol. 2009 Jan;83(1):479-83. doi: 10.1128/JVI.01878-08. Epub 2008 Oct 22.

Supplemental Content

Support Center