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Items: 1 to 20 of 106

1.

A novel assay platform for the detection of translation modulators of spermidine/spermine acetyltransferase.

Perez-Leal O, Abou-Gharbia M, Gordon J, Childers WE, Merali S.

Curr Pharm Des. 2014;20(2):245-52.

2.

Polyamine catabolism in platinum drug action: Interactions between oxaliplatin and the polyamine analogue N1,N11-diethylnorspermine at the level of spermidine/spermine N1-acetyltransferase.

Hector S, Porter CW, Kramer DL, Clark K, Prey J, Kisiel N, Diegelman P, Chen Y, Pendyala L.

Mol Cancer Ther. 2004 Jul;3(7):813-22.

5.

Polyamine and polyamine analog regulation of spermidine/spermine N1-acetyltransferase in MALME-3M human melanoma cells.

Fogel-Petrovic M, Shappell NW, Bergeron RJ, Porter CW.

J Biol Chem. 1993 Sep 5;268(25):19118-25.

6.

Polyamine-dependent regulation of spermidine-spermine N1-acetyltransferase mRNA translation.

Butcher NJ, Broadhurst GM, Minchin RF.

J Biol Chem. 2007 Sep 28;282(39):28530-9. Epub 2007 Aug 9.

7.

Effects of polyamines, polyamine analogs, and inhibitors of protein synthesis on spermidine-spermine N1-acetyltransferase gene expression.

Fogel-Petrovic M, Vujcic S, Brown PJ, Haddox MK, Porter CW.

Biochemistry. 1996 Nov 12;35(45):14436-44.

PMID:
8916930
8.

Spermine analogue-regulated expression of spermidine/spermine N1-acetyltransferase and its effects on depletion of intracellular polyamine pools in mouse fetal fibroblasts.

Uimari A, Keinänen TA, Karppinen A, Woster P, Uimari P, Jänne J, Alhonen L.

Biochem J. 2009 Jul 29;422(1):101-9. doi: 10.1042/BJ20090411.

9.

Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants.

Tummala R, Diegelman P, Hector S, Kramer DL, Clark K, Zagst P, Fetterly G, Porter CW, Pendyala L.

Cancer Chemother Pharmacol. 2011 Feb;67(2):401-14. doi: 10.1007/s00280-010-1334-9. Epub 2010 May 5.

10.

Correlation of polyamine and growth responses to N1,N11-diethylnorspermine in primary fetal fibroblasts derived from transgenic mice overexpressing spermidine/spermine N1-acetyltransferase.

Alhonen L, Karppinen A, Uusi-Oukari M, Vujcic S, Korhonen VP, Halmekytö M, Kramer DL, Hines R, Jänne J, Porter CW.

J Biol Chem. 1998 Jan 23;273(4):1964-9.

11.
12.

Overexpression of spermidine/spermine N1-acetyltransferase or treatment with N1-N11-diethylnorspermine attenuates the severity of zinc-induced pancreatitis in mouse.

Uimari A, Merentie M, Sironen R, Pirnes-Karhu S, Peräniemi S, Alhonen L.

Amino Acids. 2012 Feb;42(2-3):461-71. doi: 10.1007/s00726-011-1025-9. Epub 2011 Aug 4.

PMID:
21814793
13.

Mice with targeted disruption of spermidine/spermine N1-acetyltransferase gene maintain nearly normal tissue polyamine homeostasis but show signs of insulin resistance upon aging.

Niiranen K, Keinänen TA, Pirinen E, Heikkinen S, Tusa M, Fatrai S, Suppola S, Pietilä M, Uimari A, Laakso M, Alhonen L, Jänne J.

J Cell Mol Med. 2006 Oct-Dec;10(4):933-45.

14.
15.

Activation of polyamine catabolism in transgenic rats induces acute pancreatitis.

Alhonen L, Parkkinen JJ, Keinanen T, Sinervirta R, Herzig KH, Jänne J.

Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8290-5.

16.
17.

Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine.

Hector S, Tummala R, Kisiel ND, Diegelman P, Vujcic S, Clark K, Fakih M, Kramer DL, Porter CW, Pendyala L.

Cancer Chemother Pharmacol. 2008 Aug;62(3):517-27. Epub 2007 Nov 7.

PMID:
17987291
18.

Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N(1)-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice.

Suppola S, Heikkinen S, Parkkinen JJ, Uusi-Oukari M, Korhonen VP, Keinänen T, Alhonen L, Jänne J.

Biochem J. 2001 Sep 1;358(Pt 2):343-8.

19.

Effect of expression of human spermidine/spermine N1-acetyltransferase in Escherichia coli.

Parry L, Lopez-Ballester J, Wiest L, Pegg AE.

Biochemistry. 1995 Feb 28;34(8):2701-9.

PMID:
7873553
20.

Polyamine-regulated unproductive splicing and translation of spermidine/spermine N1-acetyltransferase.

Hyvönen MT, Uimari A, Keinänen TA, Heikkinen S, Pellinen R, Wahlfors T, Korhonen A, Närvänen A, Wahlfors J, Alhonen L, Jänne J.

RNA. 2006 Aug;12(8):1569-82. Epub 2006 Jun 29.

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