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Items: 1 to 20 of 76

1.

Do age-related changes in DNA methylation play a role in the development of age-related diseases?

van Otterdijk SD, Mathers JC, Strathdee G.

Biochem Soc Trans. 2013 Jun;41(3):803-7. doi: 10.1042/BST20120358. Review.

PMID:
23697941
2.

Aberrant methylation and silencing of ARHI, an imprinted tumor suppressor gene in which the function is lost in breast cancers.

Yuan J, Luo RZ, Fujii S, Wang L, Hu W, Andreeff M, Pan Y, Kadota M, Oshimura M, Sahin AA, Issa JP, Bast RC Jr, Yu Y.

Cancer Res. 2003 Jul 15;63(14):4174-80.

3.

Reconfiguration of DNA methylation in aging.

Zampieri M, Ciccarone F, Calabrese R, Franceschi C, Bürkle A, Caiafa P.

Mech Ageing Dev. 2015 Nov;151:60-70. doi: 10.1016/j.mad.2015.02.002. Epub 2015 Feb 20. Review.

4.

DNA methylation abnormalities at gene promoters are extensive and variable in the elderly and phenocopy cancer cells.

Gautrey HE, van Otterdijk SD, Cordell HJ; Newcastle 85+ Study Core Team, Mathers JC, Strathdee G.

FASEB J. 2014 Jul;28(7):3261-72. doi: 10.1096/fj.13-246173. Epub 2014 May 22.

5.

Distinct DNA methylation changes highly correlated with chronological age in the human brain.

Hernandez DG, Nalls MA, Gibbs JR, Arepalli S, van der Brug M, Chong S, Moore M, Longo DL, Cookson MR, Traynor BJ, Singleton AB.

Hum Mol Genet. 2011 Mar 15;20(6):1164-72. doi: 10.1093/hmg/ddq561. Epub 2011 Jan 7.

6.

CpG island methylator phenotypes in aging and cancer.

Toyota M, Issa JP.

Semin Cancer Biol. 1999 Oct;9(5):349-57. Review.

PMID:
10547343
7.

Infrequent occurrence of age-dependent changes in CpG island methylation as detected by restriction landmark genome scanning.

Tra J, Kondo T, Lu Q, Kuick R, Hanash S, Richardson B.

Mech Ageing Dev. 2002 Sep;123(11):1487-503.

PMID:
12425956
8.

Association of reduced type IX collagen gene expression in human osteoarthritic chondrocytes with epigenetic silencing by DNA hypermethylation.

Imagawa K, de Andrés MC, Hashimoto K, Itoi E, Otero M, Roach HI, Goldring MB, Oreffo RO.

Arthritis Rheumatol. 2014 Nov;66(11):3040-51. doi: 10.1002/art.38774.

9.

DNA methylation directly silences genes with non-CpG island promoters and establishes a nucleosome occupied promoter.

Han H, Cortez CC, Yang X, Nichols PW, Jones PA, Liang G.

Hum Mol Genet. 2011 Nov 15;20(22):4299-310. doi: 10.1093/hmg/ddr356. Epub 2011 Aug 11.

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12.

Cell type-specific methylation of an intronic CpG island controls expression of the MCJ gene.

Strathdee G, Davies BR, Vass JK, Siddiqui N, Brown R.

Carcinogenesis. 2004 May;25(5):693-701. Epub 2004 Jan 16.

PMID:
14729589
13.

Aging, methylation and cancer.

Ahuja N, Issa JP.

Histol Histopathol. 2000 Jul;15(3):835-42. Review.

PMID:
10963127
14.

Age-related DNA methylation changes in normal human prostate tissues.

Kwabi-Addo B, Chung W, Shen L, Ittmann M, Wheeler T, Jelinek J, Issa JP.

Clin Cancer Res. 2007 Jul 1;13(13):3796-802.

15.

Age-associated methylation change of TAP1 promoter in piglet.

Dong W, Yin X, Sun L, Wang J, Sun S, Zhu G, Wu S, Bao W.

Gene. 2015 Nov 15;573(1):70-4. doi: 10.1016/j.gene.2015.07.026. Epub 2015 Jul 11.

PMID:
26169022
16.

Genome-wide DNA methylation changes with age in disease-free human skeletal muscle.

Zykovich A, Hubbard A, Flynn JM, Tarnopolsky M, Fraga MF, Kerksick C, Ogborn D, MacNeil L, Mooney SD, Melov S.

Aging Cell. 2014 Apr;13(2):360-6. doi: 10.1111/acel.12180. Epub 2013 Dec 2.

17.

Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation.

Liu Y, Balaraman Y, Wang G, Nephew KP, Zhou FC.

Epigenetics. 2009 Oct 1;4(7):500-11.

18.

Methylomics in psychiatry: Modulation of gene-environment interactions may be through DNA methylation.

Abdolmaleky HM, Smith CL, Faraone SV, Shafa R, Stone W, Glatt SJ, Tsuang MT.

Am J Med Genet B Neuropsychiatr Genet. 2004 May 15;127B(1):51-9.

PMID:
15108180
19.

Monitoring methylation changes in cancer.

Beier V, Mund C, Hoheisel JD.

Adv Biochem Eng Biotechnol. 2007;104:1-11. Review.

PMID:
17290816

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