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Items: 1 to 20 of 83

1.

APC(CDH1) targets MgcRacGAP for destruction in the late M phase.

Nishimura K, Oki T, Kitaura J, Kuninaka S, Saya H, Sakaue-Sawano A, Miyawaki A, Kitamura T.

PLoS One. 2013 May 16;8(5):e63001. doi: 10.1371/journal.pone.0063001. Print 2013. Erratum in: PLoS One. 2014;9(3):e89706.

2.

APC(cdh1) mediates degradation of the oncogenic Rho-GEF Ect2 after mitosis.

Liot C, Seguin L, Siret A, Crouin C, Schmidt S, Bertoglio J.

PLoS One. 2011;6(8):e23676. doi: 10.1371/journal.pone.0023676. Epub 2011 Aug 19.

3.

A GTPase-activating protein binds STAT3 and is required for IL-6-induced STAT3 activation and for differentiation of a leukemic cell line.

Tonozuka Y, Minoshima Y, Bao YC, Moon Y, Tsubono Y, Hatori T, Nakajima H, Nosaka T, Kawashima T, Kitamura T.

Blood. 2004 Dec 1;104(12):3550-7. Epub 2004 Jul 29.

4.

CUX1 and E2F1 regulate coordinated expression of the mitotic complex genes Ect2, MgcRacGAP, and MKLP1 in S phase.

Seguin L, Liot C, Mzali R, Harada R, Siret A, Nepveu A, Bertoglio J.

Mol Cell Biol. 2009 Jan;29(2):570-81. doi: 10.1128/MCB.01275-08. Epub 2008 Nov 17.

5.

Role of MgcRacGAP/Cyk4 as a regulator of the small GTPase Rho family in cytokinesis and cell differentiation.

Kitamura T, Kawashima T, Minoshima Y, Tonozuka Y, Hirose K, Nosaka T.

Cell Struct Funct. 2001 Dec;26(6):645-51.

6.

MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody.

Hirose K, Kawashima T, Iwamoto I, Nosaka T, Kitamura T.

J Biol Chem. 2001 Feb 23;276(8):5821-8. Epub 2000 Nov 20.

7.

Degradation of human RAP80 is cell cycle regulated by Cdc20 and Cdh1 ubiquitin ligases.

Cho HJ, Lee EH, Han SH, Chung HJ, Jeong JH, Kwon J, Kim H.

Mol Cancer Res. 2012 May;10(5):615-25. doi: 10.1158/1541-7786.MCR-11-0481. Epub 2012 Mar 16.

8.

Mammalian Cdh1/Fzr mediates its own degradation.

Listovsky T, Oren YS, Yudkovsky Y, Mahbubani HM, Weiss AM, Lebendiker M, Brandeis M.

EMBO J. 2004 Apr 7;23(7):1619-26. Epub 2004 Mar 18.

9.

Regulation of cytokinesis by mgcRacGAP in B lymphocytes is independent of GAP activity.

Yamada T, Hikida M, Kurosaki T.

Exp Cell Res. 2006 Nov 1;312(18):3517-25. Epub 2006 Aug 12.

PMID:
16959247
10.

Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis.

Minoshima Y, Kawashima T, Hirose K, Tonozuka Y, Kawajiri A, Bao YC, Deng X, Tatsuka M, Narumiya S, May WS Jr, Nosaka T, Semba K, Inoue T, Satoh T, Inagaki M, Kitamura T.

Dev Cell. 2003 Apr;4(4):549-60.

11.

Interplay between Cdh1 and JNK activity during the cell cycle.

Gutierrez GJ, Tsuji T, Chen M, Jiang W, Ronai ZA.

Nat Cell Biol. 2010 Jul;12(7):686-95. doi: 10.1038/ncb2071. Epub 2010 Jun 27.

12.

Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors.

Kawashima T, Bao YC, Nomura Y, Moon Y, Tonozuka Y, Minoshima Y, Hatori T, Tsuchiya A, Kiyono M, Nosaka T, Nakajima H, Williams DA, Kitamura T.

J Cell Biol. 2006 Dec 18;175(6):937-46.

13.

Rho family GTPase Rnd2 interacts and co-localizes with MgcRacGAP in male germ cells.

Naud N, Touré A, Liu J, Pineau C, Morin L, Dorseuil O, Escalier D, Chardin P, Gacon G.

Biochem J. 2003 May 15;372(Pt 1):105-12.

14.

Crystal structure of GTPase-activating domain from human MgcRacGAP.

Matsuura A, Lee HH.

Biochem Biophys Res Commun. 2013 Jun 7;435(3):367-72. doi: 10.1016/j.bbrc.2013.04.094. Epub 2013 May 7.

PMID:
23665020
15.

MgcRacGAP regulates cortical activity through RhoA during cytokinesis.

Lee JS, Kamijo K, Ohara N, Kitamura T, Miki T.

Exp Cell Res. 2004 Feb 15;293(2):275-82.

PMID:
14729465
16.

Constitutive phosphorylation of a Rac GAP MgcRacGAP is implicated in v-Src-induced transformation of NIH3T3 cells.

Doki N, Kawashima T, Nomura Y, Tsuchiya A, Oneyama C, Akagi T, Nojima Y, Kitamura T.

Cancer Sci. 2009 Sep;100(9):1675-9. doi: 10.1111/j.1349-7006.2009.01235.x. Epub 2009 May 31.

17.
19.

MgcRacGAP, a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotundRacGAP gene product, is expressed in male germ cells.

Touré A, Dorseuil O, Morin L, Timmons P, Jégou B, Reibel L, Gacon G.

J Biol Chem. 1998 Mar 13;273(11):6019-23.

20.

MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity.

van Adrichem AJ, Wennerberg K.

FEBS Lett. 2015 Dec 21;589(24 Pt B):3859-65. doi: 10.1016/j.febslet.2015.11.013. Epub 2015 Nov 19.

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