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Items: 1 to 20 of 96

1.

Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats.

Kaminsky SM, Quach L, Chen S, Pierre-Destine L, Van de Graaf B, Monette S, Rosenberg JB, De BP, Sondhi D, Hackett NR, Mezey JG, Rosengart TK, Crystal RG.

Hum Gene Ther Clin Dev. 2013 Mar;24(1):38-46. doi: 10.1089/humc.2013.054.

PMID:
23692382
2.
3.

Salvage angiogenesis induced by adenovirus-mediated gene transfer of vascular endothelial growth factor protects against ischemic vascular occlusion.

Mack CA, Magovern CJ, Budenbender KT, Patel SR, Schwarz EA, Zanzonico P, Ferris B, Sanborn T, Isom P, Ferris B, Sanborn T, Isom OW, Crystal RG, Rosengart TK.

J Vasc Surg. 1998 Apr;27(4):699-709.

4.

Safety of direct myocardial administration of an adenovirus vector encoding vascular endothelial growth factor 121.

Patel SR, Lee LY, Mack CA, Polce DR, El-Sawy T, Hackett NR, Ilercil A, Jones EC, Hahn RT, Isom OW, Rosengart TK, Crystal RG.

Hum Gene Ther. 1999 May 20;10(8):1331-48.

PMID:
10365664
5.

Adenoviral-mediated transfer of vascular endothelial growth factor 121 cDNA enhances myocardial perfusion and exercise performance in the nonischemic state.

Schalch P, Rahman GF, Patejunas G, Goldschmidt RA, Carbray J, Retuerto MA, Kim D, Esser K, Crystal RG, Rosengart TK.

J Thorac Cardiovasc Surg. 2004 Feb;127(2):535-40.

7.

Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart.

Mack CA, Patel SR, Schwarz EA, Zanzonico P, Hahn RT, Ilercil A, Devereux RB, Goldsmith SJ, Christian TF, Sanborn TA, Kovesdi I, Hackett N, Isom OW, Crystal RG, Rosengart TK.

J Thorac Cardiovasc Surg. 1998 Jan;115(1):168-76; discussion 176-7.

9.

Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: a phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment.

Stewart DJ, Hilton JD, Arnold JM, Gregoire J, Rivard A, Archer SL, Charbonneau F, Cohen E, Curtis M, Buller CE, Mendelsohn FO, Dib N, Page P, Ducas J, Plante S, Sullivan J, Macko J, Rasmussen C, Kessler PD, Rasmussen HS.

Gene Ther. 2006 Nov;13(21):1503-11. Epub 2006 Jun 22.

PMID:
16791287
10.

Direct in vivo gene transfer to canine myocardium using a replication-deficient adenovirus vector.

Magovern CJ, Mack CA, Zhang J, Hahn RT, Ko W, Isom OW, Crystal RG, Rosengart TK.

Ann Thorac Surg. 1996 Aug;62(2):425-33; discussion 433-4.

PMID:
8694601
11.

Structural stability of neoangiogenic intramyocardial microvessels supports functional recovery in chronic ischemic myocardium.

Shim WS, Lim SY, Li SQ, Gu Y, Ong HC, Song IC, Chuah SC, Wong P.

J Mol Cell Cardiol. 2008 Jul;45(1):70-80. doi: 10.1016/j.yjmcc.2008.04.007. Epub 2008 Apr 27.

PMID:
18514708
12.

Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121.

Lee LY, Patel SR, Hackett NR, Mack CA, Polce DR, El-Sawy T, Hachamovitch R, Zanzonico P, Sanborn TA, Parikh M, Isom OW, Crystal RG, Rosengart TK.

Ann Thorac Surg. 2000 Jan;69(1):14-23; discussion 23-4.

PMID:
10654479
13.

Evaluation of angiogenesis and side effects in ischemic rabbit hindlimbs after intramuscular injection of adenoviral vectors encoding VEGF and LacZ.

Vajanto I, Rissanen TT, Rutanen J, Hiltunen MO, Tuomisto TT, Arve K, Närvänen O, Manninen H, Räsänen H, Hippeläinen M, Alhava E, Ylä-Herttuala S.

J Gene Med. 2002 Jul-Aug;4(4):371-80.

PMID:
12124979
14.

Cellular, but not direct, adenoviral delivery of vascular endothelial growth factor results in improved left ventricular function and neovascularization in dilated ischemic cardiomyopathy.

Askari A, Unzek S, Goldman CK, Ellis SG, Thomas JD, DiCorleto PE, Topol EJ, Penn MS.

J Am Coll Cardiol. 2004 May 19;43(10):1908-14.

15.

"Triplet" polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors.

Mathison M, Singh VP, Gersch RP, Ramirez MO, Cooney A, Kaminsky SM, Chiuchiolo MJ, Nasser A, Yang J, Crystal RG, Rosengart TK.

J Thorac Cardiovasc Surg. 2014 Oct;148(4):1656-1664.e2. doi: 10.1016/j.jtcvs.2014.03.033. Epub 2014 Mar 27.

16.

[Recombinant adeno-associated viral vector 2-mediated gene transfer of VEGF165 improved porcine chronic myocardial ischemia].

Deng XL, Wu XB, Jiang J, Guo YH, Yan H, Shi B, Chen M, Yang Y, Wang JC, Wang XY, Qiu JX, Gao L, Gao W.

Zhonghua Xin Xue Guan Bing Za Zhi. 2005 Aug;33(8):732-7. Chinese.

PMID:
16188064
17.

The effects of VEGF-R1 and VEGF-R2 ligands on angiogenic responses and left ventricular function in mice.

Huusko J, Merentie M, Dijkstra MH, Ryhänen MM, Karvinen H, Rissanen TT, Vanwildemeersch M, Hedman M, Lipponen J, Heinonen SE, Eriksson U, Shibuya M, Ylä-Herttuala S.

Cardiovasc Res. 2010 Apr 1;86(1):122-30. doi: 10.1093/cvr/cvp382. Epub 2009 Dec 2.

PMID:
19955220
18.

Angiopoietin-1 promotes functional neovascularization that relieves ischemia by improving regional reperfusion in a swine chronic myocardial ischemia model.

Shim WS, Li W, Zhang L, Li S, Ong HC, Song IC, Bapna A, Ge R, Lim YT, Chuah SC, Sim EK, Wong P.

J Biomed Sci. 2006 Jul;13(4):579-91. Epub 2006 Mar 18.

PMID:
16547766
19.

AdVEGF-B186 and AdVEGF-DΔNΔC induce angiogenesis and increase perfusion in porcine myocardium.

Nurro J, Halonen PJ, Kuivanen A, Tarkia M, Saraste A, Honkonen K, Lähteenvuo J, Rissanen TT, Knuuti J, Ylä-Herttuala S.

Heart. 2016 Nov 1;102(21):1716-1720. doi: 10.1136/heartjnl-2016-309373. Epub 2016 May 12.

PMID:
27173504
20.

Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart.

Rutanen J, Rissanen TT, Markkanen JE, Gruchala M, Silvennoinen P, Kivelä A, Hedman A, Hedman M, Heikura T, Ordén MR, Stacker SA, Achen MG, Hartikainen J, Ylä-Herttuala S.

Circulation. 2004 Mar 2;109(8):1029-35. Epub 2004 Feb 16.

PMID:
14967735

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