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Items: 1 to 20 of 337

1.

Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression.

Yamaguchi T, Kishi A, Osaki M, Morikawa H, Prieto-Martin P, Wing K, Saito T, Sakaguchi S.

Proc Natl Acad Sci U S A. 2013 Jun 4;110(23):E2116-25. doi: 10.1073/pnas.1307185110. Epub 2013 May 20.

2.

CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire.

Verhagen J, Genolet R, Britton GJ, Stevenson BJ, Sabatos-Peyton CA, Dyson J, Luescher IF, Wraith DC.

Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):E221-30. doi: 10.1073/pnas.1208573110. Epub 2012 Dec 24.

3.

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation.

Onishi Y, Fehervari Z, Yamaguchi T, Sakaguchi S.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):10113-8. doi: 10.1073/pnas.0711106105. Epub 2008 Jul 17.

4.

Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance.

Itoh M, Takahashi T, Sakaguchi N, Kuniyasu Y, Shimizu J, Otsuka F, Sakaguchi S.

J Immunol. 1999 May 1;162(9):5317-26.

5.

Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4.

Pletinckx K, Vaeth M, Schneider T, Beyersdorf N, Hünig T, Berberich-Siebelt F, Lutz MB.

Eur J Immunol. 2015 Feb;45(2):480-91. doi: 10.1002/eji.201444991. Epub 2014 Dec 2.

6.

CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice.

Kolar P, Knieke K, Hegel JK, Quandt D, Burmester GR, Hoff H, Brunner-Weinzierl MC.

Arthritis Rheum. 2009 Jan;60(1):123-32. doi: 10.1002/art.24181.

7.

Id1 expression promotes T regulatory cell differentiation by facilitating TCR costimulation.

Liu C, Wang HC, Yu S, Jin R, Tang H, Liu YF, Ge Q, Sun XH, Zhang Y.

J Immunol. 2014 Jul 15;193(2):663-672. doi: 10.4049/jimmunol.1302554. Epub 2014 Jun 11.

8.

Adaptation of TCR repertoires to self-peptides in regulatory and nonregulatory CD4+ T cells.

Wong J, Obst R, Correia-Neves M, Losyev G, Mathis D, Benoist C.

J Immunol. 2007 Jun 1;178(11):7032-41.

9.

CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells.

Zheng Y, Manzotti CN, Liu M, Burke F, Mead KI, Sansom DM.

J Immunol. 2004 Mar 1;172(5):2778-84.

10.

Expression of tumor necrosis factor-α induced protein 8 like-2 contributes to the immunosuppressive property of CD4(+)CD25(+) regulatory T cells in mice.

Luan YY, Yao YM, Zhang L, Dong N, Zhang QH, Yu Y, Sheng ZY.

Mol Immunol. 2011 Oct;49(1-2):219-26. doi: 10.1016/j.molimm.2011.08.016. Epub 2011 Oct 2.

PMID:
21963221
11.

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

Takahashi T, Tagami T, Yamazaki S, Uede T, Shimizu J, Sakaguchi N, Mak TW, Sakaguchi S.

J Exp Med. 2000 Jul 17;192(2):303-10.

12.

Characteristics of TCR/CD3 complex CD3{varepsilon} chains of regulatory CD4+ T (Treg) lymphocytes: role in Treg differentiation in vitro and impact on Treg in vivo.

Rojo JM, Ojeda G, Acosta YY, Montes-Casado M, Criado G, Portolés P.

J Leukoc Biol. 2014 Mar;95(3):441-50. doi: 10.1189/jlb.1112584. Epub 2013 Nov 8.

PMID:
24212096
13.

Interleukin-7 matures suppressive CD127(+) forkhead box P3 (FoxP3)(+) T cells into CD127(-) CD25(high) FoxP3(+) regulatory T cells.

Di Caro V, D'Anneo A, Phillips B, Engman C, Harnaha J, Lakomy R, Styche A, Trucco M, Giannoukakis N.

Clin Exp Immunol. 2011 Jul;165(1):60-76. doi: 10.1111/j.1365-2249.2011.04334.x. Epub 2011 Mar 17.

14.

Targeting CD28, CTLA-4 and PD-L1 costimulation differentially controls immune synapses and function of human regulatory and conventional T-cells.

Dilek N, Poirier N, Hulin P, Coulon F, Mary C, Ville S, Vie H, Clémenceau B, Blancho G, Vanhove B.

PLoS One. 2013 Dec 23;8(12):e83139. doi: 10.1371/journal.pone.0083139. eCollection 2013.

15.

Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection.

Ribot J, Enault G, Pilipenko S, Huchenq A, Calise M, Hudrisier D, Romagnoli P, van Meerwijk JP.

J Immunol. 2007 Nov 15;179(10):6741-8.

16.

Ligation of cytotoxic T lymphocyte antigen-4 to T cell receptor inhibits T cell activation and directs differentiation into Foxp3+ regulatory T cells.

Karman J, Jiang JL, Gumlaw N, Zhao H, Campos-Rivera J, Sancho J, Zhang J, Jiang C, Cheng SH, Zhu Y.

J Biol Chem. 2012 Mar 30;287(14):11098-107. doi: 10.1074/jbc.M111.283705. Epub 2012 Feb 15.

17.

PTD-hFOXP3 protein acts as an immune regulator to convert human CD4(+)CD25(-) T cells to regulatory T-like cells.

Liu X, Xu X, Lin X, Tian Y, Ji B, Xia S, Xu S, Yin Q, Zhang M, Jiao Z, Wang S, Xu H, Shao Q.

J Cell Biochem. 2012 Dec;113(12):3797-809. doi: 10.1002/jcb.24255.

PMID:
22806628
18.

Increased numbers and suppressive activity of regulatory CD25(+)CD4(+) T lymphocytes in the absence of CD4 engagement by MHC class II molecules.

Shen X, Niu C, König R.

Cell Immunol. 2013 Apr;282(2):117-28. doi: 10.1016/j.cellimm.2013.05.002. Epub 2013 May 15.

PMID:
23770721
19.

CD4+CD25+ Treg derived from hepatocellular carcinoma mice inhibits tumor immunity.

Chen X, Du Y, Huang Z.

Immunol Lett. 2012 Nov-Dec;148(1):83-9. doi: 10.1016/j.imlet.2012.09.002. Epub 2012 Sep 19.

PMID:
23000301
20.

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