Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 122

1.

Structural and pharmacological characterization of novel potent and selective monoclonal antibody antagonists of glucose-dependent insulinotropic polypeptide receptor.

Ravn P, Madhurantakam C, Kunze S, Matthews E, Priest C, O'Brien S, Collinson A, Papworth M, Fritsch-Fredin M, Jermutus L, Benthem L, Gruetter M, Jackson RH.

J Biol Chem. 2013 Jul 5;288(27):19760-72. doi: 10.1074/jbc.M112.426288. Epub 2013 May 20.

2.
3.
4.

GIP(3-30)NH2 is a potent competitive antagonist of the GIP receptor and effectively inhibits GIP-mediated insulin, glucagon, and somatostatin release.

Sparre-Ulrich AH, Gabe MN, Gasbjerg LS, Christiansen CB, Svendsen B, Hartmann B, Holst JJ, Rosenkilde MM.

Biochem Pharmacol. 2017 May 1;131:78-88. doi: 10.1016/j.bcp.2017.02.012. Epub 2017 Feb 22.

5.

Identification of determinants of glucose-dependent insulinotropic polypeptide receptor that interact with N-terminal biologically active region of the natural ligand.

Yaqub T, Tikhonova IG, Lättig J, Magnan R, Laval M, Escrieut C, Boulègue C, Hewage C, Fourmy D.

Mol Pharmacol. 2010 Apr;77(4):547-58. doi: 10.1124/mol.109.060111. Epub 2010 Jan 8.

6.

Mapping interactions of gastric inhibitory polypeptide with GIPR N-terminus using NMR and molecular dynamics simulations.

Tikhele SH, Pissurlenkar RR, Srivastava S, Saran A, Coutinho EC.

J Pept Sci. 2010 Aug;16(8):383-91. doi: 10.1002/psc.1250.

PMID:
20607844
7.

Internalization and desensitization of the human glucose-dependent-insulinotropic receptor is affected by N-terminal acetylation of the agonist.

Ismail S, Dubois-Vedrenne I, Laval M, Tikhonova IG, D'Angelo R, Sanchez C, Clerc P, Gherardi MJ, Gigoux V, Magnan R, Fourmy D.

Mol Cell Endocrinol. 2015 Oct 15;414:202-15. doi: 10.1016/j.mce.2015.07.001. Epub 2015 Jul 28.

PMID:
26225752
8.

Tyr1 and Ile7 of glucose-dependent insulinotropic polypeptide (GIP) confer differential ligand selectivity toward GIP and glucagon-like peptide-1 receptors.

Moon MJ, Kim HY, Kim SG, Park J, Choi DS, Hwang JI, Seong JY.

Mol Cells. 2010 Aug;30(2):149-54. doi: 10.1007/s10059-010-0100-5. Epub 2010 Aug 19.

9.

Glucose-dependent insulinotropic polypeptide (GIP) and its receptor (GIPR): cellular localization, lesion-affected expression, and impaired regenerative axonal growth.

Buhren BA, Gasis M, Thorens B, Müller HW, Bosse F.

J Neurosci Res. 2009 Jun;87(8):1858-70. doi: 10.1002/jnr.22001.

PMID:
19170165
10.

The GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively.

Al-Sabah S, Al-Fulaij M, Shaaban G, Ahmed HA, Mann RJ, Donnelly D, Bünemann M, Krasel C.

PLoS One. 2014 Sep 5;9(9):e106890. doi: 10.1371/journal.pone.0106890. eCollection 2014.

11.

Differential importance of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide 1 receptor signaling for beta cell survival in mice.

Maida A, Hansotia T, Longuet C, Seino Y, Drucker DJ.

Gastroenterology. 2009 Dec;137(6):2146-57. doi: 10.1053/j.gastro.2009.09.004. Epub 2009 Sep 17.

PMID:
19766644
12.

Disruption of GIP/GIPR axis in human adipose tissue is linked to obesity and insulin resistance.

Ceperuelo-Mallafré V, Duran X, Pachón G, Roche K, Garrido-Sánchez L, Vilarrasa N, Tinahones FJ, Vicente V, Pujol J, Vendrell J, Fernández-Veledo S.

J Clin Endocrinol Metab. 2014 May;99(5):E908-19. doi: 10.1210/jc.2013-3350. Epub 2014 Feb 10.

13.

Conformational, receptor interaction and alanine scan studies of glucose-dependent insulinotropic polypeptide.

Venneti KC, Malthouse JP, O'Harte FP, Hewage CM.

Biochim Biophys Acta. 2011 Jul;1814(7):882-8. doi: 10.1016/j.bbapap.2011.04.002. Epub 2011 Apr 27.

PMID:
21539943
14.

A novel GIP receptor splice variant influences GIP sensitivity of pancreatic beta-cells in obese mice.

Harada N, Yamada Y, Tsukiyama K, Yamada C, Nakamura Y, Mukai E, Hamasaki A, Liu X, Toyoda K, Seino Y, Inagaki N.

Am J Physiol Endocrinol Metab. 2008 Jan;294(1):E61-8. Epub 2007 Oct 30.

15.

A naturally occurring GIP receptor variant undergoes enhanced agonist-induced desensitization, which impairs GIP control of adipose insulin sensitivity.

Mohammad S, Patel RT, Bruno J, Panhwar MS, Wen J, McGraw TE.

Mol Cell Biol. 2014 Oct 1;34(19):3618-29. doi: 10.1128/MCB.00256-14. Epub 2014 Jul 21.

16.

Functional elements of the gastric inhibitory polypeptide receptor: Comparison between secretin- and rhodopsin-like G protein-coupled receptors.

Cordomí A, Ismail S, Matsoukas MT, Escrieut C, Gherardi MJ, Pardo L, Fourmy D.

Biochem Pharmacol. 2015 Aug 1;96(3):237-46. doi: 10.1016/j.bcp.2015.05.015. Epub 2015 Jun 1.

PMID:
26043830
17.

TCF1 links GIPR signaling to the control of beta cell function and survival.

Campbell JE, Ussher JR, Mulvihill EE, Kolic J, Baggio LL, Cao X, Liu Y, Lamont BJ, Morii T, Streutker CJ, Tamarina N, Philipson LH, Wrana JL, MacDonald PE, Drucker DJ.

Nat Med. 2016 Jan;22(1):84-90. doi: 10.1038/nm.3997. Epub 2015 Dec 7.

PMID:
26642437
18.

[Gastric inhibitory polypeptide (GIP) and GIP receptor (GIPR)].

Yasuda K, Seino Y.

Nihon Rinsho. 1996 Apr;54(4):1078-82. Review. Japanese.

PMID:
8920677
19.

A novel pathway for regulation of glucose-dependent insulinotropic polypeptide (GIP) receptor expression in beta cells.

Lynn FC, Thompson SA, Pospisilik JA, Ehses JA, Hinke SA, Pamir N, McIntosh CH, Pederson RA.

FASEB J. 2003 Jan;17(1):91-3. Epub 2002 Nov 15.

PMID:
12475913
20.

Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis.

Pamir N, Lynn FC, Buchan AM, Ehses J, Hinke SA, Pospisilik JA, Miyawaki K, Yamada Y, Seino Y, McIntosh CH, Pederson RA.

Am J Physiol Endocrinol Metab. 2003 May;284(5):E931-9. Epub 2003 Jan 21.

Supplemental Content

Support Center