Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 103

1.
2.

A series of novel neuroprotective blood brain barrier penetrating flavonoid drugs to treat acute ischemic stroke.

Lapchak PA.

Curr Pharm Des. 2012;18(25):3694-703. Review. Erratum in: Curr Pharm Des. 2013;19(3):527.

PMID:
22574983
3.

A novel approach to screening for new neuroprotective compounds for the treatment of stroke.

Maher P, Salgado KF, Zivin JA, Lapchak PA.

Brain Res. 2007 Oct 10;1173:117-25.

4.

Clinical trials in acute ischemic stroke.

Kikuchi K, Tanaka E, Murai Y, Tancharoen S.

CNS Drugs. 2014 Oct;28(10):929-38. doi: 10.1007/s40263-014-0199-6. Review.

PMID:
25160686
5.

De-Risking of Stilbazulenyl Nitrone (STAZN), a Lipophilic Nitrone to Treat Stroke Using a Unique Panel of In Vitro Assays.

Lapchak PA, Schubert DR, Maher PA.

Transl Stroke Res. 2011 Jun;2(2):209-17. doi: 10.1007/s12975-011-0071-7.

6.

Neuroprotective and neurotrophic curcuminoids to treat stroke: a translational perspective.

Lapchak PA.

Expert Opin Investig Drugs. 2011 Jan;20(1):13-22. doi: 10.1517/13543784.2011.542410. Review.

PMID:
21158690
7.

Neuroprotection in cerebral ischaemia: facts and fancies--the need for new approaches.

Wahlgren NG, Ahmed N.

Cerebrovasc Dis. 2004;17 Suppl 1:153-66. Review.

PMID:
14694293
8.

Α-aryl-N-alkyl nitrones, as potential agents for stroke treatment: synthesis, theoretical calculations, antioxidant, anti-inflammatory, neuroprotective, and brain-blood barrier permeability properties.

Chioua M, Sucunza D, Soriano E, Hadjipavlou-Litina D, Alcázar A, Ayuso I, Oset-Gasque MJ, González MP, Monjas L, Rodríguez-Franco MI, Marco-Contelles J, Samadi A.

J Med Chem. 2012 Jan 12;55(1):153-68. doi: 10.1021/jm201105a.

PMID:
22126405
9.

The Natural Flavonoid Pinocembrin: Molecular Targets and Potential Therapeutic Applications.

Lan X, Wang W, Li Q, Wang J.

Mol Neurobiol. 2016 Apr;53(3):1794-801. doi: 10.1007/s12035-015-9125-2. Review.

PMID:
25744566
10.

HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved.

Tolosa L, Gómez-Lechón MJ, Pérez-Cataldo G, Castell JV, Donato MT.

Arch Toxicol. 2013 Jun;87(6):1115-27. doi: 10.1007/s00204-013-1012-x.

PMID:
23397584
11.

Design, synthesis and biological evaluation of tricyclic diterpene derivatives as novel neuroprotective agents against ischemic brain injury.

Wang YY, Gao YX, Gao W, Xu Y, Xu YZ, Wang YJ, Chang S, Yu LG, Zhang LY, Liao H, Yang LF, Pang T, Qiu WW.

Eur J Med Chem. 2015 Oct 20;103:396-408. doi: 10.1016/j.ejmech.2015.08.057.

PMID:
26375352
12.

Evaluation of the Vitotox and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development.

Westerink WM, Stevenson JC, Lauwers A, Griffioen G, Horbach GJ, Schoonen WG.

Mutat Res. 2009 May 31;676(1-2):113-30. doi: 10.1016/j.mrgentox.2009.04.008.

PMID:
19393335
13.

Biopharmaceutical characterization of decursin and their derivatives for drug discovery.

Mahat B, Chae JW, Baek IH, Song GY, Song JS, Ma JY, Kwon KI.

Drug Dev Ind Pharm. 2013 Oct;39(10):1523-30. doi: 10.3109/03639045.2012.717296.

PMID:
23003006
14.

Creatinyl amino acids: new hybrid compounds with neuroprotective activity.

Burov S, Leko M, Dorosh M, Dobrodumov A, Veselkina O.

J Pept Sci. 2011 Sep;17(9):620-6. doi: 10.1002/psc.1379.

PMID:
21644247
15.

J-147 a Novel Hydrazide Lead Compound to Treat Neurodegeneration: CeeTox Safety and Genotoxicity Analysis.

Lapchak PA, Bombien R, Rajput PS.

J Neurol Neurophysiol. 2013 Aug;4(3). pii: 158.

16.
17.
18.

A pharmacological screening approach for discovery of neuroprotective compounds in ischemic stroke.

Beraki S, Litrus L, Soriano L, Monbureau M, To LK, Braithwaite SP, Nikolich K, Urfer R, Oksenberg D, Shamloo M.

PLoS One. 2013 Jul 18;8(7):e69233. doi: 10.1371/journal.pone.0069233.

19.

Transport of cryptotanshinone, a major active triterpenoid in Salvia miltiorrhiza Bunge widely used in the treatment of stroke and Alzheimer's disease, across the blood-brain barrier.

Yu XY, Lin SG, Chen X, Zhou ZW, Liang J, Duan W, Chowbay B, Wen JY, Chan E, Cao J, Li CG, Zhou SF.

Curr Drug Metab. 2007 May;8(4):365-78.

PMID:
17504224

Supplemental Content

Support Center