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Items: 1 to 20 of 210

1.

Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.

Mathews RJ, Robinson JI, Battellino M, Wong C, Taylor JC; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Eyre S, Churchman SM, Wilson AG, Isaacs JD, Hyrich K, Barton A, Plant D, Savic S, Cook GP, Sarzi-Puttini P, Emery P, Barrett JH, Morgan AW, McDermott MF.

Ann Rheum Dis. 2014 Jun;73(6):1202-10. doi: 10.1136/annrheumdis-2013-203276. Epub 2013 May 17.

PMID:
23687262
2.

Association study of CARD8 (p.C10X) and NLRP3 (p.Q705K) variants with rheumatoid arthritis in French and Tunisian populations.

Ben Hamad M, Cornelis F, Marzouk S, Chabchoub G, Bahloul Z, Rebai A, Fakhfakh F, Ayadi H, Petit-Teixeira E, Maalej A.

Int J Immunogenet. 2012 Apr;39(2):131-6. doi: 10.1111/j.1744-313X.2011.01070.x. Epub 2011 Dec 1.

PMID:
22128899
3.

Anti-TNF treatment response in rheumatoid arthritis patients is associated with genetic variation in the NLRP3-inflammasome.

Sode J, Vogel U, Bank S, Andersen PS, Thomsen MK, Hetland ML, Locht H, Heegaard NH, Andersen V.

PLoS One. 2014 Jun 26;9(6):e100361. doi: 10.1371/journal.pone.0100361. eCollection 2014.

4.

CARD8 p.C10X polymorphism is associated with inflammatory activity in early rheumatoid arthritis.

Kastbom A, Johansson M, Verma D, Söderkvist P, Rantapää-Dahlqvist S.

Ann Rheum Dis. 2010 Apr;69(4):723-6. doi: 10.1136/ard.2008.106989. Epub 2009 May 13.

PMID:
19443463
5.

Genetic variants in CARD8 but not in NLRP3 are associated with ankylosing spondylitis.

Kastbom A, Klingberg E, Verma D, Carlsten H, Forsblad-d'Elia H, Wesamaa J, Cedergren J, Eriksson P, Söderkvist P.

Scand J Rheumatol. 2013;42(6):465-8. doi: 10.3109/03009742.2013.779020. Epub 2013 Apr 2.

PMID:
23547871
6.

Association of NLRP3 and CARD8 genetic polymorphisms with juvenile idiopathic arthritis in a Taiwanese population.

Yang CA, Huang ST, Chiang BL.

Scand J Rheumatol. 2014;43(2):146-52. doi: 10.3109/03009742.2013.834962. Epub 2013 Dec 3.

PMID:
24295199
7.

Genetic variants within the MAP kinase signalling network and anti-TNF treatment response in rheumatoid arthritis patients.

Coulthard LR, Taylor JC, Eyre S; Biologics in Rheumatoid Arthritis Genetics and Genomics, Robinson JI, Wilson AG, Isaacs JD, Hyrich K, Emery P, Barton A, Barrett JH, Morgan AW, McDermott MF.

Ann Rheum Dis. 2011 Jan;70(1):98-103. doi: 10.1136/ard.2010.133249. Epub 2010 Aug 30.

PMID:
20805296
8.

Genetic support for the role of the NLRP3 inflammasome in psoriasis susceptibility.

Carlström M, Ekman AK, Petersson S, Söderkvist P, Enerbäck C.

Exp Dermatol. 2012 Dec;21(12):932-7. doi: 10.1111/exd.12049.

PMID:
23171454
9.

Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NF{kappa}B signalling pathways.

Potter C, Cordell HJ, Barton A, Daly AK, Hyrich KL, Mann DA, Morgan AW, Wilson AG; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Isaacs JD.

Ann Rheum Dis. 2010 Jul;69(7):1315-20. doi: 10.1136/ard.2009.117309. Epub 2010 May 6.

PMID:
20448286
10.

Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis.

Sode J, Vogel U, Bank S, Andersen PS, Hetland ML, Locht H, Heegaard NH, Andersen V.

PLoS One. 2015 Oct 6;10(10):e0139781. doi: 10.1371/journal.pone.0139781. eCollection 2015.

11.

Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment.

Tan RJ, Gibbons LJ, Potter C, Hyrich KL, Morgan AW, Wilson AG, Isaacs JD; BRAGGSS, Barton A.

Ann Rheum Dis. 2010 Jun;69(6):1029-35. doi: 10.1136/ard.2009.118406. Epub 2010 May 5. Erratum in: Ann Rheum Dis. 2011 Aug;70(8):1519.

12.

Multiplicative interaction of functional inflammasome genetic variants in determining the risk of gout.

McKinney C, Stamp LK, Dalbeth N, Topless RK, Day RO, Kannangara DR, Williams KM, Janssen M, Jansen TL, Joosten LA, Radstake TR, Riches PL, Tausche AK, Lioté F, So A, Merriman TR.

Arthritis Res Ther. 2015 Oct 13;17:288. doi: 10.1186/s13075-015-0802-3.

13.

Polymorphisms in inflammasome' genes and susceptibility to HIV-1 infection.

Pontillo A, Oshiro TM, Girardelli M, Kamada AJ, Crovella S, Duarte AJ.

J Acquir Immune Defic Syndr. 2012 Feb 1;59(2):121-5. doi: 10.1097/QAI.0b013e3182392ebe.

PMID:
22227487
14.

Cytokine profile in a cohort of healthy blood donors carrying polymorphisms in genes encoding the NLRP3 inflammasome.

Sahdo B, Fransén K, Asfaw Idosa B, Eriksson P, Söderquist B, Kelly A, Särndahl E.

PLoS One. 2013 Oct 3;8(10):e75457. doi: 10.1371/journal.pone.0075457. eCollection 2013.

15.

Genetic Variants of the NLRP3 Inflammasome Are Associated with Stroke in Patients with Rheumatoid Arthritis.

Kastbom A, Ärlestig L, Rantapää-Dahlqvist S.

J Rheumatol. 2015 Oct;42(10):1740-5. doi: 10.3899/jrheum.141529. Epub 2015 Jul 15.

PMID:
26178285
16.

Caspase-1 mediated interleukin-18 activation in neutrophils promotes the activity of rheumatoid arthritis in a NLRP3 inflammasome independent manner.

Yang Z, Cao J, Yu C, Yang Q, Zhang Y, Han L.

Joint Bone Spine. 2016 May;83(3):282-9. doi: 10.1016/j.jbspin.2015.07.006. Epub 2016 Jan 5.

PMID:
26775759
17.

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis.

Paramel Varghese G, Folkersen L, Strawbridge RJ, Halvorsen B, Yndestad A, Ranheim T, Krohg-Sørensen K, Skjelland M, Espevik T, Aukrust P, Lengquist M, Hedin U, Jansson JH, Fransén K, Hansson GK, Eriksson P, Sirsjö A.

J Am Heart Assoc. 2016 May 20;5(5). pii: e003031. doi: 10.1161/JAHA.115.003031.

18.

Role of genetic alterations in the NLRP3 and CARD8 genes in health and disease.

Paramel GV, Sirsjö A, Fransén K.

Mediators Inflamm. 2015;2015:846782. doi: 10.1155/2015/846782. Epub 2015 Feb 18. Review.

19.

Combined polymorphisms in genes encoding the inflammasome components NALP3 and CARD8 confer susceptibility to Crohn's disease in Swedish men.

Schoultz I, Verma D, Halfvarsson J, Törkvist L, Fredrikson M, Sjöqvist U, Lördal M, Tysk C, Lerm M, Söderkvist P, Söderholm JD.

Am J Gastroenterol. 2009 May;104(5):1180-8. doi: 10.1038/ajg.2009.29. Epub 2009 Mar 24.

PMID:
19319132
20.

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