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Items: 1 to 20 of 125


Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.

Chari NS, Romano RA, Koster MI, Jaks V, Roop D, Flores ER, Teglund S, Sinha S, Gruber W, Aberger F, Medeiros LJ, Toftgard R, McDonnell TJ.

Cell Death Differ. 2013 Aug;20(8):1080-8. doi: 10.1038/cdd.2013.41. Epub 2013 May 17.


p63/p51-induced onset of keratinocyte differentiation via the c-Jun N-terminal kinase pathway is counteracted by keratinocyte growth factor.

Ogawa E, Okuyama R, Egawa T, Nagoshi H, Obinata M, Tagami H, Ikawa S, Aiba S.

J Biol Chem. 2008 Dec 5;283(49):34241-9. doi: 10.1074/jbc.M804101200. Epub 2008 Oct 10.


Dynamic life of a skin keratinocyte: an intimate tryst with the master regulator p63.

Romano RA, Sinha S.

Indian J Exp Biol. 2011 Oct;49(10):721-31. Review.


deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes.

King KE, Ponnamperuma RM, Yamashita T, Tokino T, Lee LA, Young MF, Weinberg WC.

Oncogene. 2003 Jun 5;22(23):3635-44.


Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling.

Lin C, Yao E, Wang K, Nozawa Y, Shimizu H, Johnson JR, Chen JN, Krogan NJ, Chuang PT.

Genes Dev. 2014 Nov 15;28(22):2547-63. doi: 10.1101/gad.249425.114.


Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis.

Li ZJ, Nieuwenhuis E, Nien W, Zhang X, Zhang J, Puviindran V, Wainwright BJ, Kim PC, Hui CC.

Development. 2012 Nov;139(22):4152-61. doi: 10.1242/dev.081190. Epub 2012 Oct 3.


Unique domain functions of p63 isotypes that differentially regulate distinct aspects of epidermal homeostasis.

King KE, Ponnamperuma RM, Gerdes MJ, Tokino T, Yamashita T, Baker CC, Weinberg WC.

Carcinogenesis. 2006 Jan;27(1):53-63. Epub 2005 Aug 4.


Suppressor of Fused Plays an Important Role in Regulating Mesodermal Differentiation of Murine Embryonic Stem Cells In Vivo.

Hoelzl MA, Heby-Henricson K, Bilousova G, Rozell B, Kuiper RV, Kasper M, Toftgård R, Teglund S.

Stem Cells Dev. 2015 Nov 1;24(21):2547-60. doi: 10.1089/scd.2015.0050. Epub 2015 Aug 18.


Novel mechanism of action on Hedgehog signaling by a suppressor of fused carboxy terminal variant.

Tostar U, Finta C, Rahman MF, Shimokawa T, Zaphiropoulos PG.

PLoS One. 2012;7(5):e37761. doi: 10.1371/journal.pone.0037761. Epub 2012 May 29.


Overexpression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor-null mice.

Teichert AE, Elalieh H, Elias PM, Welsh J, Bikle DD.

J Invest Dermatol. 2011 Nov;131(11):2289-97. doi: 10.1038/jid.2011.196. Epub 2011 Aug 4.


14-3-3σ and p63 play opposing roles in epidermal tumorigenesis.

Li Q, Sambandam SA, Lu HJ, Thomson A, Kim SH, Lu H, Xin Y, Lu Q.

Carcinogenesis. 2011 Dec;32(12):1782-8. doi: 10.1093/carcin/bgr207. Epub 2011 Sep 16.


Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog.

Fan H, Oro AE, Scott MP, Khavari PA.

Nat Med. 1997 Jul;3(7):788-92.


Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina.

Cwinn MA, Mazerolle C, McNeill B, Ringuette R, Thurig S, Hui CC, Wallace VA.

J Neurosci. 2011 Mar 30;31(13):5169-80. doi: 10.1523/JNEUROSCI.5495-10.2011.


Antagonistic and cooperative actions of Kif7 and Sufu define graded intracellular Gli activities in Hedgehog signaling.

Law KK, Makino S, Mo R, Zhang X, Puviindran V, Hui CC.

PLoS One. 2012;7(11):e50193. doi: 10.1371/journal.pone.0050193. Epub 2012 Nov 16.


Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused.

Cooper AF, Yu KP, Brueckner M, Brailey LL, Johnson L, McGrath JM, Bale AE.

Development. 2005 Oct;132(19):4407-17.


IKK1 control of epidermal differentiation is modulated by notch signaling.

Xin Y, Lu Q, Li Q.

Am J Pathol. 2011 Apr;178(4):1568-77. doi: 10.1016/j.ajpath.2010.12.021.


P63 deficiency: a failure of lineage commitment or stem cell maintenance?

Koster MI, Kim S, Roop DR.

J Investig Dermatol Symp Proc. 2005 Nov;10(2):118-23. Review.


Modulation of hair growth with small molecule agonists of the hedgehog signaling pathway.

Paladini RD, Saleh J, Qian C, Xu GX, Rubin LL.

J Invest Dermatol. 2005 Oct;125(4):638-46.


Sonic hedgehog induces epidermal growth factor dependent matrix infiltration in HaCaT keratinocytes.

Bigelow RL, Jen EY, Delehedde M, Chari NS, McDonnell TJ.

J Invest Dermatol. 2005 Feb;124(2):457-65.

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