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Items: 1 to 20 of 125

1.

Development of an AlphaScreen assay for discovery of inhibitors of low-affinity glycan-lectin interactions.

Yegorova S, Chavaroche AE, Rodriguez MC, Minond D, Cudic M.

Anal Biochem. 2013 Aug 15;439(2):123-31. doi: 10.1016/j.ab.2013.04.028. Epub 2013 May 16.

PMID:
23685052
2.

Development of a novel β-secretase binding assay using the AlphaScreen platform.

Ren Z, Tam D, Xu YZ, Wone D, Yuan S, Sham HL, Cheung H, Regnstrom K, Chen X, Rudolph D, Jobling MF, Artis DR, Bova MP.

J Biomol Screen. 2013 Jul;18(6):695-704. doi: 10.1177/1087057113482138. Epub 2013 Mar 29.

PMID:
23543430
3.

Ligand induced galectin-3 protein self-association.

Lepur A, Salomonsson E, Nilsson UJ, Leffler H.

J Biol Chem. 2012 Jun 22;287(26):21751-6. doi: 10.1074/jbc.C112.358002. Epub 2012 May 1.

4.

Galectins bind to the multivalent glycoprotein asialofetuin with enhanced affinities and a gradient of decreasing binding constants.

Dam TK, Gabius HJ, André S, Kaltner H, Lensch M, Brewer CF.

Biochemistry. 2005 Sep 20;44(37):12564-71.

PMID:
16156668
5.

Galectin-loaded cells as a platform for the profiling of lectin specificity by fluorescent neoglycoconjugates: a case study on galectins-1 and -3 and the impact of assay setting.

Rapoport EM, André S, Kurmyshkina OV, Pochechueva TV, Severov VV, Pazynina GV, Gabius HJ, Bovin NV.

Glycobiology. 2008 Apr;18(4):315-24. doi: 10.1093/glycob/cwn009. Epub 2008 Feb 6.

PMID:
18256179
6.

Fluorescence polarization as an analytical tool to evaluate galectin-ligand interactions.

Sörme P, Kahl-Knutsson B, Huflejt M, Nilsson UJ, Leffler H.

Anal Biochem. 2004 Nov 1;334(1):36-47.

PMID:
15464951
7.

Fluorescence-based solid-phase assays to study glycan-binding protein interactions with glycoconjugates.

Leppänen A, Cummings RD.

Methods Enzymol. 2010;478:241-64. doi: 10.1016/S0076-6879(10)78012-5.

PMID:
20816484
8.

Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides.

Rodriguez MC, Yegorova S, Pitteloud JP, Chavaroche AE, André S, Ardá A, Minond D, Jiménez-Barbero J, Gabius HJ, Cudic M.

Biochemistry. 2015 Jul 28;54(29):4462-74. doi: 10.1021/acs.biochem.5b00555. Epub 2015 Jul 20.

9.

Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans.

Stegmayr J, Lepur A, Kahl-Knutson B, Aguilar-Moncayo M, Klyosov AA, Field RA, Oredsson S, Nilsson UJ, Leffler H.

J Biol Chem. 2016 Jun 17;291(25):13318-34. doi: 10.1074/jbc.M116.721464. Epub 2016 Apr 26.

10.

Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells.

Patnaik SK, Potvin B, Carlsson S, Sturm D, Leffler H, Stanley P.

Glycobiology. 2006 Apr;16(4):305-17. Epub 2005 Nov 29.

PMID:
16319083
11.

Binding free energy calculations of galectin-3-ligand interactions.

Mandal TK, Mukhopadhyay C.

Protein Eng. 2002 Dec;15(12):979-86.

PMID:
12601137
12.

Thermodynamic binding studies of bivalent oligosaccharides to galectin-1, galectin-3, and the carbohydrate recognition domain of galectin-3.

Ahmad N, Gabius HJ, Sabesan S, Oscarson S, Brewer CF.

Glycobiology. 2004 Sep;14(9):817-25. Epub 2004 May 17.

PMID:
15148296
14.

Different affinity of galectins for human serum glycoproteins: galectin-3 binds many protease inhibitors and acute phase proteins.

Cederfur C, Salomonsson E, Nilsson J, Halim A, Oberg CT, Larson G, Nilsson UJ, Leffler H.

Glycobiology. 2008 May;18(5):384-94. doi: 10.1093/glycob/cwn015. Epub 2008 Feb 9.

PMID:
18263896
15.

Assembly, organization and regulation of cell-surface receptors by lectin-glycan complexes.

Elola MT, Blidner AG, Ferragut F, Bracalente C, Rabinovich GA.

Biochem J. 2015 Jul 1;469(1):1-16. doi: 10.1042/BJ20150461. Review.

PMID:
26173257
16.

Fragment-based development of triazole-substituted O-galactosyl aldoximes with fragment-induced affinity and selectivity for galectin-3.

Tejler J, Salameh B, Leffler H, Nilsson UJ.

Org Biomol Chem. 2009 Oct 7;7(19):3982-90. doi: 10.1039/b909091f. Epub 2009 Jul 20.

PMID:
19763301
18.

Negative regulation of RPE cell attachment by carbohydrate-dependent cell surface binding of galectin-3 and inhibition of the ERK-MAPK pathway.

Alge-Priglinger CS, André S, Schoeffl H, Kampik A, Strauss RW, Kernt M, Gabius HJ, Priglinger SG.

Biochimie. 2011 Mar;93(3):477-88. doi: 10.1016/j.biochi.2010.10.021. Epub 2010 Nov 20.

PMID:
21094672
19.

Cancer-associated glycoforms of gelatinase B exhibit a decreased level of binding to galectin-3.

Fry SA, Van den Steen PE, Royle L, Wormald MR, Leathem AJ, Opdenakker G, McDonnell JM, Dwek RA, Rudd PM.

Biochemistry. 2006 Dec 26;45(51):15249-58. Epub 2006 Dec 6.

PMID:
17176047
20.

Human galectin-3 selective and high affinity inhibitors. Present state and future perspectives.

Téllez-Sanz R, García-Fuentes L, Vargas-Berenguel A.

Curr Med Chem. 2013;20(24):2979-90. Review.

PMID:
23834183

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