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Items: 1 to 20 of 311

1.

PARP-mediated repair, homologous recombination, and back-up non-homologous end joining-like repair of single-strand nicks.

Metzger MJ, Stoddard BL, Monnat RJ Jr.

DNA Repair (Amst). 2013 Jul;12(7):529-34. doi: 10.1016/j.dnarep.2013.04.004. Epub 2013 May 16.

2.

A role for human homologous recombination factors in suppressing microhomology-mediated end joining.

Ahrabi S, Sarkar S, Pfister SX, Pirovano G, Higgins GS, Porter AC, Humphrey TC.

Nucleic Acids Res. 2016 Jul 8;44(12):5743-57. doi: 10.1093/nar/gkw326. Epub 2016 Apr 29.

3.

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways.

Wang M, Wu W, Wu W, Rosidi B, Zhang L, Wang H, Iliakis G.

Nucleic Acids Res. 2006;34(21):6170-82. Epub 2006 Nov 6.

4.

Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks.

Vriend LE, Prakash R, Chen CC, Vanoli F, Cavallo F, Zhang Y, Jasin M, Krawczyk PM.

Nucleic Acids Res. 2016 Jun 20;44(11):5204-17. doi: 10.1093/nar/gkw179. Epub 2016 Mar 21.

5.
6.

The underlying mechanism for the PARP and BRCA synthetic lethality: clearing up the misunderstandings.

Helleday T.

Mol Oncol. 2011 Aug;5(4):387-93. doi: 10.1016/j.molonc.2011.07.001. Epub 2011 Jul 22. Review.

7.

Remodeling and spacing factor 1 (RSF1) deposits centromere proteins at DNA double-strand breaks to promote non-homologous end-joining.

Helfricht A, Wiegant WW, Thijssen PE, Vertegaal AC, Luijsterburg MS, van Attikum H.

Cell Cycle. 2013 Sep 15;12(18):3070-82. doi: 10.4161/cc.26033. Epub 2013 Aug 20.

8.

Marked contribution of alternative end-joining to chromosome-translocation-formation by stochastically induced DNA double-strand-breaks in G2-phase human cells.

Soni A, Siemann M, Pantelias GE, Iliakis G.

Mutat Res Genet Toxicol Environ Mutagen. 2015 Nov;793:2-8. doi: 10.1016/j.mrgentox.2015.07.002. Epub 2015 Jul 4.

PMID:
26520366
9.

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.

Beck C, Boehler C, Guirouilh Barbat J, Bonnet ME, Illuzzi G, Ronde P, Gauthier LR, Magroun N, Rajendran A, Lopez BS, Scully R, Boussin FD, Schreiber V, Dantzer F.

Nucleic Acids Res. 2014 May;42(9):5616-32. doi: 10.1093/nar/gku174. Epub 2014 Mar 5.

10.

Requirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.

Soni A, Siemann M, Grabos M, Murmann T, Pantelias GE, Iliakis G.

Nucleic Acids Res. 2014 Jun;42(10):6380-92. doi: 10.1093/nar/gku298. Epub 2014 Apr 19.

11.

Inhibition of homologous recombination by hyperthermia shunts early double strand break repair to non-homologous end-joining.

Bergs JW, Krawczyk PM, Borovski T, ten Cate R, Rodermond HM, Stap J, Medema JP, Haveman J, Essers J, van Bree C, Stalpers LJ, Kanaar R, Aten JA, Franken NA.

DNA Repair (Amst). 2013 Jan 1;12(1):38-45. doi: 10.1016/j.dnarep.2012.10.008. Epub 2012 Dec 11.

PMID:
23237939
12.

Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair.

Davis L, Maizels N.

Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):E924-32. doi: 10.1073/pnas.1400236111. Epub 2014 Feb 20.

13.

Inhibition of DNA damage repair by artificial activation of PARP with siDNA.

Croset A, Cordelières FP, Berthault N, Buhler C, Sun JS, Quanz M, Dutreix M.

Nucleic Acids Res. 2013 Aug;41(15):7344-55. doi: 10.1093/nar/gkt522. Epub 2013 Jun 12.

14.

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

Xu G, Chapman JR, Brandsma I, Yuan J, Mistrik M, Bouwman P, Bartkova J, Gogola E, Warmerdam D, Barazas M, Jaspers JE, Watanabe K, Pieterse M, Kersbergen A, Sol W, Celie PH, Schouten PC, van den Broek B, Salman A, Nieuwland M, de Rink I, de Ronde J, Jalink K, Boulton SJ, Chen J, van Gent DC, Bartek J, Jonkers J, Borst P, Rottenberg S.

Nature. 2015 May 28;521(7553):541-4. doi: 10.1038/nature14328. Epub 2015 Mar 23.

15.

The efficiency of homologous recombination and non-homologous end joining systems in repairing double-strand breaks during cell cycle progression.

Bee L, Fabris S, Cherubini R, Mognato M, Celotti L.

PLoS One. 2013 Jul 11;8(7):e69061. doi: 10.1371/journal.pone.0069061. Print 2013.

16.

Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template.

Metzger MJ, McConnell-Smith A, Stoddard BL, Miller AD.

Nucleic Acids Res. 2011 Feb;39(3):926-35. doi: 10.1093/nar/gkq826. Epub 2010 Sep 28.

17.

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks.

Krietsch J, Caron MC, Gagné JP, Ethier C, Vignard J, Vincent M, Rouleau M, Hendzel MJ, Poirier GG, Masson JY.

Nucleic Acids Res. 2012 Nov 1;40(20):10287-301. doi: 10.1093/nar/gks798. Epub 2012 Aug 31.

18.

Sensitization to radiation and alkylating agents by inhibitors of poly(ADP-ribose) polymerase is enhanced in cells deficient in DNA double-strand break repair.

Löser DA, Shibata A, Shibata AK, Woodbine LJ, Jeggo PA, Chalmers AJ.

Mol Cancer Ther. 2010 Jun;9(6):1775-87. doi: 10.1158/1535-7163.MCT-09-1027. Epub 2010 Jun 8.

19.

IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination.

Chitnis MM, Lodhia KA, Aleksic T, Gao S, Protheroe AS, Macaulay VM.

Oncogene. 2014 Nov 6;33(45):5262-73. doi: 10.1038/onc.2013.460. Epub 2013 Nov 4.

20.

Exploiting the Achilles heel of cancer: the therapeutic potential of poly(ADP-ribose) polymerase inhibitors in BRCA2-defective cancer.

Kyle S, Thomas HD, Mitchell J, Curtin NJ.

Br J Radiol. 2008 Oct;81 Spec No 1:S6-11. doi: 10.1259/bjr/99111297.

PMID:
18820000

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