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Items: 1 to 20 of 753

1.

Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells.

He H, Zang LH, Feng YS, Chen LX, Kang N, Tashiro S, Onodera S, Qiu F, Ikejima T.

J Ethnopharmacol. 2013 Jul 9;148(2):544-55. doi: 10.1016/j.jep.2013.04.051. Epub 2013 May 14.

PMID:
23684722
2.

Nitric oxide induces apoptosis and autophagy; autophagy down-regulates NO synthesis in physalin A-treated A375-S2 human melanoma cells.

He H, Feng YS, Zang LH, Liu WW, Ding LQ, Chen LX, Kang N, Hayashi T, Tashiro S, Onodera S, Qiu F, Ikejima T.

Food Chem Toxicol. 2014 Sep;71:128-35. doi: 10.1016/j.fct.2014.06.007. Epub 2014 Jun 19.

PMID:
24952311
3.

Physalin A induces G2/M phase cell cycle arrest in human non-small cell lung cancer cells: involvement of the p38 MAPK/ROS pathway.

Kang N, Jian JF, Cao SJ, Zhang Q, Mao YW, Huang YY, Peng YF, Qiu F, Gao XM.

Mol Cell Biochem. 2016 Apr;415(1-2):145-55. doi: 10.1007/s11010-016-2686-1. Epub 2016 Mar 21.

PMID:
27000859
4.

Mechanism of autophagy induction and role of autophagy in antagonizing mitomycin C-induced cell apoptosis in silibinin treated human melanoma A375-S2 cells.

Jiang YY, Yang R, Wang HJ, Huang H, Wu D, Tashiro S, Onodera S, Ikejima T.

Eur J Pharmacol. 2011 May 20;659(1):7-14. doi: 10.1016/j.ejphar.2010.12.043. Epub 2011 Jan 22.

PMID:
21262221
5.

Cinobufagin induces autophagy-mediated cell death in human osteosarcoma U2OS cells through the ROS/JNK/p38 signaling pathway.

Ma K, Zhang C, Huang MY, Li WY, Hu GQ.

Oncol Rep. 2016 Jul;36(1):90-8. doi: 10.3892/or.2016.4782. Epub 2016 Apr 28.

6.

Autophagy inhibits reactive oxygen species-mediated apoptosis via activating p38-nuclear factor-kappa B survival pathways in oridonin-treated murine fibrosarcoma L929 cells.

Cheng Y, Qiu F, Ye YC, Guo ZM, Tashiro S, Onodera S, Ikejima T.

FEBS J. 2009 Mar;276(5):1291-306. doi: 10.1111/j.1742-4658.2008.06864.x.

7.

Isoorientin induces apoptosis and autophagy simultaneously by reactive oxygen species (ROS)-related p53, PI3K/Akt, JNK, and p38 signaling pathways in HepG2 cancer cells.

Yuan L, Wei S, Wang J, Liu X.

J Agric Food Chem. 2014 Jun 11;62(23):5390-400. doi: 10.1021/jf500903g. Epub 2014 Jun 3.

PMID:
24841907
8.

NF-kappab facilitates oridonin-induced apoptosis and autophagy in HT1080 cells through a p53-mediated pathway.

Zhang Y, Wu Y, Wu D, Tashiro S, Onodera S, Ikejima T.

Arch Biochem Biophys. 2009 Sep;489(1-2):25-33. doi: 10.1016/j.abb.2009.07.017. Epub 2009 Jul 29.

PMID:
19646415
9.

Physalin F induces cell apoptosis in human renal carcinoma cells by targeting NF-kappaB and generating reactive oxygen species.

Wu SY, Leu YL, Chang YL, Wu TS, Kuo PC, Liao YR, Teng CM, Pan SL.

PLoS One. 2012;7(7):e40727. doi: 10.1371/journal.pone.0040727. Epub 2012 Jul 16.

10.

Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways.

Looi CY, Moharram B, Paydar M, Wong YL, Leong KH, Mohamad K, Arya A, Wong WF, Mustafa MR.

BMC Complement Altern Med. 2013 Jul 10;13:166. doi: 10.1186/1472-6882-13-166.

11.

Physalin A induces apoptotic cell death and protective autophagy in HT1080 human fibrosarcoma cells.

He H, Zang LH, Feng YS, Wang J, Liu WW, Chen LX, Kang N, Tashiro S, Onodera S, Qiu F, Ikejima T.

J Nat Prod. 2013 May 24;76(5):880-8. doi: 10.1021/np400017k. Epub 2013 May 6.

PMID:
23647462
12.

Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS-p38-p53 pathway.

Liu B, Cheng Y, Zhang B, Bian HJ, Bao JK.

Cancer Lett. 2009 Mar 8;275(1):54-60. doi: 10.1016/j.canlet.2008.09.042. Epub 2008 Nov 17.

PMID:
19010591
13.

Silibinin activated ROS-p38-NF-κB positive feedback and induced autophagic death in human fibrosarcoma HT1080 cells.

Duan WJ, Li QS, Xia MY, Tashiro S, Onodera S, Ikejima T.

J Asian Nat Prod Res. 2011 Jan;13(1):27-35. doi: 10.1080/10286020.2010.540757.

PMID:
21253947
14.

Nitric oxide activated by p38 and NF-kappaB facilitates apoptosis and cell cycle arrest under oxidative stress in evodiamine-treated human melanoma A375-S2 cells.

Yang J, Wu LJ, Tashiro S, Onodera S, Ikejima T.

Free Radic Res. 2008 Jan;42(1):1-11. doi: 10.1080/10715760701762407.

PMID:
18324518
15.

Methyl 3-hydroxyimino-11-oxoolean-12-en-28-oate (HIMOXOL), a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MDA-MB-231 breast cancer cells.

Lisiak N, Paszel-Jaworska A, Bednarczyk-Cwynar B, Zaprutko L, Kaczmarek M, Rybczyńska M.

Chem Biol Interact. 2014 Feb 5;208:47-57. doi: 10.1016/j.cbi.2013.11.009. Epub 2013 Nov 27.

PMID:
24291674
16.

Bufalin induces autophagy-mediated cell death in human colon cancer cells through reactive oxygen species generation and JNK activation.

Xie CM, Chan WY, Yu S, Zhao J, Cheng CH.

Free Radic Biol Med. 2011 Oct 1;51(7):1365-75. doi: 10.1016/j.freeradbiomed.2011.06.016. Epub 2011 Jun 29.

PMID:
21763418
17.

Effects of small interfering RNA inhibit Class I phosphoinositide 3-kinase on human gastric cancer cells.

Zhu BS, Yu LY, Zhao K, Wu YY, Cheng XL, Wu Y, Zhong FY, Gong W, Chen Q, Xing CG.

World J Gastroenterol. 2013 Mar 21;19(11):1760-9. doi: 10.3748/wjg.v19.i11.1760.

18.

Triptolide induces cell death in pancreatic cancer cells by apoptotic and autophagic pathways.

Mujumdar N, Mackenzie TN, Dudeja V, Chugh R, Antonoff MB, Borja-Cacho D, Sangwan V, Dawra R, Vickers SM, Saluja AK.

Gastroenterology. 2010 Aug;139(2):598-608. doi: 10.1053/j.gastro.2010.04.046. Epub 2010 Apr 29.

19.

Piperlongumine induces apoptotic and autophagic death of the primary myeloid leukemia cells from patients via activation of ROS-p38/JNK pathways.

Xiong XX, Liu JM, Qiu XY, Pan F, Yu SB, Chen XQ.

Acta Pharmacol Sin. 2015 Mar;36(3):362-74. doi: 10.1038/aps.2014.141. Epub 2015 Jan 26.

20.

Induction of α-phellandrene on autophagy in human liver tumor cells.

Hsieh LC, Hsieh SL, Chen CT, Chung JG, Wang JJ, Wu CC.

Am J Chin Med. 2015;43(1):121-36. doi: 10.1142/S0192415X15500081. Epub 2015 Feb 4.

PMID:
25649747

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