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Items: 1 to 20 of 314

1.

Fibrosis reduces severity of acute-on-chronic pancreatitis in humans.

Acharya C, Cline RA, Jaligama D, Noel P, Delany JP, Bae K, Furlan A, Baty CJ, Karlsson JM, Rosario BL, Patel K, Mishra V, Dugampudi C, Yadav D, Navina S, Singh VP.

Gastroenterology. 2013 Aug;145(2):466-75. doi: 10.1053/j.gastro.2013.05.012. Epub 2013 May 15.

2.

Peripancreatic fat necrosis worsens acute pancreatitis independent of pancreatic necrosis via unsaturated fatty acids increased in human pancreatic necrosis collections.

Noel P, Patel K, Durgampudi C, Trivedi RN, de Oliveira C, Crowell MD, Pannala R, Lee K, Brand R, Chennat J, Slivka A, Papachristou GI, Khalid A, Whitcomb DC, DeLany JP, Cline RA, Acharya C, Jaligama D, Murad FM, Yadav D, Navina S, Singh VP.

Gut. 2016 Jan;65(1):100-11. doi: 10.1136/gutjnl-2014-308043. Epub 2014 Dec 10.

3.

Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity.

Navina S, Acharya C, DeLany JP, Orlichenko LS, Baty CJ, Shiva SS, Durgampudi C, Karlsson JM, Lee K, Bae KT, Furlan A, Behari J, Liu S, McHale T, Nichols L, Papachristou GI, Yadav D, Singh VP.

Sci Transl Med. 2011 Nov 2;3(107):107ra110. doi: 10.1126/scitranslmed.3002573.

4.

Involvement of thrombopoietin in acinar cell necrosis in L-arginine-induced acute pancreatitis in mice.

Shen J, Wan R, Hu G, Wang F, Shen J, Wang X.

Cytokine. 2012 Oct;60(1):294-301. doi: 10.1016/j.cyto.2012.05.005. Epub 2012 Jun 13.

PMID:
22698803
5.

Acinar inflammatory response to lipid derivatives generated in necrotic fat during acute pancreatitis.

Mateu A, Ramudo L, Manso MA, Closa D, De Dios I.

Biochim Biophys Acta. 2014 Sep;1842(9):1879-86. doi: 10.1016/j.bbadis.2014.06.016. Epub 2014 Jun 21.

6.

Role of pancreatic fat in the outcomes of pancreatitis.

Acharya C, Navina S, Singh VP.

Pancreatology. 2014 Sep-Oct;14(5):403-8. doi: 10.1016/j.pan.2014.06.004. Epub 2014 Jul 1. Review.

7.

Lipolysis of visceral adipocyte triglyceride by pancreatic lipases converts mild acute pancreatitis to severe pancreatitis independent of necrosis and inflammation.

Patel K, Trivedi RN, Durgampudi C, Noel P, Cline RA, DeLany JP, Navina S, Singh VP.

Am J Pathol. 2015 Mar;185(3):808-19. doi: 10.1016/j.ajpath.2014.11.019. Epub 2015 Jan 8.

8.

Cerulein-induced chronic pancreatitis does not require intra-acinar activation of trypsinogen in mice.

Sah RP, Dudeja V, Dawra RK, Saluja AK.

Gastroenterology. 2013 May;144(5):1076-1085.e2. doi: 10.1053/j.gastro.2013.01.041. Epub 2013 Jan 24.

9.

Value of adipokines in predicting the severity of acute pancreatitis: comprehensive review.

Karpavicius A, Dambrauskas Z, Sileikis A, Vitkus D, Strupas K.

World J Gastroenterol. 2012 Dec 7;18(45):6620-7. doi: 10.3748/wjg.v18.i45.6620. Review.

10.

Obesity and fat distribution imply a greater systemic inflammatory response and a worse prognosis in acute pancreatitis.

Sempere L, Martinez J, de Madaria E, Lozano B, Sanchez-Paya J, Jover R, Perez-Mateo M.

Pancreatology. 2008;8(3):257-64. doi: 10.1159/000134273. Epub 2008 May 22.

PMID:
18497538
11.

Effects of disease severity and necrosis on pancreatic dysfunction after acute pancreatitis.

Garip G, Sarandöl E, Kaya E.

World J Gastroenterol. 2013 Nov 28;19(44):8065-70. doi: 10.3748/wjg.v19.i44.8065.

12.

Reduced pancreatic volume and beta-cell area in patients with chronic pancreatitis.

Schrader H, Menge BA, Schneider S, Belyaev O, Tannapfel A, Uhl W, Schmidt WE, Meier JJ.

Gastroenterology. 2009 Feb;136(2):513-22. doi: 10.1053/j.gastro.2008.10.083. Epub 2008 Nov 6.

PMID:
19041312
13.

Interleukin-18, together with interleukin-12, induces severe acute pancreatitis in obese but not in nonobese leptin-deficient mice.

Sennello JA, Fayad R, Pini M, Gove ME, Ponemone V, Cabay RJ, Siegmund B, Dinarello CA, Fantuzzi G.

Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):8085-90. doi: 10.1073/pnas.0804091105. Epub 2008 May 30.

14.

Impact of chronic and acute high-fat feeding on acute experimental pancreatitis complicated by endotoxinaemia.

Segersvärd R, Sylván M, Lempinen M, Larsson J, Permert J.

Scand J Gastroenterol. 2004 Jan;39(1):74-80.

PMID:
14992565
15.

A murine model of obesity implicates the adipokine milieu in the pathogenesis of severe acute pancreatitis.

Zyromski NJ, Mathur A, Pitt HA, Lu D, Gripe JT, Walker JJ, Yancey K, Wade TE, Swartz-Basile DA.

Am J Physiol Gastrointest Liver Physiol. 2008 Sep;295(3):G552-8. doi: 10.1152/ajpgi.90278.2008. Epub 2008 Jun 26.

PMID:
18583460
16.

Acute lipotoxicity regulates severity of biliary acute pancreatitis without affecting its initiation.

Durgampudi C, Noel P, Patel K, Cline R, Trivedi RN, DeLany JP, Yadav D, Papachristou GI, Lee K, Acharya C, Jaligama D, Navina S, Murad F, Singh VP.

Am J Pathol. 2014 Jun;184(6):1773-84. doi: 10.1016/j.ajpath.2014.02.015.

17.

Inhibition of Ras signalling reduces neutrophil infiltration and tissue damage in severe acute pancreatitis.

Yu C, Merza M, Luo L, Thorlacius H.

Eur J Pharmacol. 2015 Jan 5;746:245-51. doi: 10.1016/j.ejphar.2014.11.020. Epub 2014 Nov 25.

PMID:
25460024
18.

A population-based study of severity in patients with acute on chronic pancreatitis.

Akshintala VS, Hutfless SM, Yadav D, Khashab MA, Lennon AM, Makary MA, Hirose K, Andersen DK, Kalloo AN, Singh VK.

Pancreas. 2013 Nov;42(8):1245-50. doi: 10.1097/MPA.0b013e3182a85af3.

PMID:
24152950
19.

Effect of diet-induced obesity on acute pancreatitis induced by administration of interleukin-12 plus interleukin-18 in mice.

Pini M, Sennello JA, Cabay RJ, Fantuzzi G.

Obesity (Silver Spring). 2010 Mar;18(3):476-81. doi: 10.1038/oby.2009.263. Epub 2009 Aug 20.

20.

Influence of Fatty Liver on the Severity and Clinical Outcome in Acute Pancreatitis.

Xu C, Qiao Z, Lu Y, Zhang D, Jia Z, Zhuang X, Shi Y, Xu T, Xing L, Shen J.

PLoS One. 2015 Nov 16;10(11):e0142278. doi: 10.1371/journal.pone.0142278. eCollection 2015.

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