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Items: 1 to 20 of 145

1.

[p15(INK4B) methylation on prognosis and response to decitabine in patients with MDS].

Zhang Y, Song LX, Wu LY, Chang CK, Li X.

Zhonghua Xue Ye Xue Za Zhi. 2013 Mar;34(3):237-41. doi: 10.3760/cma.j.issn.0253-2727.2013.03.013. Chinese.

PMID:
23683424
2.

Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-Aza-2'-deoxycytidine (decitabine) treatment.

Daskalakis M, Nguyen TT, Nguyen C, Guldberg P, Köhler G, Wijermans P, Jones PA, Lübbert M.

Blood. 2002 Oct 15;100(8):2957-64.

3.

Hypermethylation of the p15(INK4B) gene in acute leukemia and myelodysplastic syndromes.

Chen H, Wu S.

Chin Med J (Engl). 2002 Jul;115(7):987-90.

PMID:
12150726
4.
5.

Methylation of the p15(INK4b) gene in myelodysplastic syndromes is frequent and acquired during disease progression.

Quesnel B, Guillerm G, Vereecque R, Wattel E, Preudhomme C, Bauters F, Vanrumbeke M, Fenaux P.

Blood. 1998 Apr 15;91(8):2985-90.

6.

Clinical outcome of treatment with a combined regimen of decitabine and aclacinomycin/cytarabine for patients with refractory acute myeloid leukemia.

Song LX, Xu L, Li X, Chang CK, Zhang Y, Wu LY, He Q, Zhang QX, Li X.

Ann Hematol. 2012 Dec;91(12):1879-86. doi: 10.1007/s00277-012-1550-y. Epub 2012 Aug 16.

PMID:
22895556
7.

Downregulation of HO-1 promoted apoptosis induced by decitabine via increasing p15INK4B promoter demethylation in myelodysplastic syndrome.

Ma D, Fang Q, Wang P, Gao R, Sun J, Li Y, Hu XY, Wang JS.

Gene Ther. 2015 Apr;22(4):287-96. doi: 10.1038/gt.2015.1. Epub 2015 Feb 5.

PMID:
25652099
8.

Negative effect of DNA hypermethylation on the outcome of intensive chemotherapy in older patients with high-risk myelodysplastic syndromes and acute myeloid leukemia following myelodysplastic syndrome.

Grövdal M, Khan R, Aggerholm A, Antunovic P, Astermark J, Bernell P, Engström LM, Kjeldsen L, Linder O, Nilsson L, Olsson A, Wallvik J, Tangen JM, Oberg G, Jacobsen SE, Hokland P, Porwit A, Hellström-Lindberg E.

Clin Cancer Res. 2007 Dec 1;13(23):7107-12.

9.

[Methylation of P15INK4B gene in patients with myelodysplastic syndromes and demethylating effects of drugs].

Ye XS, Liu T, Cui X, Meng WT, Xi YM.

Sichuan Da Xue Xue Bao Yi Xue Ban. 2007 Jan;38(1):57-9. Chinese.

PMID:
17294728
10.

Update of the decitabine experience in higher risk myelodysplastic syndrome and analysis of prognostic factors associated with outcome.

Kantarjian HM, O'Brien S, Shan J, Aribi A, Garcia-Manero G, Jabbour E, Ravandi F, Cortes J, Davisson J, Issa JP.

Cancer. 2007 Jan 15;109(2):265-73.

11.

Epigenetic alterations of p15(INK4B) and p16(INK4A) genes in pediatric primary myelodysplastic syndrome.

Rodrigues EF, Santos-Rebouças CB, Gonçalves Pimentel MM, Mencalha AL, Dobbin J, Da Costa ES, Fernandez Cde S, Bouzas LF, Abdelhay E, De Souza Fernandez T.

Leuk Lymphoma. 2010 Oct;51(10):1887-94. doi: 10.3109/10428194.2010.505820.

PMID:
20658957
12.

In vivo effects of decitabine in myelodysplasia and acute myeloid leukemia: review of cytogenetic and molecular studies.

Hackanson B, Robbel C, Wijermans P, Lübbert M.

Ann Hematol. 2005 Dec;84 Suppl 1:32-8. Review.

PMID:
16292549
13.

Comparative analysis of hypermethylation of cell cycle control and DNA-mismatch repair genes in low-density and CD34+ bone marrow cells from patients with myelodysplastic syndrome.

Hofmann WK, Takeuchi S, Takeuchi N, Thiel E, Hoelzer D, Koeffler HP.

Leuk Res. 2006 Nov;30(11):1347-53. Epub 2006 May 8.

PMID:
16682076
14.

[Detection of methylation levels of multi-genes by real-time PCR in patients with myelodysplastic syndrome].

Wang YC, DU X, Geng SX, Li YY, Weng JY, Lu ZS, Zhong LY, Deng CX, Lai PL, Huang X.

Zhonghua Xue Ye Xue Za Zhi. 2011 Apr;32(4):254-8. Chinese.

PMID:
21569709
15.

CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine.

Raj K, John A, Ho A, Chronis C, Khan S, Samuel J, Pomplun S, Thomas NS, Mufti GJ.

Leukemia. 2007 Sep;21(9):1937-44. Epub 2007 Jul 5.

PMID:
17611569
16.

Role of heme oxygenase-1 in demethylating effects on SKM-1 cells induced by decitabine.

Gao R, Ma D, Wang P, Sun J, Wang JS, Fang Q.

Genet Mol Res. 2015 Dec 22;14(4):17788-98. doi: 10.4238/2015.December.22.3.

17.

Influence of methylated p15 and p16 genes on clinicopathological features in colorectal cancer.

Ishiguro A, Takahata T, Saito M, Yoshiya G, Tamura Y, Sasaki M, Munakata A.

J Gastroenterol Hepatol. 2006 Aug;21(8):1334-9.

PMID:
16872319
18.

[Abnormality of p15(INK4b) gene and myelodysplastic syndrome].

Wang Z, Li YQ.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2002 Aug;10(4):362-5. Review. Chinese.

PMID:
12513775
19.

The lower risk MDS patient at risk of rapid progression.

Mittelman M, Oster HS, Hoffman M, Neumann D.

Leuk Res. 2010 Dec;34(12):1551-5. doi: 10.1016/j.leukres.2010.05.023. Epub 2010 Jun 22. Review.

PMID:
20573398
20.

Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome.

Iwai M, Kiyoi H, Ozeki K, Kinoshita T, Emi N, Ohno R, Naoe T.

Leukemia. 2005 Aug;19(8):1367-75.

PMID:
15902282

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