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Items: 1 to 20 of 104

1.

Protein engineering of oxidosqualene-lanosterol cyclase into triterpene monocyclase.

Chang CH, Wen HY, Shie WS, Lu CT, Li ME, Liu YT, Li WH, Wu TK.

Org Biomol Chem. 2013 Jul 7;11(25):4214-9. doi: 10.1039/c3ob40493e.

PMID:
23680980
2.

The cysteine 703 to isoleucine or histidine mutation of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae generates an iridal-type triterpenoid.

Chang CH, Chen YC, Tseng SW, Liu YT, Wen HY, Li WH, Huang CY, Ko CY, Wang TT, Wu TK.

Biochimie. 2012 Nov;94(11):2376-81. doi: 10.1016/j.biochi.2012.06.014. Epub 2012 Jun 23.

PMID:
22732192
4.
6.

Protein engineering of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase into parkeol synthase.

Liu YT, Hu TC, Chang CH, Shie WS, Wu TK.

Org Lett. 2012 Oct 19;14(20):5222-5. doi: 10.1021/ol302341h. Epub 2012 Oct 8.

PMID:
23043506
8.
10.

Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases.

Ito R, Mori K, Hashimoto I, Nakano C, Sato T, Hoshino T.

Org Lett. 2011 May 20;13(10):2678-81. doi: 10.1021/ol200777d. Epub 2011 Apr 28.

PMID:
21526825
11.

Importance of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase tyrosine 707 residue for chair-boat bicyclic ring formation and deprotonation reactions.

Wu TK, Wang TT, Chang CH, Liu YT, Shie WS.

Org Lett. 2008 Nov 6;10(21):4959-62. doi: 10.1021/ol802036c. Epub 2008 Oct 9.

PMID:
18842050
13.
14.
15.

Catalytic mechanism and product specificity of oxidosqualene-lanosterol cyclase: a QM/MM study.

Tian BX, Eriksson LA.

J Phys Chem B. 2012 Nov 29;116(47):13857-62. doi: 10.1021/jp3091396. Epub 2012 Nov 16.

PMID:
23130825
16.
17.

Mutation of isoleucine 705 of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae affects lanosterol's C/D-ring cyclization and 17α/β-exocyclic side chain stereochemistry.

Wu TK, Chang YC, Liu YT, Chang CH, Wen HY, Li WH, Shie WS.

Org Biomol Chem. 2011 Feb 21;9(4):1092-7. doi: 10.1039/c0ob00582g. Epub 2010 Dec 15.

PMID:
21157613
18.

Engineering triterpene production in Saccharomyces cerevisiae-beta-amyrin synthase from Artemisia annua.

Kirby J, Romanini DW, Paradise EM, Keasling JD.

FEBS J. 2008 Apr;275(8):1852-9. doi: 10.1111/j.1742-4658.2008.06343.x. Epub 2008 Mar 8.

19.
20.

Steric bulk at cycloartenol synthase position 481 influences cyclization and deprotonation.

Matsuda SP, Darr LB, Hart EA, Herrera JB, McCann KE, Meyer MM, Pang J, Schepmann HG.

Org Lett. 2000 Jul 27;2(15):2261-3.

PMID:
10930258

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