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Items: 1 to 20 of 136

1.

Age-related bone deterioration is diminished by disrupted collagen sensing in integrin α2β1 deficient mice.

Stange R, Kronenberg D, Timmen M, Everding J, Hidding H, Eckes B, Hansen U, Holtkamp M, Karst U, Pap T, Raschke MJ.

Bone. 2013 Sep;56(1):48-54. doi: 10.1016/j.bone.2013.05.003. Epub 2013 May 13.

PMID:
23680479
2.

Interactions of primary fibroblasts and keratinocytes with extracellular matrix proteins: contribution of alpha2beta1 integrin.

Zhang ZG, Bothe I, Hirche F, Zweers M, Gullberg D, Pfitzer G, Krieg T, Eckes B, Aumailley M.

J Cell Sci. 2006 May 1;119(Pt 9):1886-95.

4.

Collagen integrin receptors regulate early osteoblast differentiation induced by BMP-2.

Jikko A, Harris SE, Chen D, Mendrick DL, Damsky CH.

J Bone Miner Res. 1999 Jul;14(7):1075-83.

5.

Biofunctionalization of a generic collagenous triple helix with the α2β1 integrin binding site allows molecular force measurements.

Niland S, Westerhausen C, Schneider SW, Eckes B, Schneider MF, Eble JA.

Int J Biochem Cell Biol. 2011 May;43(5):721-31. doi: 10.1016/j.biocel.2011.01.013. Epub 2011 Jan 22.

PMID:
21262375
6.

Novel α2β1 integrin inhibitors reveal that integrin binding to collagen under shear stress conditions does not require receptor preactivation.

Nissinen L, Koivunen J, Käpylä J, Salmela M, Nieminen J, Jokinen J, Sipilä K, Pihlavisto M, Pentikäinen OT, Marjamäki A, Heino J.

J Biol Chem. 2012 Dec 28;287(53):44694-702. doi: 10.1074/jbc.M111.309450. Epub 2012 Nov 6.

7.

Role of the alpha2-integrin in osteoblast-specific gene expression and activation of the Osf2 transcription factor.

Xiao G, Wang D, Benson MD, Karsenty G, Franceschi RT.

J Biol Chem. 1998 Dec 4;273(49):32988-94.

8.
9.

Alpha2beta1 integrin and development of atherosclerosis in a mouse model: assessment of risk.

Grenache DG, Coleman T, Semenkovich CF, Santoro SA, Zutter MM.

Arterioscler Thromb Vasc Biol. 2003 Nov 1;23(11):2104-9. Epub 2003 Sep 25.

10.

The G60S connexin 43 mutation activates the osteoblast lineage and results in a resorption-stimulating bone matrix and abrogation of old-age-related bone loss.

Zappitelli T, Chen F, Moreno L, Zirngibl RA, Grynpas M, Henderson JE, Aubin JE.

J Bone Miner Res. 2013 Nov;28(11):2400-13. doi: 10.1002/jbmr.1965.

11.

Wound healing in the alpha2beta1 integrin-deficient mouse: altered keratinocyte biology and dysregulated matrix metalloproteinase expression.

Grenache DG, Zhang Z, Wells LE, Santoro SA, Davidson JM, Zutter MM.

J Invest Dermatol. 2007 Feb;127(2):455-66. Epub 2006 Oct 26.

12.
13.

The loss of α2β1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis.

Peters MA, Wendholt D, Strietholt S, Frank S, Pundt N, Korb-Pap A, Joosten LA, van den Berg WB, Kollias G, Eckes B, Pap T.

Arthritis Rheum. 2012 May;64(5):1359-68. doi: 10.1002/art.33487.

14.

Two synergistic activation mechanisms of alpha2beta1 integrin-mediated collagen binding.

Connors WL, Jokinen J, White DJ, Puranen JS, Kankaanpää P, Upla P, Tulla M, Johnson MS, Heino J.

J Biol Chem. 2007 May 11;282(19):14675-83. Epub 2007 Mar 19.

15.

Expression of collagen-binding integrin receptors in the mammalian sclera and their regulation during the development of myopia.

McBrien NA, Metlapally R, Jobling AI, Gentle A.

Invest Ophthalmol Vis Sci. 2006 Nov;47(11):4674-82.

PMID:
17065473
16.

Vascular smooth muscle cells orchestrate the assembly of type I collagen via alpha2beta1 integrin, RhoA, and fibronectin polymerization.

Li S, Van Den Diepstraten C, D'Souza SJ, Chan BM, Pickering JG.

Am J Pathol. 2003 Sep;163(3):1045-56.

17.

Osteoclast deficiency results in disorganized matrix, reduced mineralization, and abnormal osteoblast behavior in developing bone.

Dai XM, Zong XH, Akhter MP, Stanley ER.

J Bone Miner Res. 2004 Sep;19(9):1441-51. Epub 2004 Jun 2.

18.

The beneficial effect of icaritin on osteoporotic bone is dependent on the treatment initiation timing in adult ovariectomized rats.

Peng S, Zhang G, Zhang BT, Guo B, He Y, Bakker AJ, Pan X, Zhen W, Hung L, Qin L, Leung WN.

Bone. 2013 Jul;55(1):230-40. doi: 10.1016/j.bone.2013.02.012. Epub 2013 Feb 26.

PMID:
23486180
19.

Syndecan-1 supports integrin alpha2beta1-mediated adhesion to collagen.

Vuoriluoto K, Jokinen J, Kallio K, Salmivirta M, Heino J, Ivaska J.

Exp Cell Res. 2008 Nov 1;314(18):3369-81. doi: 10.1016/j.yexcr.2008.07.005. Epub 2008 Jul 15.

PMID:
18657535
20.

Integrins α2β1 and α11β1 regulate the survival of mesenchymal stem cells on collagen I.

Popov C, Radic T, Haasters F, Prall WC, Aszodi A, Gullberg D, Schieker M, Docheva D.

Cell Death Dis. 2011 Jul 28;2:e186. doi: 10.1038/cddis.2011.71.

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