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Items: 1 to 20 of 98

1.

IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG).

Zirkel A, Lederer M, Stöhr N, Pazaitis N, Hüttelmaier S.

Nucleic Acids Res. 2013 Jul;41(13):6618-36. doi: 10.1093/nar/gkt410. Epub 2013 May 15.

2.

The transcription factor LEF-1 induces an epithelial-mesenchymal transition in MDCK cells independent of β-catenin.

Kobayashi W, Ozawa M.

Biochem Biophys Res Commun. 2013 Dec 6;442(1-2):133-8. doi: 10.1016/j.bbrc.2013.11.031. Epub 2013 Nov 19.

PMID:
24269234
3.

IGF2BP1: a post-transcriptional "driver" of tumor cell migration.

Stöhr N, Hüttelmaier S.

Cell Adh Migr. 2012 Jul-Aug;6(4):312-8. doi: 10.4161/cam.20628. Epub 2012 Jul 1.

4.

Metadherin enhances the invasiveness of breast cancer cells by inducing epithelial to mesenchymal transition.

Li X, Kong X, Huo Q, Guo H, Yan S, Yuan C, Moran MS, Shao C, Yang Q.

Cancer Sci. 2011 Jun;102(6):1151-7. doi: 10.1111/j.1349-7006.2011.01919.x. Epub 2011 Apr 5.

5.

E-cadherin controls beta-catenin and NF-kappaB transcriptional activity in mesenchymal gene expression.

Solanas G, Porta-de-la-Riva M, Agustí C, Casagolda D, Sánchez-Aguilera F, Larriba MJ, Pons F, Peiró S, Escrivà M, Muñoz A, Duñach M, de Herreros AG, Baulida J.

J Cell Sci. 2008 Jul 1;121(Pt 13):2224-34. doi: 10.1242/jcs.021667.

6.

Smoking induces epithelial-to-mesenchymal transition in non-small cell lung cancer through HDAC-mediated downregulation of E-cadherin.

Nagathihalli NS, Massion PP, Gonzalez AL, Lu P, Datta PK.

Mol Cancer Ther. 2012 Nov;11(11):2362-72. doi: 10.1158/1535-7163.MCT-12-0107. Epub 2012 Aug 29.

7.

Hepatocyte growth factor activates Wnt pathway by transcriptional activation of LEF1 to facilitate tumor invasion.

Huang FI, Chen YL, Chang CN, Yuan RH, Jeng YM.

Carcinogenesis. 2012 Jun;33(6):1142-8. doi: 10.1093/carcin/bgs131. Epub 2012 Mar 20.

PMID:
22436613
8.

Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription.

Christova T, Mojtahedi G, Hamel PA.

Int J Biochem Cell Biol. 2010 May;42(5):630-40. doi: 10.1016/j.biocel.2009.12.006. Epub 2009 Dec 16.

PMID:
20006729
9.

EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer.

Haslehurst AM, Koti M, Dharsee M, Nuin P, Evans K, Geraci J, Childs T, Chen J, Li J, Weberpals J, Davey S, Squire J, Park PC, Feilotter H.

BMC Cancer. 2012 Mar 19;12:91. doi: 10.1186/1471-2407-12-91.

10.

HMGA2 induces transcription factor Slug expression to promote epithelial-to-mesenchymal transition and contributes to colon cancer progression.

Li Y, Zhao Z, Xu C, Zhou Z, Zhu Z, You T.

Cancer Lett. 2014 Dec 1;355(1):130-40. doi: 10.1016/j.canlet.2014.09.007. Epub 2014 Sep 11.

PMID:
25218351
11.

TGF-β1-induced EMT of non-transformed prostate hyperplasia cells is characterized by early induction of SNAI2/Slug.

Slabáková E, Pernicová Z, Slavíčková E, Staršíchová A, Kozubík A, Souček K.

Prostate. 2011 Sep;71(12):1332-43. doi: 10.1002/pros.21350. Epub 2011 Feb 14.

PMID:
21321977
12.

Snail regulated by PKC/GSK-3β pathway is crucial for EGF-induced epithelial-mesenchymal transition (EMT) of cancer cells.

Liu ZC, Chen XH, Song HX, Wang HS, Zhang G, Wang H, Chen DY, Fang R, Liu H, Cai SH, Du J.

Cell Tissue Res. 2014 Nov;358(2):491-502. doi: 10.1007/s00441-014-1953-2. Epub 2014 Aug 16.

PMID:
25124796
13.

Snail and Slug collaborate on EMT and tumor metastasis through miR-101-mediated EZH2 axis in oral tongue squamous cell carcinoma.

Zheng M, Jiang YP, Chen W, Li KD, Liu X, Gao SY, Feng H, Wang SS, Jiang J, Ma XR, Cen X, Tang YJ, Chen Y, Lin YF, Tang YL, Liang XH.

Oncotarget. 2015 Mar 30;6(9):6797-810.

14.

A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial-mesenchymal transition.

Kim NH, Kim HS, Li XY, Lee I, Choi HS, Kang SE, Cha SY, Ryu JK, Yoon D, Fearon ER, Rowe RG, Lee S, Maher CA, Weiss SJ, Yook JI.

J Cell Biol. 2011 Oct 31;195(3):417-33. doi: 10.1083/jcb.201103097. Epub 2011 Oct 24.

15.

Interferon consensus sequence-binding protein (ICSBP) promotes epithelial-to-mesenchymal transition (EMT)-like phenomena, cell-motility, and invasion via TGF-β signaling in U2OS cells.

Sung JY, Park SY, Kim JH, Kang HG, Yoon JH, Na YS, Kim YN, Park BK.

Cell Death Dis. 2014 May 15;5:e1224. doi: 10.1038/cddis.2014.189.

16.

Fucoidan induces changes in the epithelial to mesenchymal transition and decreases metastasis by enhancing ubiquitin-dependent TGFβ receptor degradation in breast cancer.

Hsu HY, Lin TY, Hwang PA, Tseng LM, Chen RH, Tsao SM, Hsu J.

Carcinogenesis. 2013 Apr;34(4):874-84. doi: 10.1093/carcin/bgs396. Epub 2012 Dec 28.

PMID:
23275155
17.

IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling.

Stöhr N, Köhn M, Lederer M, Glass M, Reinke C, Singer RH, Hüttelmaier S.

Genes Dev. 2012 Jan 15;26(2):176-89. doi: 10.1101/gad.177642.111.

18.

Matrix metalloproteinase-9 cooperates with transcription factor Snail to induce epithelial-mesenchymal transition.

Lin CY, Tsai PH, Kandaswami CC, Lee PP, Huang CJ, Hwang JJ, Lee MT.

Cancer Sci. 2011 Apr;102(4):815-27. doi: 10.1111/j.1349-7006.2011.01861.x. Epub 2011 Feb 9.

19.

FoxM1 overexpression promotes epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma.

Meng FD, Wei JC, Qu K, Wang ZX, Wu QF, Tai MH, Liu HC, Zhang RY, Liu C.

World J Gastroenterol. 2015 Jan 7;21(1):196-213. doi: 10.3748/wjg.v21.i1.196.

20.

BMP4 promotes EMT and mesodermal commitment in human embryonic stem cells via SLUG and MSX2.

Richter A, Valdimarsdottir L, Hrafnkelsdottir HE, Runarsson JF, Omarsdottir AR, Ward-van Oostwaard D, Mummery C, Valdimarsdottir G.

Stem Cells. 2014 Mar;32(3):636-48. doi: 10.1002/stem.1592.

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