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Items: 1 to 20 of 137

1.

Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice.

Suzukawa M, Miller M, Rosenthal P, Cho JY, Doherty TA, Varki A, Broide D.

J Immunol. 2013 Jun 15;190(12):5939-48. doi: 10.4049/jimmunol.1203455.

2.

Mice deficient in the St3gal3 gene product α2,3 sialyltransferase (ST3Gal-III) exhibit enhanced allergic eosinophilic airway inflammation.

Kiwamoto T, Brummet ME, Wu F, Motari MG, Smith DF, Schnaar RL, Zhu Z, Bochner BS.

J Allergy Clin Immunol. 2014 Jan;133(1):240-7.e1-3. doi: 10.1016/j.jaci.2013.05.018.

3.

Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13.

Cho JY, Song DJ, Pham A, Rosenthal P, Miller M, Dayan S, Doherty TA, Varki A, Broide DH.

Respir Res. 2010 Nov 1;11:154. doi: 10.1186/1465-9921-11-154.

4.

Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis.

Kiwamoto T, Katoh T, Evans CM, Janssen WJ, Brummet ME, Hudson SA, Zhu Z, Tiemeyer M, Bochner BS.

J Allergy Clin Immunol. 2015 May;135(5):1329-40.e1-9. doi: 10.1016/j.jaci.2014.10.027.

5.

Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling.

Song DJ, Cho JY, Lee SY, Miller M, Rosenthal P, Soroosh P, Croft M, Zhang M, Varki A, Broide DH.

J Immunol. 2009 Oct 15;183(8):5333-41. doi: 10.4049/jimmunol.0801421.

6.

Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils.

Zhang M, Angata T, Cho JY, Miller M, Broide DH, Varki A.

Blood. 2007 May 15;109(10):4280-7.

7.

Siglec-F-dependent negative regulation of allergen-induced eosinophilia depends critically on the experimental model.

McMillan SJ, Richards HE, Crocker PR.

Immunol Lett. 2014 Jul;160(1):11-6. doi: 10.1016/j.imlet.2014.03.008.

8.

Siglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis.

Rubinstein E, Cho JY, Rosenthal P, Chao J, Miller M, Pham A, Aceves SS, Varki A, Broide DH.

J Pediatr Gastroenterol Nutr. 2011 Oct;53(4):409-16. doi: 10.1097/MPG.0b013e3182182ff8.

9.

Characterization of expression of glycan ligands for Siglec-F in normal mouse lungs.

Guo JP, Brummet ME, Myers AC, Na HJ, Rowland E, Schnaar RL, Zheng T, Zhu Z, Bochner BS.

Am J Respir Cell Mol Biol. 2011 Feb;44(2):238-43. doi: 10.1165/rcmb.2010-0007OC.

10.

Anti-Siglec-F antibody inhibits oral egg allergen induced intestinal eosinophilic inflammation in a mouse model.

Song DJ, Cho JY, Miller M, Strangman W, Zhang M, Varki A, Broide DH.

Clin Immunol. 2009 Apr;131(1):157-69. doi: 10.1016/j.clim.2008.11.009.

11.

Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue.

Patnode ML, Cheng CW, Chou CC, Singer MS, Elin MS, Uchimura K, Crocker PR, Khoo KH, Rosen SD.

J Biol Chem. 2013 Sep 13;288(37):26533-45. doi: 10.1074/jbc.M113.485409.

12.

Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils.

Zimmermann N, McBride ML, Yamada Y, Hudson SA, Jones C, Cromie KD, Crocker PR, Rothenberg ME, Bochner BS.

Allergy. 2008 Sep;63(9):1156-63. doi: 10.1111/j.1398-9995.2008.01709.x.

13.

The role of lung epithelial ligands for Siglec-8 and Siglec-F in eosinophilic inflammation.

Kiwamoto T, Katoh T, Tiemeyer M, Bochner BS.

Curr Opin Allergy Clin Immunol. 2013 Feb;13(1):106-11. doi: 10.1097/ACI.0b013e32835b594a. Review.

14.

Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors.

Bochner BS.

Clin Exp Allergy. 2009 Mar;39(3):317-24. doi: 10.1111/j.1365-2222.2008.03173.x. Review.

15.

Selective suppression of Th2 cell-mediated lung eosinophilic inflammation by anti-major facilitator super family domain containing 10 monoclonal antibody.

Nishimura T, Saeki M, Motoi Y, Kitamura N, Mori A, Kaminuma O, Hiroi T.

Allergol Int. 2014 May;63 Suppl 1:29-35. doi: 10.2332/allergolint.13-OA-0635.

16.

Altered eosinophil profile in mice with ST6Gal-1 deficiency: an additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation.

Nasirikenari M, Chandrasekaran EV, Matta KL, Segal BH, Bogner PN, Lugade AA, Thanavala Y, Lee JJ, Lau JT.

J Leukoc Biol. 2010 Mar;87(3):457-66. doi: 10.1189/jlb.1108704.

17.

Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygen.

Mao H, Kano G, Hudson SA, Brummet M, Zimmermann N, Zhu Z, Bochner BS.

PLoS One. 2013 Jun 28;8(6):e68143. doi: 10.1371/journal.pone.0068143.

18.

Antiallergic effect of anti-Siglec-F through reduction of eosinophilic inflammation in murine allergic rhinitis.

Kim YH, Park CS, Lim DH, Son BK, Kim JH, Ahn SH, Bochner BS, Na K, Jang TY.

Am J Rhinol Allergy. 2013 May-Jun;27(3):187-91. doi: 10.2500/ajra.2013.27.3866.

PMID:
23710953
19.

Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma.

Suzukawa M, Morita H, Nambu A, Arae K, Shimura E, Shibui A, Yamaguchi S, Suzukawa K, Nakanishi W, Oboki K, Kajiwara N, Ohno T, Ishii A, Körner H, Cua DJ, Suto H, Yoshimoto T, Iwakura Y, Yamasoba T, Ohta K, Sudo K, Saito H, Okumura K, Broide DH, Matsumoto K, Nakae S.

J Immunol. 2012 Oct 1;189(7):3641-52.

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