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[α-Enolase (ENO1) inhibits epithelial-mesenchymal transition in the A549 cell line
by suppressing ERK1/2 phosphorylation].

Zhou X, Zhang Y, Han N, Guo S, Xiao T, Cheng S, Gao Y, Zhang K.

Zhongguo Fei Ai Za Zhi. 2013 May;16(5):221-6. doi: 10.3779/j.issn.1009-3419.2013.05.01. Chinese.


Alpha-enolase promotes cell glycolysis, growth, migration, and invasion in non-small cell lung cancer through FAK-mediated PI3K/AKT pathway.

Fu QF, Liu Y, Fan Y, Hua SN, Qu HY, Dong SW, Li RL, Zhao MY, Zhen Y, Yu XL, Chen YY, Luo RC, Li R, Li LB, Deng XJ, Fang WY, Liu Z, Song X.

J Hematol Oncol. 2015 Mar 8;8:22. doi: 10.1186/s13045-015-0117-5.


EGCG inhibits transforming growth factor-β-mediated epithelial-to-mesenchymal transition via the inhibition of Smad2 and Erk1/2 signaling pathways in nonsmall cell lung cancer cells.

Liu LC, Tsao TC, Hsu SR, Wang HC, Tsai TC, Kao JY, Way TD.

J Agric Food Chem. 2012 Oct 3;60(39):9863-73. doi: 10.1021/jf303690x. Epub 2012 Sep 19.


ERK1/2 blockade prevents epithelial-mesenchymal transition in lung cancer cells and promotes their sensitivity to EGFR inhibition.

Buonato JM, Lazzara MJ.

Cancer Res. 2014 Jan 1;74(1):309-19. doi: 10.1158/0008-5472.CAN-12-4721. Epub 2013 Oct 9.


Saponins from the roots of Platycodon grandiflorum suppresses TGFβ1-induced epithelial-mesenchymal transition via repression of PI3K/Akt, ERK1/2 and Smad2/3 pathway in human lung carcinoma A549 cells.

Choi JH, Hwang YP, Kim HG, Khanal T, Do MT, Jin SW, Han HJ, Lee HS, Lee YC, Chung YC, Jeong TC, Jeong HG.

Nutr Cancer. 2014;66(1):140-51. doi: 10.1080/01635581.2014.853087. Epub 2013 Dec 16.


Alpha-enolase as a potential cancer prognostic marker promotes cell growth, migration, and invasion in glioma.

Song Y, Luo Q, Long H, Hu Z, Que T, Zhang X, Li Z, Wang G, Yi L, Liu Z, Fang W, Qi S.

Mol Cancer. 2014 Mar 21;13:65. doi: 10.1186/1476-4598-13-65. Erratum in: Mol Cancer. 2015;13:235.


Induction of integrin β3 by sustained ERK activity promotes the invasiveness of TGFβ-induced mesenchymal tumor cells.

Hong SK, Park JR, Kwon OS, Kim KT, Bae GY, Cha HJ.

Cancer Lett. 2016 Jul 1;376(2):339-46. doi: 10.1016/j.canlet.2016.04.012. Epub 2016 Apr 13.


Blocking M2 muscarinic receptor signaling inhibits tumor growth and reverses epithelial-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC).

Zhao Q, Gu X, Zhang C, Lu Q, Chen H, Xu L.

Cancer Biol Ther. 2015;16(4):634-43. doi: 10.1080/15384047.2015.1029835. Epub 2015 Mar 16.


Rubus idaeus L. reverses epithelial-to-mesenchymal transition and suppresses cell invasion and protease activities by targeting ERK1/2 and FAK pathways in human lung cancer cells.

Hsieh YS, Chu SC, Hsu LS, Chen KS, Lai MT, Yeh CH, Chen PN.

Food Chem Toxicol. 2013 Dec;62:908-18. doi: 10.1016/j.fct.2013.10.021. Epub 2013 Oct 24.


Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent.

Davis FM, Azimi I, Faville RA, Peters AA, Jalink K, Putney JW Jr, Goodhill GJ, Thompson EW, Roberts-Thomson SJ, Monteith GR.

Oncogene. 2014 May 1;33(18):2307-16. doi: 10.1038/onc.2013.187. Epub 2013 May 20.


Ski prevents TGF-β-induced EMT and cell invasion by repressing SMAD-dependent signaling in non-small cell lung cancer.

Yang H, Zhan L, Yang T, Wang L, Li C, Zhao J, Lei Z, Li X, Zhang HT.

Oncol Rep. 2015 Jul;34(1):87-94. doi: 10.3892/or.2015.3961. Epub 2015 May 7.


Stereospecific effects of ginsenoside 20-Rg3 inhibits TGF-β1-induced epithelial-mesenchymal transition and suppresses lung cancer migration, invasion and anoikis resistance.

Kim YJ, Choi WI, Jeon BN, Choi KC, Kim K, Kim TJ, Ham J, Jang HJ, Kang KS, Ko H.

Toxicology. 2014 Aug 1;322:23-33. doi: 10.1016/j.tox.2014.04.002. Epub 2014 May 2.


Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis.

Wang H, Zhang H, Tang L, Chen H, Wu C, Zhao M, Yang Y, Chen X, Liu G.

Toxicology. 2013 Jan 7;303:139-46. doi: 10.1016/j.tox.2012.09.017. Epub 2012 Nov 9.


Alisertib induces cell cycle arrest and autophagy and suppresses epithelial-to-mesenchymal transition involving PI3K/Akt/mTOR and sirtuin 1-mediated signaling pathways in human pancreatic cancer cells.

Wang F, Li H, Yan XG, Zhou ZW, Yi ZG, He ZX, Pan ST, Yang YX, Wang ZZ, Zhang X, Yang T, Qiu JX, Zhou SF.

Drug Des Devel Ther. 2015 Jan 17;9:575-601. doi: 10.2147/DDDT.S75221. eCollection 2015.


Up-regulation of sonic hedgehog contributes to TGF-β1-induced epithelial to mesenchymal transition in NSCLC cells.

Maitah MY, Ali S, Ahmad A, Gadgeel S, Sarkar FH.

PLoS One. 2011 Jan 13;6(1):e16068. doi: 10.1371/journal.pone.0016068.


MicroRNA-200c inhibits the metastasis of non-small cell lung cancer cells by targeting ZEB2, an epithelial-mesenchymal transition regulator.

Jiao A, Sui M, Zhang L, Sun P, Geng D, Zhang W, Wang X, Li J.

Mol Med Rep. 2016 Apr;13(4):3349-55. doi: 10.3892/mmr.2016.4901. Epub 2016 Feb 17.


The complex interplay between ERK1/2, TGFβ/Smad, and Jagged/Notch signaling pathways in the regulation of epithelial-mesenchymal transition in retinal pigment epithelium cells.

Chen X, Xiao W, Wang W, Luo L, Ye S, Liu Y.

PLoS One. 2014 May 2;9(5):e96365. doi: 10.1371/journal.pone.0096365. eCollection 2014.


The impact of metformin and salinomycin on transforming growth factor β-induced epithelial-to-mesenchymal transition in non-small cell lung cancer cell lines.

Koeck S, Amann A, Huber JM, Gamerith G, Hilbe W, Zwierzina H.

Oncol Lett. 2016 Apr;11(4):2946-2952. Epub 2016 Mar 9.


MAWBP and MAWD inhibit proliferation and invasion in gastric cancer.

Li DM, Zhang J, Li WM, Cui JT, Pan YM, Liu SQ, Xing R, Lu YY.

World J Gastroenterol. 2013 May 14;19(18):2781-92. doi: 10.3748/wjg.v19.i18.2781.

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