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Items: 1 to 20 of 109

1.

[Effect of berberine, liensinine and neferine on HERG channel expression].

Wei T, Liang Z, Jin Y, Zhang L.

Zhongguo Zhong Yao Za Zhi. 2013 Jan;38(2):239-44. Chinese.

PMID:
23672049
2.

Comparative effects of liensinine and neferine on the human ether-a-go-go-related gene potassium channel and pharmacological activity analysis.

Dong ZX, Zhao X, Gu DF, Shi YQ, Zhang J, Hu XX, Hu MQ, Yang BF, Li BX.

Cell Physiol Biochem. 2012;29(3-4):431-42. doi: 10.1159/000338497. Epub 2012 Apr 3.

3.

Blockade of HERG K+ channel by isoquinoline alkaloid neferine in the stable transfected HEK293 cells.

Gu DF, Li XL, Qi ZP, Shi SS, Hu MQ, Liu DM, She CB, Lv YJ, Li BX, Yang BF.

Naunyn Schmiedebergs Arch Pharmacol. 2009 Aug;380(2):143-51. doi: 10.1007/s00210-009-0419-7. Epub 2009 May 8.

PMID:
19424681
4.

Berberine induces hERG channel deficiency through trafficking inhibition.

Zhang K, Zhi D, Huang T, Gong Y, Yan M, Liu C, Wei T, Dong Z, Li B, Yang B.

Cell Physiol Biochem. 2014;34(3):691-702. doi: 10.1159/000363034. Epub 2014 Aug 18.

5.

[Effects of matrine, oxymatrine and resveratrol on HERG channel expression].

Zhang Y, Du J, Zhang Y, Sun HL, Pan ZW, Lu YJ, Li BX, Yang BF.

Yao Xue Xue Bao. 2007 Feb;42(2):139-44. Chinese.

PMID:
17518040
6.

Mechanism and pharmacological rescue of berberine-induced hERG channel deficiency.

Yan M, Zhang K, Shi Y, Feng L, Lv L, Li B.

Drug Des Devel Ther. 2015 Oct 22;9:5737-47. doi: 10.2147/DDDT.S91561. eCollection 2015.

7.

Human ether-a-go-go-related gene channel blockers and its structural analysis for drug design.

Narayana Moorthy NS, Ramos MJ, Fernandes PA.

Curr Drug Targets. 2013 Jan 1;14(1):102-13. Review.

PMID:
23061466
9.

Structure-activity relationships of pentamidine-affected ion channel trafficking and dofetilide mediated rescue.

Varkevisser R, Houtman MJ, Linder T, de Git KC, Beekman HD, Tidwell RR, Ijzerman AP, Stary-Weinzinger A, Vos MA, van der Heyden MA.

Br J Pharmacol. 2013 Jul;169(6):1322-34. doi: 10.1111/bph.12208.

10.

Inhibitory effects of berberine on IK1, IK, and HERG channels of cardiac myocytes.

Li BX, Yang BF, Zhou J, Xu CQ, Li YR.

Acta Pharmacol Sin. 2001 Feb;22(2):125-31.

11.

Progesterone impairs human ether-a-go-go-related gene (HERG) trafficking by disruption of intracellular cholesterol homeostasis.

Wu ZY, Yu DJ, Soong TW, Dawe GS, Bian JS.

J Biol Chem. 2011 Jun 24;286(25):22186-94. doi: 10.1074/jbc.M110.198853. Epub 2011 Apr 27.

12.

Down-regulation of ether-a-go-go-related gene potassium channel protein through sustained stimulation of AT1 receptor by angiotensin II.

Cai Y, Wang Y, Xu J, Zuo X, Xu Y.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):852-7. doi: 10.1016/j.bbrc.2014.09.014. Epub 2014 Sep 10.

PMID:
25218469
13.

Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells.

Yu D, Lv L, Fang L, Zhang B, Wang J, Zhan G, Zhao L, Zhao X, Li B.

PLoS One. 2017 Aug 1;12(8):e0181823. doi: 10.1371/journal.pone.0181823. eCollection 2017.

14.

Inhibitory effects of a bisbenzylisoquinline alkaloid dauricine on HERG potassium channels.

Zhao J, Lian Y, Lu C, Jing L, Yuan H, Peng S.

J Ethnopharmacol. 2012 Jun 1;141(2):685-91. doi: 10.1016/j.jep.2011.08.054. Epub 2011 Sep 5.

PMID:
21920426
15.

The serum- and glucocorticoid-inducible kinases SGK1 and SGK3 regulate hERG channel expression via ubiquitin ligase Nedd4-2 and GTPase Rab11.

Lamothe SM, Zhang S.

J Biol Chem. 2013 May 24;288(21):15075-84. doi: 10.1074/jbc.M113.453670. Epub 2013 Apr 15.

16.
17.

The enhancement of cardiac toxicity by concomitant administration of Berberine and macrolides.

Zhi D, Feng PF, Sun JL, Guo F, Zhang R, Zhao X, Li BX.

Eur J Pharm Sci. 2015 Aug 30;76:149-55. doi: 10.1016/j.ejps.2015.05.009. Epub 2015 May 11.

PMID:
25976224
18.

A novel missense mutation causing a G487R substitution in the S2-S3 loop of human ether-à-go-go-related gene channel.

Kinoshita K, Yamaguchi Y, Nishide K, Kimoto K, Nonobe Y, Fujita A, Asano K, Tabata T, Mori H, Inoue H, Hata Y, Fukurotani K, Nishida N.

J Cardiovasc Electrophysiol. 2012 Nov;23(11):1246-53. doi: 10.1111/j.1540-8167.2012.02383.x. Epub 2012 Jul 5.

PMID:
22764740
19.

HIV Tat protein inhibits hERG K+ channels: a potential mechanism of HIV infection induced LQTs.

Bai YL, Liu HB, Sun B, Zhang Y, Li Q, Hu CW, Zhu JX, Gong DM, Teng X, Zhang Q, Yang BF, Dong DL.

J Mol Cell Cardiol. 2011 Nov;51(5):876-80. doi: 10.1016/j.yjmcc.2011.07.017. Epub 2011 Jul 28.

PMID:
21820442
20.

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