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Items: 1 to 20 of 207

1.

IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice.

Thaker AI, Rao MS, Bishnupuri KS, Kerr TA, Foster L, Marinshaw JM, Newberry RD, Stenson WF, Ciorba MA.

Gastroenterology. 2013 Aug;145(2):416-25.e1-4. doi: 10.1053/j.gastro.2013.05.002. Epub 2013 May 10.

2.

MicroRNA 301A Promotes Intestinal Inflammation and Colitis-Associated Cancer Development by Inhibiting BTG1.

He C, Yu T, Shi Y, Ma C, Yang W, Fang L, Sun M, Wu W, Xiao F, Guo F, Chen M, Yang H, Qian J, Cong Y, Liu Z.

Gastroenterology. 2017 May;152(6):1434-1448.e15. doi: 10.1053/j.gastro.2017.01.049. Epub 2017 Feb 11.

PMID:
28193514
3.

EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients.

Srivatsa S, Paul MC, Cardone C, Holcmann M, Amberg N, Pathria P, Diamanti MA, Linder M, Timelthaler G, Dienes HP, Kenner L, Wrba F, Prager GW, Rose-John S, Eferl R, Liguori G, Botti G, Martinelli E, Greten FR, Ciardiello F, Sibilia M.

Gastroenterology. 2017 Jul;153(1):178-190.e10. doi: 10.1053/j.gastro.2017.03.053. Epub 2017 Apr 9.

4.

Human Colon Tumors Express a Dominant-Negative Form of SIGIRR That Promotes Inflammation and Colitis-Associated Colon Cancer in Mice.

Zhao J, Bulek K, Gulen MF, Zepp JA, Karagkounis G, Martin BN, Zhou H, Yu M, Liu X, Huang E, Fox PL, Kalady MF, Markowitz SD, Li X.

Gastroenterology. 2015 Dec;149(7):1860-1871.e8. doi: 10.1053/j.gastro.2015.08.051. Epub 2015 Sep 5.

5.

Inhibition of indoleamine 2,3-dioxygenase 1 expression alters immune response in colon tumor microenvironment in mice.

Takamatsu M, Hirata A, Ohtaki H, Hoshi M, Ando T, Ito H, Hatano Y, Tomita H, Kuno T, Saito K, Seishima M, Hara A.

Cancer Sci. 2015 Aug;106(8):1008-15. doi: 10.1111/cas.12705. Epub 2015 Jul 14.

6.

Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor-κB, and Up-regulating Expression of MicroRNA-21.

Yang Y, Weng W, Peng J, Hong L, Yang L, Toiyama Y, Gao R, Liu M, Yin M, Pan C, Li H, Guo B, Zhu Q, Wei Q, Moyer MP, Wang P, Cai S, Goel A, Qin H, Ma Y.

Gastroenterology. 2017 Mar;152(4):851-866.e24. doi: 10.1053/j.gastro.2016.11.018. Epub 2016 Nov 19.

7.

1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells.

Liu X, Zhou W, Zhang X, Ding Y, Du Q, Hu R.

Int J Cancer. 2018 Apr 1. doi: 10.1002/ijc.31417. [Epub ahead of print]

PMID:
29607498
8.

Severity of DSS-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88-NF-kB transcriptional networks.

Shon WJ, Lee YK, Shin JH, Choi EY, Shin DM.

Sci Rep. 2015 Nov 27;5:17305. doi: 10.1038/srep17305.

9.

Pyrin Inflammasome Regulates Tight Junction Integrity to Restrict Colitis and Tumorigenesis.

Sharma D, Malik A, Guy CS, Karki R, Vogel P, Kanneganti TD.

Gastroenterology. 2018 Mar;154(4):948-964.e8. doi: 10.1053/j.gastro.2017.11.276. Epub 2017 Dec 2.

PMID:
29203393
10.

Role of milk fat globule-epidermal growth factor 8 in colonic inflammation and carcinogenesis.

Kusunoki R, Ishihara S, Tada Y, Oka A, Sonoyama H, Fukuba N, Oshima N, Moriyama I, Yuki T, Kawashima K, Ansary MM, Tajima Y, Maruyama R, Nabika T, Kinoshita Y.

J Gastroenterol. 2015 Aug;50(8):862-75. doi: 10.1007/s00535-014-1036-x. Epub 2015 Jan 18.

PMID:
25596854
11.

Interferon-γ induces a tryptophan-selective amino acid transporter in human colonic epithelial cells and mouse dendritic cells.

Bhutia YD, Babu E, Ganapathy V.

Biochim Biophys Acta. 2015 Feb;1848(2):453-62. doi: 10.1016/j.bbamem.2014.10.021. Epub 2014 Oct 23.

12.

Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer.

Kang JH, Jang JE, Mishra SK, Lee HJ, Nho CW, Shin D, Jin M, Kim MK, Choi C, Oh SH.

J Ethnopharmacol. 2015 Sep 15;173:303-12. doi: 10.1016/j.jep.2015.07.030. Epub 2015 Jul 22.

PMID:
26210065
13.

Indoleamine 2,3 dioxygenase in intestinal disease.

Ciorba MA.

Curr Opin Gastroenterol. 2013 Mar;29(2):146-52. doi: 10.1097/MOG.0b013e32835c9cb3. Review.

14.

MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18.

Salcedo R, Worschech A, Cardone M, Jones Y, Gyulai Z, Dai RM, Wang E, Ma W, Haines D, O'hUigin C, Marincola FM, Trinchieri G.

J Exp Med. 2010 Aug 2;207(8):1625-36. doi: 10.1084/jem.20100199. Epub 2010 Jul 12.

15.

BMI1 and MEL18 Promote Colitis-Associated Cancer in Mice via REG3B and STAT3.

Liu X, Wei W, Li X, Shen P, Ju D, Wang Z, Zhang R, Yang F, Chen C, Cao K, Zhu G, Chen H, Chen L, Sui J, Zhang E, Wu K, Wang F, Zhao L, Xi R.

Gastroenterology. 2017 Dec;153(6):1607-1620. doi: 10.1053/j.gastro.2017.07.044. Epub 2017 Aug 3.

PMID:
28780076
16.

Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice.

Jackman KA, Brait VH, Wang Y, Maghzal GJ, Ball HJ, McKenzie G, De Silva TM, Stocker R, Sobey CG.

Naunyn Schmiedebergs Arch Pharmacol. 2011 May;383(5):471-81. doi: 10.1007/s00210-011-0611-4. Epub 2011 Feb 27.

PMID:
21359968
17.

Smad2/3 linker phosphorylation is a possible marker of cancer stem cells and correlates with carcinogenesis in a mouse model of colitis-associated colorectal cancer.

Suzuki R, Fukui T, Kishimoto M, Miyamoto S, Takahashi Y, Takeo M, Mitsuyama T, Sakaguchi Y, Uchida K, Nishio A, Okazaki K.

J Crohns Colitis. 2015 Jul;9(7):565-74. doi: 10.1093/ecco-jcc/jjv073. Epub 2015 Apr 23.

PMID:
25908723
18.

Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice.

Kim HB, Kim M, Park YS, Park I, Kim T, Yang SY, Cho CJ, Hwang D, Jung JH, Markowitz SD, Hwang SW, Yang SK, Lim DS, Myung SJ.

Gastroenterology. 2017 Feb;152(3):616-630. doi: 10.1053/j.gastro.2016.11.005. Epub 2016 Nov 15.

19.

The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells.

Opitz CA, Litzenburger UM, Opitz U, Sahm F, Ochs K, Lutz C, Wick W, Platten M.

PLoS One. 2011;6(5):e19823. doi: 10.1371/journal.pone.0019823. Epub 2011 May 20.

20.

MicroRNA214 Is Associated With Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-Associated Cancer in Mice.

Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, Tsichlis PN, Pothoulakis C, Verspaget HW, Iliopoulos D.

Gastroenterology. 2015 Oct;149(4):981-92.e11. doi: 10.1053/j.gastro.2015.05.057. Epub 2015 Jun 6.

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