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Items: 1 to 20 of 96

1.

Rapamycin upregulates autophagy by inhibiting the mTOR-ULK1 pathway, resulting in reduced podocyte injury.

Wu L, Feng Z, Cui S, Hou K, Tang L, Zhou J, Cai G, Xie Y, Hong Q, Fu B, Chen X.

PLoS One. 2013 May 8;8(5):e63799. doi: 10.1371/journal.pone.0063799.

2.

Trehalose, an mTOR independent autophagy inducer, alleviates human podocyte injury after puromycin aminonucleoside treatment.

Kang YL, Saleem MA, Chan KW, Yung BY, Law HK.

PLoS One. 2014 Nov 20;9(11):e113520. doi: 10.1371/journal.pone.0113520.

3.

Na+/H+ exchanger-1 reduces podocyte injury caused by endoplasmic reticulum stress via autophagy activation.

Feng Z, Tang L, Wu L, Cui S, Hong Q, Cai G, Wu D, Fu B, Wei R, Chen X.

Lab Invest. 2014 Apr;94(4):439-54. doi: 10.1038/labinvest.2014.4.

4.

The cytoprotective role of autophagy in puromycin aminonucleoside treated human podocytes.

Kang YL, Saleem MA, Chan KW, Yung BY, Law HK.

Biochem Biophys Res Commun. 2014 Jan 10;443(2):628-34. doi: 10.1016/j.bbrc.2013.12.015.

5.

Rapamycin and interleukin-1β impair brain-derived neurotrophic factor-dependent neuron survival by modulating autophagy.

Smith ED, Prieto GA, Tong L, Sears-Kraxberger I, Rice JD, Steward O, Cotman CW.

J Biol Chem. 2014 Jul 25;289(30):20615-29.

6.

mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes.

Vollenbröker B, George B, Wolfgart M, Saleem MA, Pavenstädt H, Weide T.

Am J Physiol Renal Physiol. 2009 Feb;296(2):F418-26. doi: 10.1152/ajprenal.90319.2008.

7.

(Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose.

Li C, Siragy HM.

Am J Physiol Endocrinol Metab. 2015 Aug 1;309(3):E302-10. doi: 10.1152/ajpendo.00603.2014.

8.

Rapamycin promotes podocyte autophagy and ameliorates renal injury in diabetic mice.

Xiao T, Guan X, Nie L, Wang S, Sun L, He T, Huang Y, Zhang J, Yang K, Wang J, Zhao J.

Mol Cell Biochem. 2014 Sep;394(1-2):145-54. doi: 10.1007/s11010-014-2090-7.

PMID:
24850187
9.

Coordinate autophagy and mTOR pathway inhibition enhances cell death in melanoma.

Xie X, White EP, Mehnert JM.

PLoS One. 2013;8(1):e55096. doi: 10.1371/journal.pone.0055096.

10.

GIV/girdin links vascular endothelial growth factor signaling to Akt survival signaling in podocytes independent of nephrin.

Wang H, Misaki T, Taupin V, Eguchi A, Ghosh P, Farquhar MG.

J Am Soc Nephrol. 2015 Feb;26(2):314-27. doi: 10.1681/ASN.2013090985.

11.

Inhibition of MTOR disrupts autophagic flux in podocytes.

Cinà DP, Onay T, Paltoo A, Li C, Maezawa Y, De Arteaga J, Jurisicova A, Quaggin SE.

J Am Soc Nephrol. 2012 Mar;23(3):412-20. doi: 10.1681/ASN.2011070690.

12.

Mammalian target of rapamycin signaling in the podocyte.

Inoki K, Huber TB.

Curr Opin Nephrol Hypertens. 2012 May;21(3):251-7. doi: 10.1097/MNH.0b013e3283520f38. Review.

PMID:
22388550
13.

Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury.

Eid AA, Ford BM, Bhandary B, de Cassia Cavaglieri R, Block K, Barnes JL, Gorin Y, Choudhury GG, Abboud HE.

Diabetes. 2013 Aug;62(8):2935-47. doi: 10.2337/db12-1504.

14.

Autophagy inhibition induces podocyte apoptosis by activating the pro-apoptotic pathway of endoplasmic reticulum stress.

Fang L, Li X, Luo Y, He W, Dai C, Yang J.

Exp Cell Res. 2014 Apr 1;322(2):290-301. doi: 10.1016/j.yexcr.2014.01.001.

PMID:
24424244
15.

Rho-kinase inhibition prevents proteinuria in immune-complex-mediated antipodocyte nephritis.

Meyer-Schwesinger C, Dehde S, Sachs M, Mathey S, Arefi K, Gatzemeier S, Balabanov S, Becker JU, Thaiss F, Meyer TN.

Am J Physiol Renal Physiol. 2012 Oct;303(7):F1015-25. doi: 10.1152/ajprenal.00380.2011.

16.

Suppression of autophagy is protective in high glucose-induced cardiomyocyte injury.

Kobayashi S, Xu X, Chen K, Liang Q.

Autophagy. 2012 Apr;8(4):577-92. doi: 10.4161/auto.18980.

17.

Dysregulated autophagy contributes to podocyte damage in Fabry's disease.

Liebau MC, Braun F, Höpker K, Weitbrecht C, Bartels V, Müller RU, Brodesser S, Saleem MA, Benzing T, Schermer B, Cybulla M, Kurschat CE.

PLoS One. 2013 May 17;8(5):e63506. doi: 10.1371/journal.pone.0063506.

18.

Autophagy protects podocytes from sublytic complement induced injury.

Lv Q, Yang F, Chen K, Zhang Y.

Exp Cell Res. 2016 Feb 15;341(2):132-8. doi: 10.1016/j.yexcr.2016.02.009.

PMID:
26883468
19.

Autophagy can repair endoplasmic reticulum stress damage of the passive Heymann nephritis model as revealed by proteomics analysis.

Wang L, Hong Q, Lv Y, Feng Z, Zhang X, Wu L, Cui S, Hou K, Su H, Huang Z, Wu D, Chen X.

J Proteomics. 2012 Jul 16;75(13):3866-76. doi: 10.1016/j.jprot.2012.04.016.

PMID:
22595305
20.

NF-κB upregulates ubiquitin C-terminal hydrolase 1 in diseased podocytes in glomerulonephritis.

Zhang H, Mao X, Sun Y, Hu R, Luo W, Zhao Z, Chen Q, Zhang Z.

Mol Med Rep. 2015 Aug;12(2):2893-901. doi: 10.3892/mmr.2015.3780.

PMID:
25976522
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