Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 66

1.

Identification of 5-Iodotubercidin as a genotoxic drug with anti-cancer potential.

Zhang X, Jia D, Liu H, Zhu N, Zhang W, Feng J, Yin J, Hao B, Cui D, Deng Y, Xie D, He L, Li B.

PLoS One. 2013 May 7;8(5):e62527. doi: 10.1371/journal.pone.0062527.

2.

Sterigmatocystin-induced DNA damage triggers G2 arrest via an ATM/p53-related pathway in human gastric epithelium GES-1 cells in vitro.

Zhang D, Cui Y, Shen H, Xing L, Cui J, Wang J, Zhang X.

PLoS One. 2013 May 21;8(5):e65044. doi: 10.1371/journal.pone.0065044.

3.

The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

Thomas A, Perry T, Berhane S, Oldreive C, Zlatanou A, Williams LR, Weston VJ, Stankovic T, Kearns P, Pors K, Grand RJ, Stewart GS.

Oncogene. 2015 Jun;34(25):3336-48. doi: 10.1038/onc.2014.266.

PMID:
25132271
4.

Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells.

Shin DY, Sung Kang H, Kim GY, Kim WJ, Yoo YH, Choi YH.

Biomed Pharmacother. 2013 May;67(4):305-11. doi: 10.1016/j.biopha.2013.01.004.

PMID:
23582784
5.

The Topoisomerase 1 Inhibitor Austrobailignan-1 Isolated from Koelreuteria henryi Induces a G2/M-Phase Arrest and Cell Death Independently of p53 in Non-Small Cell Lung Cancer Cells.

Wu CC, Huang KF, Yang TY, Li YL, Wen CL, Hsu SL, Chen TH.

PLoS One. 2015 Jul 6;10(7):e0132052. doi: 10.1371/journal.pone.0132052.

6.

D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation.

Juang SH, Lung CC, Hsu PC, Hsu KS, Li YC, Hong PC, Shiah HS, Kuo CC, Huang CW, Wang YC, Huang L, Chen TS, Chen SF, Fu KC, Hsu CL, Lin MJ, Chang CJ, Ashendel CL, Chan TC, Chou KM, Chang JY.

Mol Cancer Ther. 2007 Jan;6(1):193-202.

7.

Starvation-induced activation of ATM/Chk2/p53 signaling sensitizes cancer cells to cisplatin.

Shi Y, Felley-Bosco E, Marti TM, Orlowski K, Pruschy M, Stahel RA.

BMC Cancer. 2012 Dec 4;12:571. doi: 10.1186/1471-2407-12-571.

8.

E2F1-dependent pathways are involved in amonafide analogue 7-d-induced DNA damage, G2/M arrest, and apoptosis in p53-deficient K562 cells.

Li Y, Shao J, Shen K, Xu Y, Liu J, Qian X.

J Cell Biochem. 2012 Oct;113(10):3165-77. doi: 10.1002/jcb.24194.

PMID:
22593008
9.
10.

Irofulven induces replication-dependent CHK2 activation related to p53 status.

Wang Y, Wiltshire T, Senft J, Reed E, Wang W.

Biochem Pharmacol. 2007 Feb 15;73(4):469-80.

11.

The histone deacetylase inhibitor trichostatin A induces cell cycle arrest and apoptosis in colorectal cancer cells via p53-dependent and -independent pathways.

Meng J, Zhang HH, Zhou CX, Li C, Zhang F, Mei QB.

Oncol Rep. 2012 Jul;28(1):384-8. doi: 10.3892/or.2012.1793.

PMID:
22552631
12.

ATM-p53 pathway causes G2/M arrest, but represses apoptosis in pseudolaric acid B-treated HeLa cells.

Yao G, Qi M, Ji X, Fan S, Xu L, Hayashi T, Tashiro S, Onodera S, Ikejima T.

Arch Biochem Biophys. 2014 Sep 15;558:51-60. doi: 10.1016/j.abb.2014.05.029.

PMID:
24929187
13.
14.

Ribosomal S6 Kinase 2 (RSK2) maintains genomic stability by activating the Atm/p53-dependent DNA damage pathway.

Lim HC, Xie L, Zhang W, Li R, Chen ZC, Wu GZ, Cui SS, Tan EK, Zeng L.

PLoS One. 2013 Sep 23;8(9):e74334. doi: 10.1371/journal.pone.0074334.

15.

Berberine, a genotoxic alkaloid, induces ATM-Chk1 mediated G2 arrest in prostate cancer cells.

Wang Y, Liu Q, Liu Z, Li B, Sun Z, Zhou H, Zhang X, Gong Y, Shao C.

Mutat Res. 2012 Jun 1;734(1-2):20-9. doi: 10.1016/j.mrfmmm.2012.04.005.

PMID:
22561209
16.

Cell death by the quinoxaline dioxide DCQ in human colon cancer cells is enhanced under hypoxia and is independent of p53 and p21.

El-Khatib M, Geara F, Haddadin MJ, Gali-Muhtasib H.

Radiat Oncol. 2010 Nov 15;5:107. doi: 10.1186/1748-717X-5-107.

17.

Widdrol activates DNA damage checkpoint through the signaling Chk2-p53-Cdc25A-p21-MCM4 pathway in HT29 cells.

Yun HJ, Hyun SK, Park JH, Kim BW, Kwon HJ.

Mol Cell Biochem. 2012 Apr;363(1-2):281-9. doi: 10.1007/s11010-011-1180-z.

PMID:
22160829
18.

Sodium salicylate acts through direct inhibition of phosphoinositide 3-kinase-like kinases to modulate topoisomerase-mediated DNA damage responses.

Fan JR, Huang TH, Wen CY, Shen TL, Li TK.

Eur J Pharmacol. 2010 Jul 25;638(1-3):13-20. doi: 10.1016/j.ejphar.2010.04.012.

PMID:
20406630
19.

[Cell cycle regulation after exposure to ionizing radiation].

Teyssier F, Bay JO, Dionet C, Verrelle P.

Bull Cancer. 1999 Apr;86(4):345-57. Review. French.

20.

Oxaliplatin-induced gamma-H2AX activation via both p53-dependent and -independent pathways but is not associated with cell cycle arrest in human colorectal cancer cells.

Chiu SJ, Lee YJ, Hsu TS, Chen WS.

Chem Biol Interact. 2009 Dec 10;182(2-3):173-82. doi: 10.1016/j.cbi.2009.08.019.

PMID:
19735649
Items per page

Supplemental Content

Support Center