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Items: 1 to 20 of 118

1.

Human ALKBH7 is required for alkylation and oxidation-induced programmed necrosis.

Fu D, Jordan JJ, Samson LD.

Genes Dev. 2013 May 15;27(10):1089-100. doi: 10.1101/gad.215533.113. Epub 2013 May 10.

2.

The atomic resolution structure of human AlkB homolog 7 (ALKBH7), a key protein for programmed necrosis and fat metabolism.

Wang G, He Q, Feng C, Liu Y, Deng Z, Qi X, Wu W, Mei P, Chen Z.

J Biol Chem. 2014 Oct 3;289(40):27924-36. doi: 10.1074/jbc.M114.590505. Epub 2014 Aug 13.

3.
4.

Alkylating DNA damage stimulates a regulated form of necrotic cell death.

Zong WX, Ditsworth D, Bauer DE, Wang ZQ, Thompson CB.

Genes Dev. 2004 Jun 1;18(11):1272-82. Epub 2004 May 14.

5.

Poly ADP-ribose polymerase (PARP) inhibitors transiently protect leukemia cells from alkylating agent induced cell death by three different effects.

Pogrebniak A, Schemainda I, Pelka-Fleischer R, Nüssler V, Hasmann M.

Eur J Med Res. 2003 Oct 22;8(10):438-50.

PMID:
14594650
6.

ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage.

Jordan JJ, Chhim S, Margulies CM, Allocca M, Bronson RT, Klungland A, Samson LD, Fu D.

Cell Death Dis. 2017 Jul 20;8(7):e2947. doi: 10.1038/cddis.2017.343.

7.

Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

Moubarak RS, Yuste VJ, Artus C, Bouharrour A, Greer PA, Menissier-de Murcia J, Susin SA.

Mol Cell Biol. 2007 Jul;27(13):4844-62. Epub 2007 Apr 30.

8.

Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction.

Cipriani G, Rapizzi E, Vannacci A, Rizzuto R, Moroni F, Chiarugi A.

J Biol Chem. 2005 Apr 29;280(17):17227-34. Epub 2005 Mar 4.

9.

Benzo[a]pyrene-induced necrosis in the HepG(2) cells via PARP-1 activation and NAD(+) depletion.

Lin T, Yang MS.

Toxicology. 2008 Mar 12;245(1-2):147-53. doi: 10.1016/j.tox.2007.12.020. Epub 2007 Dec 31.

PMID:
18243466
10.
11.

Vitamin A depletion causes oxidative stress, mitochondrial dysfunction, and PARP-1-dependent energy deprivation.

Chiu HJ, Fischman DA, Hammerling U.

FASEB J. 2008 Nov;22(11):3878-87. doi: 10.1096/fj.08-112375. Epub 2008 Aug 1.

12.

Inhibition of poly(ADP-ribose) polymerase (PARP) influences the mode of sulfur mustard (SM)-induced cell death in HaCaT cells.

Kehe K, Raithel K, Kreppel H, Jochum M, Worek F, Thiermann H.

Arch Toxicol. 2008 Jul;82(7):461-70. Epub 2007 Nov 29.

PMID:
18046540
13.

Neuronal trauma model: in search of Thanatos.

Cole K, Perez-Polo JR.

Int J Dev Neurosci. 2004 Nov;22(7):485-96. Review.

PMID:
15465278
14.

Mitochondrial impairment induced by poly(ADP-ribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation.

Tanaka S, Takehashi M, Iida S, Kitajima T, Kamanaka Y, Stedeford T, Banasik M, Ueda K.

J Neurochem. 2005 Oct;95(1):179-90.

15.

Poly(ADP-ribose) polymerase-1 protects neurons against apoptosis induced by oxidative stress.

Diaz-Hernandez JI, Moncada S, Bolaños JP, Almeida A.

Cell Death Differ. 2007 Jun;14(6):1211-21. Epub 2007 Mar 9.

16.

PARP-1 inhibition prevents oxidative and nitrosative stress-induced endothelial cell death via transactivation of the VEGF receptor 2.

Mathews MT, Berk BC.

Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):711-7. doi: 10.1161/ATVBAHA.107.156406. Epub 2008 Jan 31.

17.
18.

PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent.

Ethier C, Tardif M, Arul L, Poirier GG.

PLoS One. 2012;7(10):e47978. doi: 10.1371/journal.pone.0047978. Epub 2012 Oct 24.

19.

Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress.

Du L, Zhang X, Han YY, Burke NA, Kochanek PM, Watkins SC, Graham SH, Carcillo JA, Szabó C, Clark RS.

J Biol Chem. 2003 May 16;278(20):18426-33. Epub 2003 Mar 7.

20.

Molecular mechanisms underlying selective cytotoxic activity of BZL101, an extract of Scutellaria barbata, towards breast cancer cells.

Fong S, Shoemaker M, Cadaoas J, Lo A, Liao W, Tagliaferri M, Cohen I, Shtivelman E.

Cancer Biol Ther. 2008 Apr;7(4):577-86. Epub 2008 Jan 7.

PMID:
18305410

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