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Items: 1 to 20 of 166

1.

Merlin, the NF2 gene product.

Pećina-Šlaus N.

Pathol Oncol Res. 2013 Jul;19(3):365-73. doi: 10.1007/s12253-013-9644-y. Epub 2013 May 12. Review.

PMID:
23666797
2.

NF2: the wizardry of merlin.

Xiao GH, Chernoff J, Testa JR.

Genes Chromosomes Cancer. 2003 Dec;38(4):389-99. Review.

PMID:
14566860
3.

NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth.

James MF, Han S, Polizzano C, Plotkin SR, Manning BD, Stemmer-Rachamimov AO, Gusella JF, Ramesh V.

Mol Cell Biol. 2009 Aug;29(15):4250-61. doi: 10.1128/MCB.01581-08. Epub 2009 May 18.

4.

Transduction of wild-type merlin into human schwannoma cells decreases schwannoma cell growth and induces apoptosis.

Schulze KM, Hanemann CO, Müller HW, Hanenberg H.

Hum Mol Genet. 2002 Jan 1;11(1):69-76.

PMID:
11773000
6.
7.

Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells.

Lallemand D, Saint-Amaux AL, Giovannini M.

J Cell Sci. 2009 Nov 15;122(Pt 22):4141-9. doi: 10.1242/jcs.045914.

8.

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, Saotome I, O'Bryan JP, Gupta V, Ratner N, Der CJ, Jacks T, McClatchey AI.

Dev Cell. 2001 Jul;1(1):63-72.

9.

Missense mutations in the NF2 gene result in the quantitative loss of merlin protein and minimally affect protein intrinsic function.

Yang C, Asthagiri AR, Iyer RR, Lu J, Xu DS, Ksendzovsky A, Brady RO, Zhuang Z, Lonser RR.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4980-5. doi: 10.1073/pnas.1102198108. Epub 2011 Mar 7.

10.

Regulation of mTOR complex 2 signaling in neurofibromatosis 2-deficient target cell types.

James MF, Stivison E, Beauchamp R, Han S, Li H, Wallace MR, Gusella JF, Stemmer-Rachamimov AO, Ramesh V.

Mol Cancer Res. 2012 May;10(5):649-59. doi: 10.1158/1541-7786.MCR-11-0425-T. Epub 2012 Mar 16.

11.

Merlin/NF2 regulates angiogenesis in schwannomas through a Rac1/semaphorin 3F-dependent mechanism.

Wong HK, Shimizu A, Kirkpatrick ND, Garkavtsev I, Chan AW, di Tomaso E, Klagsbrun M, Jain RK.

Neoplasia. 2012 Feb;14(2):84-94.

12.

The tumor suppressor merlin interacts with microtubules and modulates Schwann cell microtubule cytoskeleton.

Muranen T, Grönholm M, Lampin A, Lallemand D, Zhao F, Giovannini M, Carpén O.

Hum Mol Genet. 2007 Jul 15;16(14):1742-51. Epub 2007 Jun 12.

PMID:
17566081
13.

Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor gene.

Golovnina K, Blinov A, Akhmametyeva EM, Omelyanchuk LV, Chang LS.

BMC Evol Biol. 2005 Dec 2;5:69.

14.

Role of Merlin/NF2 inactivation in tumor biology.

Petrilli AM, Fernández-Valle C.

Oncogene. 2016 Feb 4;35(5):537-48. doi: 10.1038/onc.2015.125. Epub 2015 Apr 20. Review.

15.

Functional analysis of neurofibromatosis 2 (NF2) missense mutations.

Gutmann DH, Hirbe AC, Haipek CA.

Hum Mol Genet. 2001 Jul 1;10(14):1519-29.

PMID:
11448944
16.

Point mutation in the NF2 gene of HEI-193 human schwannoma cells results in the expression of a merlin isoform with attenuated growth suppressive activity.

Lepont P, Stickney JT, Foster LA, Meng JJ, Hennigan RF, Ip W.

Mutat Res. 2008 Jan 1;637(1-2):142-51. Epub 2007 Aug 6.

17.

The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP.

Striedinger K, VandenBerg SR, Baia GS, McDermott MW, Gutmann DH, Lal A.

Neoplasia. 2008 Nov;10(11):1204-12.

18.

Molecular insights into NF2/Merlin tumor suppressor function.

Cooper J, Giancotti FG.

FEBS Lett. 2014 Aug 19;588(16):2743-52. doi: 10.1016/j.febslet.2014.04.001. Epub 2014 Apr 12. Review.

19.

Calpain-dependent proteolysis of NF2 protein: involvement in schwannomas and meningiomas.

Kimura Y, Saya H, Nakao M.

Neuropathology. 2000 Sep;20(3):153-60. Review.

PMID:
11132929
20.

Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function.

Surace EI, Haipek CA, Gutmann DH.

Oncogene. 2004 Jan 15;23(2):580-7.

PMID:
14724586

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