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Items: 1 to 20 of 86

1.

PI3K regulates branch initiation and extension of cultured mammary epithelia via Akt and Rac1 respectively.

Zhu W, Nelson CM.

Dev Biol. 2013 Jul 15;379(2):235-45. doi: 10.1016/j.ydbio.2013.04.029. Epub 2013 May 7.

2.

Regulation of osteoclast apoptosis and motility by small GTPase binding protein Rac1.

Fukuda A, Hikita A, Wakeyama H, Akiyama T, Oda H, Nakamura K, Tanaka S.

J Bone Miner Res. 2005 Dec;20(12):2245-53. Epub 2005 Aug 22.

3.

mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.

Morrison MM, Young CD, Wang S, Sobolik T, Sanchez VM, Hicks DJ, Cook RS, Brantley-Sieders DM.

PLoS Genet. 2015 Jul 1;11(7):e1005291. doi: 10.1371/journal.pgen.1005291. eCollection 2015 Jul.

4.

Expression and functional role of sprouty-2 in breast morphogenesis.

Sigurdsson V, Ingthorsson S, Hilmarsdottir B, Gustafsdottir SM, Franzdottir SR, Arason AJ, Steingrimsson E, Magnusson MK, Gudjonsson T.

PLoS One. 2013;8(4):e60798. doi: 10.1371/journal.pone.0060798. Epub 2013 Apr 3.

5.

Impaired cell death and mammary gland involution in the absence of Dock1 and Rac1 signaling.

Bagci H, Laurin M, Huber J, Muller WJ, Côté JF.

Cell Death Dis. 2014 Aug 14;5:e1375. doi: 10.1038/cddis.2014.338.

6.

PI3K signaling in the regulation of branching morphogenesis.

Zhu W, Nelson CM.

Biosystems. 2012 Sep;109(3):403-11. doi: 10.1016/j.biosystems.2012.04.004. Epub 2012 Apr 21. Review.

PMID:
22525052
7.

Rac1 is essential for basement membrane-dependent epiblast survival.

He X, Liu J, Qi Y, Brakebusch C, Chrostek-Grashoff A, Edgar D, Yurchenco PD, Corbett SA, Lowry SF, Graham AM, Han Y, Li S.

Mol Cell Biol. 2010 Jul;30(14):3569-81. doi: 10.1128/MCB.01366-09. Epub 2010 May 10.

8.

Prolactin and transforming growth factor-beta signaling exert opposing effects on mammary gland morphogenesis, involution, and the Akt-forkhead pathway.

Bailey JP, Nieport KM, Herbst MP, Srivastava S, Serra RA, Horseman ND.

Mol Endocrinol. 2004 May;18(5):1171-84. Epub 2004 Feb 12.

PMID:
14963111
9.

Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.

Tanaka S, Fukumoto Y, Nochioka K, Minami T, Kudo S, Shiba N, Takai Y, Williams CL, Liao JK, Shimokawa H.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1591-600. doi: 10.1161/ATVBAHA.112.300922. Epub 2013 May 2.

10.

Stearic acid suppresses mammary gland development by inhibiting PI3K/Akt signaling pathway through GPR120 in pubertal mice.

Meng Y, Yuan C, Zhang J, Zhang F, Fu Q, Zhu X, Shu G, Wang L, Gao P, Xi Q, Sun J, Zhang Y, Jiang Q, Wang S.

Biochem Biophys Res Commun. 2017 Sep 9;491(1):192-197. doi: 10.1016/j.bbrc.2017.07.075. Epub 2017 Jul 13.

PMID:
28712865
11.

Distinct roles of class IA PI3K isoforms in primary and immortalised macrophages.

Papakonstanti EA, Zwaenepoel O, Bilancio A, Burns E, Nock GE, Houseman B, Shokat K, Ridley AJ, Vanhaesebroeck B.

J Cell Sci. 2008 Dec 15;121(Pt 24):4124-33. doi: 10.1242/jcs.032763. Epub 2008 Nov 25.

12.
13.

Crumbs controls epithelial integrity by inhibiting Rac1 and PI3K.

Chartier FJ, Hardy ÉJ, Laprise P.

J Cell Sci. 2011 Oct 15;124(Pt 20):3393-8. doi: 10.1242/jcs.092601. Epub 2011 Oct 7.

14.

Modulation of fibroblast growth factor signaling is essential for mammary epithelial morphogenesis.

Zhang X, Qiao G, Lu P.

PLoS One. 2014 Apr 9;9(4):e92735. doi: 10.1371/journal.pone.0092735. eCollection 2014.

15.
16.

HO-1-STAT3 axis in mouse liver ischemia/reperfusion injury: regulation of TLR4 innate responses through PI3K/PTEN signaling.

Ke B, Shen XD, Ji H, Kamo N, Gao F, Freitas MC, Busuttil RW, Kupiec-Weglinski JW.

J Hepatol. 2012 Feb;56(2):359-66. doi: 10.1016/j.jhep.2011.05.023. Epub 2011 Jul 12.

17.

PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice.

Wu CY, Carpenter ES, Takeuchi KK, Halbrook CJ, Peverley LV, Bien H, Hall JC, DelGiorno KE, Pal D, Song Y, Shi C, Lin RZ, Crawford HC.

Gastroenterology. 2014 Dec;147(6):1405-16.e7. doi: 10.1053/j.gastro.2014.08.032. Epub 2014 Aug 27.

18.
20.

Rac1 mediates morphogenetic responses to intercellular signals in the gastrulating mouse embryo.

Migeotte I, Grego-Bessa J, Anderson KV.

Development. 2011 Jul;138(14):3011-20. doi: 10.1242/dev.059766.

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