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Items: 1 to 20 of 85


Domain-domain interactions in filamin A (16-23) impose a hierarchy of unfolding forces.

Xu T, Lannon H, Wolf S, Nakamura F, Brujic J.

Biophys J. 2013 May 7;104(9):2022-30. doi: 10.1016/j.bpj.2013.03.034.


Mechanical perturbation of filamin A immunoglobulin repeats 20-21 reveals potential non-equilibrium mechanochemical partner binding function.

Chen H, Chandrasekar S, Sheetz MP, Stossel TP, Nakamura F, Yan J.

Sci Rep. 2013;3:1642. doi: 10.1038/srep01642.


Differential mechanical stability of filamin A rod segments.

Chen H, Zhu X, Cong P, Sheetz MP, Nakamura F, Yan J.

Biophys J. 2011 Sep 7;101(5):1231-7. doi: 10.1016/j.bpj.2011.07.028.


Structural basis of filamin A functions.

Nakamura F, Osborn TM, Hartemink CA, Hartwig JH, Stossel TP.

J Cell Biol. 2007 Dec 3;179(5):1011-25.


Documentation and localization of force-mediated filamin A domain perturbations in moving cells.

Nakamura F, Song M, Hartwig JH, Stossel TP.

Nat Commun. 2014 Aug 14;5:4656. doi: 10.1038/ncomms5656.


Measuring molecular rupture forces between single actin filaments and actin-binding proteins.

Ferrer JM, Lee H, Chen J, Pelz B, Nakamura F, Kamm RD, Lang MJ.

Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9221-6. doi: 10.1073/pnas.0706124105. Epub 2008 Jun 30.


Filamin A interacts with the coactivator MKL1 to promote the activity of the transcription factor SRF and cell migration.

Kircher P, Hermanns C, Nossek M, Drexler MK, Grosse R, Fischer M, Sarikas A, Penkava J, Lewis T, Prywes R, Gudermann T, Muehlich S.

Sci Signal. 2015 Nov 10;8(402):ra112. doi: 10.1126/scisignal.aad2959.


Filamin-a increases the stability and plasma membrane expression of polycystin-2.

Wang Q, Zheng W, Wang Z, Yang J, Hussein S, Tang J, Chen XZ.

PLoS One. 2015 Apr 10;10(4):e0123018. doi: 10.1371/journal.pone.0123018. eCollection 2015.


Electron microscopy and 3D reconstruction reveals filamin Ig domain binding to F-actin.

Suphamungmee W, Nakamura F, Hartwig JH, Lehman W.

J Mol Biol. 2012 Dec 14;424(5):248-56. doi: 10.1016/j.jmb.2012.09.025. Epub 2012 Oct 4.


The role of FilGAP-filamin A interactions in mechanoprotection.

Shifrin Y, Arora PD, Ohta Y, Calderwood DA, McCulloch CA.

Mol Biol Cell. 2009 Mar;20(5):1269-79. doi: 10.1091/mbc.E08-08-0872. Epub 2009 Jan 14.


An adventitious interaction of filamin A with RhoGDI2(Tyr153Glu).

Song M, He Q, Berk BA, Hartwig JH, Stossel TP, Nakamura F.

Biochem Biophys Res Commun. 2016 Jan 15;469(3):659-64. doi: 10.1016/j.bbrc.2015.12.044. Epub 2015 Dec 17.


Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells.

Flanagan LA, Chou J, Falet H, Neujahr R, Hartwig JH, Stossel TP.

J Cell Biol. 2001 Nov 12;155(4):511-7. Epub 2001 Nov 12.


Kinetic Ductility and Force-Spike Resistance of Proteins from Single-Molecule Force Spectroscopy.

Cossio P, Hummer G, Szabo A.

Biophys J. 2016 Aug 23;111(4):832-840. doi: 10.1016/j.bpj.2016.05.054.


Amino- and carboxyl-terminal domains of Filamin-A interact with CRMP1 to mediate Sema3A signalling.

Nakamura F, Kumeta K, Hida T, Isono T, Nakayama Y, Kuramata-Matsuoka E, Yamashita N, Uchida Y, Ogura K, Gengyo-Ando K, Mitani S, Ogino T, Goshima Y.

Nat Commun. 2014 Oct 31;5:5325. doi: 10.1038/ncomms6325.


1H, 13C and 15N resonance assignments of the human filamin A tandem immunoglobulin-like domains 16-17 and 18-19.

Heikkinen O, Permi P, Koskela H, Ylänne J, Kilpeläinen I.

Biomol NMR Assign. 2009 Jun;3(1):53-6. doi: 10.1007/s12104-008-9140-6. Epub 2009 Jan 4.


Complex unfolding kinetics of single-domain proteins in the presence of force.

Schlierf M, Yew ZT, Rief M, Paci E.

Biophys J. 2010 Sep 8;99(5):1620-7. doi: 10.1016/j.bpj.2010.06.039.


A mechanical unfolding intermediate in an actin-crosslinking protein.

Schwaiger I, Kardinal A, Schleicher M, Noegel AA, Rief M.

Nat Struct Mol Biol. 2004 Jan;11(1):81-5. Epub 2003 Dec 29.


Filamin A protects cells against force-induced apoptosis by stabilizing talin- and vinculin-containing cell adhesions.

Pinto VI, Senini VW, Wang Y, Kazembe MP, McCulloch CA.

FASEB J. 2014 Jan;28(1):453-63. doi: 10.1096/fj.13-233759. Epub 2013 Oct 4.


ADP-ribosylation factor-like 4C binding to filamin-A modulates filopodium formation and cell migration.

Chiang TS, Wu HF, Lee FS.

Mol Biol Cell. 2017 Nov 1;28(22):3013-3028. doi: 10.1091/mbc.E17-01-0059. Epub 2017 Aug 30.

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