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Items: 1 to 20 of 97

1.

TGF-β signaling in myeloid cells is required for tumor metastasis.

Pang Y, Gara SK, Achyut BR, Li Z, Yan HH, Day CP, Weiss JM, Trinchieri G, Morris JC, Yang L.

Cancer Discov. 2013 Aug;3(8):936-51. doi: 10.1158/2159-8290.CD-12-0527. Epub 2013 May 9.

2.

Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties.

Novitskiy SV, Pickup MW, Chytil A, Polosukhina D, Owens P, Moses HL.

J Leukoc Biol. 2012 Sep;92(3):641-51. doi: 10.1189/jlb.1211639. Epub 2012 Jun 8.

3.

Role of TGF-β signaling in generation of CD39+CD73+ myeloid cells in tumors.

Ryzhov SV, Pickup MW, Chytil A, Gorska AE, Zhang Q, Owens P, Feoktistov I, Moses HL, Novitskiy SV.

J Immunol. 2014 Sep 15;193(6):3155-64. doi: 10.4049/jimmunol.1400578. Epub 2014 Aug 15.

4.

TGF-beta receptor type-2 expression in cancer-associated fibroblasts regulates breast cancer cell growth and survival and is a prognostic marker in pre-menopausal breast cancer.

Busch S, Acar A, Magnusson Y, Gregersson P, Rydén L, Landberg G.

Oncogene. 2015 Jan 2;34(1):27-38. doi: 10.1038/onc.2013.527. Epub 2013 Dec 16.

PMID:
24336330
5.

Myeloid TGF-β responsiveness promotes metastases.

Souza-Fonseca-Guimaraes F, Smyth MJ.

Cancer Discov. 2013 Aug;3(8):846-8. doi: 10.1158/2159-8290.CD-13-0271.

6.

Lack of transforming growth factor-β signaling promotes collective cancer cell invasion through tumor-stromal crosstalk.

Matise LA, Palmer TD, Ashby WJ, Nashabi A, Chytil A, Aakre M, Pickup MW, Gorska AE, Zijlstra A, Moses HL.

Breast Cancer Res. 2012 Jul 2;14(4):R98. doi: 10.1186/bcr3217.

7.

Fibulin-3 is a novel TGF-β pathway inhibitor in the breast cancer microenvironment.

Tian H, Liu J, Chen J, Gatza ML, Blobe GC.

Oncogene. 2015 Nov 5;34(45):5635-47. doi: 10.1038/onc.2015.13. Epub 2015 Mar 30.

8.

Loss of one Tgfbr2 allele in fibroblasts promotes metastasis in MMTV: polyoma middle T transgenic and transplant mouse models of mammary tumor progression.

Fang WB, Jokar I, Chytil A, Moses HL, Abel T, Cheng N.

Clin Exp Metastasis. 2011 Apr;28(4):351-66. doi: 10.1007/s10585-011-9373-0. Epub 2011 Mar 4.

9.

MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-κB and TGF-β signaling pathways.

Keklikoglou I, Koerner C, Schmidt C, Zhang JD, Heckmann D, Shavinskaya A, Allgayer H, Gückel B, Fehm T, Schneeweiss A, Sahin O, Wiemann S, Tschulena U.

Oncogene. 2012 Sep 13;31(37):4150-63. doi: 10.1038/onc.2011.571. Epub 2011 Dec 12.

PMID:
22158050
10.

Homeoprotein Six1 increases TGF-beta type I receptor and converts TGF-beta signaling from suppressive to supportive for tumor growth.

Micalizzi DS, Wang CA, Farabaugh SM, Schiemann WP, Ford HL.

Cancer Res. 2010 Dec 15;70(24):10371-80. doi: 10.1158/0008-5472.CAN-10-1354. Epub 2010 Nov 5.

11.
12.

Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis.

Yang L, Huang J, Ren X, Gorska AE, Chytil A, Aakre M, Carbone DP, Matrisian LM, Richmond A, Lin PC, Moses HL.

Cancer Cell. 2008 Jan;13(1):23-35. doi: 10.1016/j.ccr.2007.12.004.

13.

TGF-β modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment.

Yeung TL, Leung CS, Wong KK, Samimi G, Thompson MS, Liu J, Zaid TM, Ghosh S, Birrer MJ, Mok SC.

Cancer Res. 2013 Aug 15;73(16):5016-28. doi: 10.1158/0008-5472.CAN-13-0023. Epub 2013 Jul 3.

14.

Transforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 loss.

Morris SM, Baek JY, Koszarek A, Kanngurn S, Knoblaugh SE, Grady WM.

Hepatology. 2012 Jan;55(1):121-31. doi: 10.1002/hep.24653. Epub 2011 Dec 6.

15.

Inactivation of TGF-β signaling and loss of PTEN cooperate to induce colon cancer in vivo.

Yu M, Trobridge P, Wang Y, Kanngurn S, Morris SM, Knoblaugh S, Grady WM.

Oncogene. 2014 Mar 20;33(12):1538-47. doi: 10.1038/onc.2013.102. Epub 2013 Apr 22.

16.

Loss of TGF-β responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions.

Li X, Sterling JA, Fan KH, Vessella RL, Shyr Y, Hayward SW, Matrisian LM, Bhowmick NA.

Mol Cancer Res. 2012 Apr;10(4):494-503. doi: 10.1158/1541-7786.MCR-11-0506. Epub 2012 Jan 30.

17.

A reciprocal role of prostate cancer on stromal DNA damage.

Banerjee J, Mishra R, Li X, Jackson RS 2nd, Sharma A, Bhowmick NA.

Oncogene. 2014 Oct 9;33(41):4924-31. doi: 10.1038/onc.2013.431. Epub 2013 Oct 21.

18.

AKT hyperactivation confers a Th1 phenotype in thymic Treg cells deficient in TGF-β receptor II signaling.

Liu Y, Xu Y, Sun J, Ma A, Zhang F, Xia S, Xu G, Liu Y.

Eur J Immunol. 2014 Feb;44(2):521-32. doi: 10.1002/eji.201243291. Epub 2013 Dec 2.

20.

Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis.

Li X, Placencio V, Iturregui JM, Uwamariya C, Sharif-Afshar AR, Koyama T, Hayward SW, Bhowmick NA.

Oncogene. 2008 Nov 27;27(56):7118-30. doi: 10.1038/onc.2008.293. Epub 2008 Aug 25.

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