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Items: 1 to 20 of 96

1.

Reversal of the substrate specificity of CMP N-glycosidase to dCMP.

Sikowitz MD, Cooper LE, Begley TP, Kaminski PA, Ealick SE.

Biochemistry. 2013 Jun 11;52(23):4037-47. doi: 10.1021/bi400316p. Epub 2013 May 28.

2.

Structure of the N-glycosidase MilB in complex with hydroxymethyl CMP reveals its Arg23 specifically recognizes the substrate and controls its entry.

Zhao G, Wu G, Zhang Y, Liu G, Han T, Deng Z, He X.

Nucleic Acids Res. 2014 Jul;42(12):8115-24. doi: 10.1093/nar/gku486. Epub 2014 Jun 11.

3.

Sugar specificity of bacterial CMP kinases as revealed by crystal structures and mutagenesis of Escherichia coli enzyme.

Bertrand T, Briozzo P, Assairi L, Ofiteru A, Bucurenci N, Munier-Lehmann H, Golinelli-Pimpaneau B, Bârzu O, Gilles AM.

J Mol Biol. 2002 Feb 1;315(5):1099-110.

PMID:
11827479
4.
5.

Dissecting cobamide diversity through structural and functional analyses of the base-activating CobT enzyme of Salmonella enterica.

Chan CH, Newmister SA, Talyor K, Claas KR, Rayment I, Escalante-Semerena JC.

Biochim Biophys Acta. 2014 Jan;1840(1):464-75. doi: 10.1016/j.bbagen.2013.09.038. Epub 2013 Oct 10.

6.

Structural analyses reveal two distinct families of nucleoside phosphorylases.

Pugmire MJ, Ealick SE.

Biochem J. 2002 Jan 1;361(Pt 1):1-25. Review.

7.

The mildiomycin biosynthesis: initial steps for sequential generation of 5-hydroxymethylcytidine 5'-monophosphate and 5-hydroxymethylcytosine in Streptoverticillium rimofaciens ZJU5119.

Li L, Xu Z, Xu X, Wu J, Zhang Y, He X, Zabriskie TM, Deng Z.

Chembiochem. 2008 May 23;9(8):1286-94. doi: 10.1002/cbic.200800008.

PMID:
18412191
8.

In vivo reshaping the catalytic site of nucleoside 2'-deoxyribosyltransferase for dideoxy- and didehydronucleosides via a single amino acid substitution.

Kaminski PA, Dacher P, Dugué L, Pochet S.

J Biol Chem. 2008 Jul 18;283(29):20053-9. doi: 10.1074/jbc.M802706200. Epub 2008 May 16.

9.
10.

Crystal structure of the polyketide cyclase AknH with bound substrate and product analogue: implications for catalytic mechanism and product stereoselectivity.

Kallio P, Sultana A, Niemi J, Mäntsälä P, Schneider G.

J Mol Biol. 2006 Mar 17;357(1):210-20. Epub 2006 Jan 6.

PMID:
16414075
11.

Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism.

Xu Y, Nakajima Y, Ito K, Zheng H, Oyama H, Heiser U, Hoffmann T, Gärtner UT, Demuth HU, Yoshimoto T.

J Mol Biol. 2008 Jan 18;375(3):708-19. Epub 2007 Oct 3.

PMID:
18042490
12.
13.

Structural basis for the divergence of substrate specificity and biological function within HAD phosphatases in lipopolysaccharide and sialic acid biosynthesis.

Daughtry KD, Huang H, Malashkevich V, Patskovsky Y, Liu W, Ramagopal U, Sauder JM, Burley SK, Almo SC, Dunaway-Mariano D, Allen KN.

Biochemistry. 2013 Aug 13;52(32):5372-86. doi: 10.1021/bi400659k. Epub 2013 Jul 29.

14.
15.

Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1.

Puthan Veetil V, Raj H, Quax WJ, Janssen DB, Poelarends GJ.

FEBS J. 2009 Jun;276(11):2994-3007. doi: 10.1111/j.1742-4658.2009.07015.x. Epub 2009 Apr 16.

16.

Regiospecific formation of cobamide isomers is directed by CobT.

Crofts TS, Hazra AB, Tran JL, Sokolovskaya OM, Osadchiy V, Ad O, Pelton J, Bauer S, Taga ME.

Biochemistry. 2014 Dec 16;53(49):7805-15. doi: 10.1021/bi501147d. Epub 2014 Dec 5.

PMID:
25412146
17.

Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis.

Schmölzer K, Ribitsch D, Czabany T, Luley-Goedl C, Kokot D, Lyskowski A, Zitzenbacher S, Schwab H, Nidetzky B.

Glycobiology. 2013 Nov;23(11):1293-304. doi: 10.1093/glycob/cwt066. Epub 2013 Aug 22.

18.

Crystal structures of two aromatic hydroxylases involved in the early tailoring steps of angucycline biosynthesis.

Koskiniemi H, Metsä-Ketelä M, Dobritzsch D, Kallio P, Korhonen H, Mäntsälä P, Schneider G, Niemi J.

J Mol Biol. 2007 Sep 21;372(3):633-48. Epub 2007 Jul 10.

PMID:
17669423
19.
20.

Crystal structures of Streptococcus mutans 2'-deoxycytidylate deaminase and its complex with substrate analog and allosteric regulator dCTP x Mg2+.

Hou HF, Liang YH, Li LF, Su XD, Dong YH.

J Mol Biol. 2008 Mar 14;377(1):220-31. doi: 10.1016/j.jmb.2007.12.064. Epub 2008 Jan 5.

PMID:
18255096
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