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Items: 1 to 20 of 82

1.

New modalities in conformationally constrained peptides for potency, selectivity and cell permeation.

Dharanipragada R.

Future Med Chem. 2013 May;5(7):831-49. doi: 10.4155/fmc.13.25. Review.

PMID:
23651095
2.

Synthesis of chemically modified bioactive peptides: recent advances, challenges and developments for medicinal chemistry.

Gracia SR, Gaus K, Sewald N.

Future Med Chem. 2009 Oct;1(7):1289-310. doi: 10.4155/fmc.09.97. Review.

PMID:
21426104
3.

Chemical modification of conotoxins to improve stability and activity.

Craik DJ, Adams DJ.

ACS Chem Biol. 2007 Jul 20;2(7):457-68. Review.

PMID:
17649970
4.

Strategies for the development of conotoxins as new therapeutic leads.

Brady RM, Baell JB, Norton RS.

Mar Drugs. 2013 Jun 28;11(7):2293-313. doi: 10.3390/md11072293. Review.

5.

Critical effect of peptide cyclization on the potency of peptide inhibitors against Dengue virus NS2B-NS3 protease.

Xu S, Li H, Shao X, Fan C, Ericksen B, Liu J, Chi C, Wang C.

J Med Chem. 2012 Aug 9;55(15):6881-7. doi: 10.1021/jm300655h. Epub 2012 Jul 23.

PMID:
22780881
6.

Macrocycles as protein-protein interaction inhibitors.

Dougherty PG, Qian Z, Pei D.

Biochem J. 2017 Mar 15;474(7):1109-1125. doi: 10.1042/BCJ20160619. Review.

PMID:
28298556
7.
8.

The future of peptide-based drugs.

Craik DJ, Fairlie DP, Liras S, Price D.

Chem Biol Drug Des. 2013 Jan;81(1):136-47. doi: 10.1111/cbdd.12055. Review.

PMID:
23253135
9.

Oral absorption and in vivo biodistribution of alpha-conotoxin MII and a lipidic analogue.

Blanchfield JT, Gallagher OP, Cros C, Lewis RJ, Alewood PF, Toth I.

Biochem Biophys Res Commun. 2007 Sep 14;361(1):97-102. Epub 2007 Jul 20.

PMID:
17640618
10.

Peptides and peptide conjugates: therapeutics on the upward path.

Ahrens VM, Bellmann-Sickert K, Beck-Sickinger AG.

Future Med Chem. 2012 Aug;4(12):1567-86. doi: 10.4155/fmc.12.76. Review.

PMID:
22917246
11.

Cyclization of conotoxins to improve their biopharmaceutical properties.

Clark RJ, Akcan M, Kaas Q, Daly NL, Craik DJ.

Toxicon. 2012 Mar 15;59(4):446-55. doi: 10.1016/j.toxicon.2010.12.003. Epub 2010 Dec 10. Review.

PMID:
21147143
12.

Polymer-based oral peptide nanomedicines.

Herrero EP, Alonso MJ, Csaba N.

Ther Deliv. 2012 May;3(5):657-68. Review.

PMID:
22834409
13.

Prodrug approaches to the improved delivery of peptide drugs.

Wang W, Jiang J, Ballard CE, Wang B.

Curr Pharm Des. 1999 Apr;5(4):265-87. Review.

PMID:
10101225
14.

N- and C-terminal extensions of μ-conotoxins increase potency and selectivity for neuronal sodium channels.

Schroeder CI, Adams D, Thomas L, Alewood PF, Lewis RJ.

Biopolymers. 2012;98(2):161-5. doi: 10.1002/bip.22032. Epub 2012 Feb 10.

PMID:
22733528
15.

Conformational stability of collagen triple helices functionalized in the Yaa position by click chemistry.

Erdmann RS, Wennemers H.

Org Biomol Chem. 2012 Mar 14;10(10):1982-6. doi: 10.1039/c2ob06720j. Epub 2012 Jan 20.

PMID:
22266764
16.

Peptides as therapeutics with enhanced bioactivity.

Goodwin D, Simerska P, Toth I.

Curr Med Chem. 2012;19(26):4451-61. Review.

PMID:
22830348
17.

Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor.

Halai R, Callaghan B, Daly NL, Clark RJ, Adams DJ, Craik DJ.

J Med Chem. 2011 Oct 13;54(19):6984-92. doi: 10.1021/jm201060r. Epub 2011 Sep 15.

PMID:
21888386
18.

Conformationally constrained peptides as protein tyrosine kinase inhibitors.

Tiwari RK, Parang K.

Curr Pharm Des. 2012;18(20):2852-66. Review.

PMID:
22571654
19.

Directed modulation of protein kinase C isozyme selectivity with bisubstrate-based inhibitors.

van Wandelen LT, van Ameijde J, Mady AS, Wammes AE, Bode A, Poot AJ, Ruijtenbeek R, Liskamp RM.

ChemMedChem. 2012 Dec;7(12):2113-21. doi: 10.1002/cmdc.201200349. Epub 2012 Nov 8.

PMID:
23139239
20.

Synthesis and evaluation of conformationally constrained peptide analogues as the Src SH3 domain binding ligands.

Tiwari R, Brown A, Narramaneni S, Sun G, Parang K.

Biochimie. 2010 Sep;92(9):1153-63. doi: 10.1016/j.biochi.2010.01.017. Epub 2010 Jan 28.

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