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Items: 1 to 20 of 92

1.

Edaravone protects against glutamate-induced PERK/EIF2α/ATF4 integrated stress response and activation of caspase-12.

Fan J, Long H, Li Y, Liu Y, Zhou W, Li Q, Yin G, Zhang N, Cai W.

Brain Res. 2013 Jun 26;1519:1-8. doi: 10.1016/j.brainres.2013.04.037. Epub 2013 May 3.

PMID:
23648361
2.

Protective effects of the free radical scavenger edaravone against glutamate neurotoxicity in nearly pure neuronal culture.

Hisano K, Watanabe M, Morimoto Y.

J Anesth. 2009;23(3):363-9. doi: 10.1007/s00540-009-0766-z. Epub 2009 Aug 14.

PMID:
19685116
3.

Edaravone protects cortical neurons from apoptosis by inhibiting the translocation of BAX and Increasing the interaction between 14-3-3 and p-BAD.

Fan J, Zhang N, Yin G, Zhang Z, Cheng G, Qian W, Long H, Cai W.

Int J Neurosci. 2012 Nov;122(11):665-74. doi: 10.3109/00207454.2012.707714. Epub 2012 Aug 21.

PMID:
22757651
4.

[The study of the protective effect and its mechanism of Edaravone to neurons with hydrogen peroxide stimulated].

Long H, Zhang N, Fan J, Li QQ, Li YM, Tang J, Cheng G, Yin GY, Cai WH.

Zhonghua Wai Ke Za Zhi. 2013 Mar;51(3):266-71. Chinese.

PMID:
23859332
5.

EIF2alpha and caspase-12 activation are involved in oxygen-glucose-serum deprivation/restoration-induced apoptosis of spinal cord astrocytes.

Zhang A, Zhang J, Sun P, Yao C, Su C, Sui T, Huang H, Cao X, Ge Y.

Neurosci Lett. 2010 Jun 30;478(1):32-6. doi: 10.1016/j.neulet.2010.04.062. Epub 2010 May 2.

PMID:
20444431
6.

Edaravone protects against hypoxia/ischemia-induced endoplasmic reticulum dysfunction.

Qi X, Okuma Y, Hosoi T, Nomura Y.

J Pharmacol Exp Ther. 2004 Oct;311(1):388-93. Epub 2004 Jun 3.

7.

Edaravone protects against oxygen-glucose-serum deprivation/restoration-induced apoptosis in spinal cord astrocytes by inhibiting integrated stress response.

Dai B, Yan T, Shen YX, Xu YJ, Shen HB, Chen D, Wang JR, He SH, Dong QR, Zhang AL.

Neural Regen Res. 2017 Feb;12(2):283-289. doi: 10.4103/1673-5374.199006.

8.

Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA.

Galehdar Z, Swan P, Fuerth B, Callaghan SM, Park DS, Cregan SP.

J Neurosci. 2010 Dec 15;30(50):16938-48. doi: 10.1523/JNEUROSCI.1598-10.2010.

9.

Edaravone, a potent free radical scavenger, prevents anthracycline-induced myocardial cell death.

Ikegami E, Fukazawa R, Kanbe M, Watanabe M, Abe M, Watanabe M, Kamisago M, Hajikano M, Katsube Y, Ogawa S.

Circ J. 2007 Nov;71(11):1815-20.

10.

Edaravone offers neuroprotection in a diabetic stroke model via inhibition of endoplasmic reticulum stress.

Srinivasan K, Sharma SS.

Basic Clin Pharmacol Toxicol. 2012 Feb;110(2):133-40. doi: 10.1111/j.1742-7843.2011.00763.x. Epub 2011 Aug 18.

11.

The free radical scavenger edaravone rescues rats from cerebral infarction by attenuating the release of high-mobility group box-1 in neuronal cells.

Kikuchi K, Kawahara K, Tancharoen S, Matsuda F, Morimoto Y, Ito T, Biswas KK, Takenouchi K, Miura N, Oyama Y, Nawa Y, Arimura N, Iwata M, Tajima Y, Kuramoto T, Nakayama K, Shigemori M, Yoshida Y, Hashiguchi T, Maruyama I.

J Pharmacol Exp Ther. 2009 Jun;329(3):865-74. doi: 10.1124/jpet.108.149484. Epub 2009 Mar 17.

12.

Selective inhibition of eukaryotic translation initiation factor 2 alpha dephosphorylation potentiates fatty acid-induced endoplasmic reticulum stress and causes pancreatic beta-cell dysfunction and apoptosis.

Cnop M, Ladriere L, Hekerman P, Ortis F, Cardozo AK, Dogusan Z, Flamez D, Boyce M, Yuan J, Eizirik DL.

J Biol Chem. 2007 Feb 9;282(6):3989-97. Epub 2006 Dec 8.

13.

The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers.

Li F, Hayashi T, Jin G, Deguchi K, Nagotani S, Nagano I, Shoji M, Chan PH, Abe K.

Brain Res. 2005 Jun 28;1048(1-2):59-68.

PMID:
15921666
14.

Edaravone protects HT22 neurons from H2O2-induced apoptosis by inhibiting the MAPK signaling pathway.

Zhao ZY, Luan P, Huang SX, Xiao SH, Zhao J, Zhang B, Gu BB, Pi RB, Liu J.

CNS Neurosci Ther. 2013 Mar;19(3):163-9. doi: 10.1111/cns.12044. Epub 2012 Dec 18.

PMID:
23253171
15.

Endoplasmic reticulum stress implicated in the development of renal fibrosis.

Chiang CK, Hsu SP, Wu CT, Huang JW, Cheng HT, Chang YW, Hung KY, Wu KD, Liu SH.

Mol Med. 2011;17(11-12):1295-305. doi: 10.2119/molmed.2011.00131. Epub 2011 Aug 19.

16.

[Effects of edaravone on IRE1 mRNA expression and neuronal apoptosis in the hippocampus of rats with status convulsivus].

Jiao Y, Deng XL, Li GQ.

Zhongguo Dang Dai Er Ke Za Zhi. 2009 Jun;11(6):471-5. Chinese.

17.

Free-radical scavenger edaravone treatment confers neuroprotection against traumatic brain injury in rats.

Wang GH, Jiang ZL, Li YC, Li X, Shi H, Gao YQ, Vosler PS, Chen J.

J Neurotrauma. 2011 Oct;28(10):2123-34. doi: 10.1089/neu.2011.1939. Epub 2011 Sep 27.

18.

The antioxidant edaravone attenuates ER-stress-mediated cardiac apoptosis and dysfunction in rats with autoimmune myocarditis.

Shimazaki H, Watanabe K, Veeraveedu PT, Harima M, Thandavarayan RA, Arozal W, Tachikawa H, Kodama M, Aizawa Y.

Free Radic Res. 2010 Sep;44(9):1082-90. doi: 10.3109/10715762.2010.499904.

PMID:
20815771
19.

Edaravone, a free radical scavenger, protects components of the neurovascular unit against oxidative stress in vitro.

Lee BJ, Egi Y, van Leyen K, Lo EH, Arai K.

Brain Res. 2010 Jan 11;1307:22-7. doi: 10.1016/j.brainres.2009.10.026. Epub 2009 Oct 17.

20.

Edaravone, a free radical scavenger, protects against retinal damage in vitro and in vivo.

Inokuchi Y, Imai S, Nakajima Y, Shimazawa M, Aihara M, Araie M, Hara H.

J Pharmacol Exp Ther. 2009 May;329(2):687-98. doi: 10.1124/jpet.108.148676. Epub 2009 Feb 6.

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