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Items: 1 to 20 of 49

1.

Small molecules interacting with α-synuclein: antiaggregating and cytoprotective properties.

Marchiani A, Mammi S, Siligardi G, Hussain R, Tessari I, Bubacco L, Delogu G, Fabbri D, Dettori MA, Sanna D, Dedola S, Serra PA, Ruzza P.

Amino Acids. 2013 Aug;45(2):327-38. doi: 10.1007/s00726-013-1503-3. Epub 2013 May 5.

PMID:
23645386
2.

Curcumin modulates α-synuclein aggregation and toxicity.

Singh PK, Kotia V, Ghosh D, Mohite GM, Kumar A, Maji SK.

ACS Chem Neurosci. 2013 Mar 20;4(3):393-407. doi: 10.1021/cn3001203. Epub 2012 Dec 17.

3.

Thermal stability, antioxidant, and anti-inflammatory activity of curcumin and its degradation product 4-vinyl guaiacol.

Esatbeyoglu T, Ulbrich K, Rehberg C, Rohn S, Rimbach G.

Food Funct. 2015 Mar;6(3):887-93. doi: 10.1039/c4fo00790e.

PMID:
25619943
4.
5.

Curcumin inhibits aggregation of alpha-synuclein.

Pandey N, Strider J, Nolan WC, Yan SX, Galvin JE.

Acta Neuropathol. 2008 Apr;115(4):479-89. doi: 10.1007/s00401-007-0332-4. Epub 2008 Jan 10.

PMID:
18189141
6.
7.

Synthesis of quinoline derivatives of tetrahydrocurcumin and zingerone and evaluation of their antioxidant and antibacterial attributes.

Manjunatha JR, Bettadaiah BK, Negi PS, Srinivas P.

Food Chem. 2013 Jan 15;136(2):650-8. doi: 10.1016/j.foodchem.2012.08.052. Epub 2012 Sep 13.

PMID:
23122110
8.

Design, synthesis, and biological evaluation of curcumin analogues as multifunctional agents for the treatment of Alzheimer's disease.

Chen SY, Chen Y, Li YP, Chen SH, Tan JH, Ou TM, Gu LQ, Huang ZS.

Bioorg Med Chem. 2011 Sep 15;19(18):5596-604. doi: 10.1016/j.bmc.2011.07.033. Epub 2011 Jul 24.

PMID:
21840724
9.

Effect of curcumin analogs onα-synuclein aggregation and cytotoxicity.

Jha NN, Ghosh D, Das S, Anoop A, Jacob RS, Singh PK, Ayyagari N, Namboothiri IN, Maji SK.

Sci Rep. 2016 Jun 24;6:28511. doi: 10.1038/srep28511.

10.
11.

On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of alpha-synuclein with Congo red and lacmoid.

Lendel C, Bertoncini CW, Cremades N, Waudby CA, Vendruscolo M, Dobson CM, Schenk D, Christodoulou J, Toth G.

Biochemistry. 2009 Sep 8;48(35):8322-34. doi: 10.1021/bi901285x.

PMID:
19645507
12.

Design, synthesis and anti-Alzheimer properties of dimethylaminomethyl-substituted curcumin derivatives.

Fang L, Gou S, Liu X, Cao F, Cheng L.

Bioorg Med Chem Lett. 2014 Jan 1;24(1):40-3. doi: 10.1016/j.bmcl.2013.12.011. Epub 2013 Dec 8.

PMID:
24342238
13.

An appraisal on recent medicinal perspective of curcumin degradant: Dehydrozingerone (DZG).

Hampannavar GA, Karpoormath R, Palkar MB, Shaikh MS.

Bioorg Med Chem. 2016 Feb 15;24(4):501-20. doi: 10.1016/j.bmc.2015.12.049. Epub 2016 Jan 2. Review.

PMID:
26796952
14.

Characterization of fibrillation process of alpha-synuclein at the initial stage.

Tashiro M, Kojima M, Kihara H, Kasai K, Kamiyoshihara T, Uéda K, Shimotakahara S.

Biochem Biophys Res Commun. 2008 May 9;369(3):910-4. doi: 10.1016/j.bbrc.2008.02.127. Epub 2008 Mar 7.

PMID:
18329380
15.

Rifampicin protects PC12 cells against MPP+-induced apoptosis and inhibits the expression of an alpha-Synuclein multimer.

Xu J, Wei C, Xu C, Bennett MC, Zhang G, Li F, Tao E.

Brain Res. 2007 Mar 30;1139:220-5. Epub 2007 Jan 4.

PMID:
17280646
16.

Age-dependent α-synuclein aggregation in the Microcebus murinus lemur primate.

Canron MH, Perret M, Vital A, Bézard E, Dehay B.

Sci Rep. 2012;2:910. doi: 10.1038/srep00910. Epub 2012 Nov 30.

17.

Blockade of enzyme activity inhibits tissue transglutaminase-mediated transamidation of α-synuclein in a cellular model of Parkinson's disease.

Verhaar R, Jongenelen CA, Gerard M, Baekelandt V, Van Dam AM, Wilhelmus MM, Drukarch B.

Neurochem Int. 2011 Jun;58(7):785-93. doi: 10.1016/j.neuint.2011.03.004. Epub 2011 Mar 31.

PMID:
21440023
18.

Raised calcium promotes α-synuclein aggregate formation.

Nath S, Goodwin J, Engelborghs Y, Pountney DL.

Mol Cell Neurosci. 2011 Feb;46(2):516-26. doi: 10.1016/j.mcn.2010.12.004. Epub 2010 Dec 9.

PMID:
21145971
19.

Alpha-synuclein, Parkinson's disease, and Alzheimer's disease.

Kim S, Seo JH, Suh YH.

Parkinsonism Relat Disord. 2004 May;10 Suppl 1:S9-13. Review.

PMID:
15109581
20.

Linker histone H1 binds to disease associated amyloid-like fibrils.

Duce JA, Smith DP, Blake RE, Crouch PJ, Li QX, Masters CL, Trounce IA.

J Mol Biol. 2006 Aug 18;361(3):493-505. Epub 2006 Jul 3.

PMID:
16854430

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