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Items: 1 to 20 of 97

1.

IL2/IL21 region polymorphism influences response to rituximab in systemic lupus erythematosus patients.

Márquez A, Dávila-Fajardo CL, Robledo G, Rubio JL, de Ramón Garrido E, García-Hernández FJ, González-León R, Ríos-Fernández R, Barrera JC, González-Escribano MF, García MT, Palma MJ, del Mar Ayala M, Ortego-Centeno N, Martín J.

Mol Biol Rep. 2013 Aug;40(8):4851-6. doi: 10.1007/s11033-013-2583-6. Epub 2013 May 5.

PMID:
23645042
2.

Confirmation of an association between rs6822844 at the Il2-Il21 region and multiple autoimmune diseases: evidence of a general susceptibility locus.

Maiti AK, Kim-Howard X, Viswanathan P, Guillén L, Rojas-Villarraga A, Deshmukh H, Direskeneli H, Saruhan-Direskeneli G, Cañas C, Tobön GJ, Sawalha AH, Cherñavsky AC, Anaya JM, Nath SK.

Arthritis Rheum. 2010 Feb;62(2):323-9. doi: 10.1002/art.27222.

3.

Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.

Hughes T, Kim-Howard X, Kelly JA, Kaufman KM, Langefeld CD, Ziegler J, Sanchez E, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Martín J, Brown EE, Vilá LM, Alarcón GS, James JA, Gilkeson GS, Moser KL, Gaffney PM, Merrill JT, Vyse TJ, Alarcón-Riquelme ME; BIOLUPUS Network., Nath SK, Harley JB, Sawalha AH.

Arthritis Rheum. 2011 Jun;63(6):1689-97. doi: 10.1002/art.30320.

4.

Association between -174 interleukin-6 gene polymorphism and biological response to rituximab in several systemic autoimmune diseases.

Robledo G, Dávila-Fajardo CL, Márquez A, Ortego-Centeno N, Callejas Rubio JL, de Ramón Garrido E, Sánchez-Román J, García-Hernández FJ, Ríos-Fernández R, González-Escribano MF, Camps García MT, Castillo Palma MJ, Ayala Mdel M, Martín J.

DNA Cell Biol. 2012 Sep;31(9):1486-91. doi: 10.1089/dna.2012.1684. Epub 2012 Jun 26.

PMID:
22734797
5.

Evaluation of the IL2/IL21, IL2RA and IL2RB genetic variants influence on the endogenous non-anterior uveitis genetic predisposition.

Cénit MC, Márquez A, Cordero-Coma M, Fonollosa A, Adán A, Martínez-Berriotxoa A, Llorenç V, Díaz Valle D, Blanco R, Cañal J, Díaz-Llopis M, García Serrano JL, de Ramón E, del Rio MJ, Begoña Gorroño-Echebarría M, Martín-Villa JM, Ortego-Centeno N, Martín J.

BMC Med Genet. 2013 May 15;14:52. doi: 10.1186/1471-2350-14-52.

6.

Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.

Hollis-Moffatt JE, Chen-Xu M, Topless R, Dalbeth N, Gow PJ, Harrison AA, Highton J, Jones PB, Nissen M, Smith MD, van Rij A, Jones GT, Stamp LK, Merriman TR.

Arthritis Res Ther. 2010;12(3):R116. doi: 10.1186/ar3053. Epub 2010 Jun 16.

7.

Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis.

Festen EA, Goyette P, Scott R, Annese V, Zhernakova A, Lian J, Lefèbvre C, Brant SR, Cho JH, Silverberg MS, Taylor KD, de Jong DJ, Stokkers PC, Mcgovern D, Palmieri O, Achkar JP, Xavier RJ, Daly MJ, Duerr RH, Wijmenga C, Weersma RK, Rioux JD.

Gut. 2009 Jun;58(6):799-804. doi: 10.1136/gut.2008.166918. Epub 2009 Feb 6.

8.

Association of the FCGR3A-158F/V gene polymorphism with the response to rituximab treatment in Spanish systemic autoimmune disease patients.

Robledo G, Márquez A, Dávila-Fajardo CL, Ortego-Centeno N, Rubio JL, Garrido Ede R, Sánchez-Román J, García-Hernández FJ, Ríos-Fernández R, González-Escribano MF, García MT, Palma MJ, Ayala Mdel M, Martín J.

DNA Cell Biol. 2012 Dec;31(12):1671-7. doi: 10.1089/dna.2012.1799. Epub 2012 Oct 17.

PMID:
23075294
9.

Autoimmune diseases association study with the KIAA1109-IL2-IL21 region in a Tunisian population.

Bouzid D, Fourati H, Amouri A, Marques I, Abida O, Tahri N, Penha-Gonçalves C, Masmoudi H.

Mol Biol Rep. 2014 Nov;41(11):7133-9. doi: 10.1007/s11033-014-3596-5. Epub 2014 Jul 19.

PMID:
25037274
10.

Analysis of IL2/IL21 gene variants in cholestatic liver diseases reveals an association with primary sclerosing cholangitis.

Stallhofer J, Denk GU, Glas J, Laubender RP, Göke B, Rust C, Brand S, Pusl T.

Digestion. 2011;84(1):29-35. doi: 10.1159/000321619. Epub 2011 Feb 8.

PMID:
21304239
11.

Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families.

Adamovic S, Amundsen SS, Lie BA, Gudjónsdóttir AH, Ascher H, Ek J, van Heel DA, Nilsson S, Sollid LM, Torinsson Naluai A.

Genes Immun. 2008 Jun;9(4):364-7. doi: 10.1038/gene.2008.27. Epub 2008 Apr 17.

PMID:
18418394
12.

Haplotype-based analysis of ulcerative colitis risk loci identifies both IL2 and IL21 as susceptibility genes in Han Chinese.

Shi J, Zhou L, Zhernakova A, Qian J, Zhu F, Sun G, Zhu L, Ma X, Dijkstra G, Wijmenga C, Faber KN, Lu X, Weersma RK.

Inflamm Bowel Dis. 2011 Dec;17(12):2472-9. doi: 10.1002/ibd.21652. Epub 2011 Jun 6.

PMID:
21648020
13.

Clinical outcomes and safety of rituximab treatment for patients with systemic lupus erythematosus (SLE) - results from a nationwide cohort in Germany (GRAID).

Witt M, Grunke M, Proft F, Baeuerle M, Aringer M, Burmester G, Chehab G, Fiehn C, Fischer-Betz R, Fleck M, Freivogel K, Haubitz M, Kötter I, Lovric S, Metzler C, Rubberth-Roth A, Schwarting A, Specker C, Tony HP, Unger L, Wassenberg S, Dörner T, Schulze-Koops H; German Registry of Autoimmune Diseases (GRAID) Investigators..

Lupus. 2013 Oct;22(11):1142-9. doi: 10.1177/0961203313503912.

PMID:
24057058
14.

Off-label use of rituximab in 196 patients with severe, refractory systemic autoimmune diseases.

Ramos-Casals M, García-Hernández FJ, de Ramón E, Callejas JL, Martínez-Berriotxoa A, Pallarés L, Caminal-Montero L, Selva-O'Callaghan A, Oristrell J, Hidalgo C, Pérez-Alvarez R, Micó ML, Medrano F, Gómez de la Torre R, Díaz-Lagares C, Camps M, Ortego N, Sánchez-Román J; BIOGEAS Study Group..

Clin Exp Rheumatol. 2010 Jul-Aug;28(4):468-76. Epub 2010 Aug 30.

PMID:
20525449
15.

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.

Glas J, Stallhofer J, Ripke S, Wetzke M, Pfennig S, Klein W, Epplen JT, Griga T, Schiemann U, Lacher M, Koletzko S, Folwaczny M, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2009 Jul;104(7):1737-44. doi: 10.1038/ajg.2009.163. Epub 2009 May 19.

PMID:
19455118
16.

Role of the rs6822844 gene polymorphism at the IL2-IL21 region in biopsy-proven giant cell arteritis.

Rodríguez-Rodríguez L, Castañeda S, Vázquez-Rodríguez TR, Morado IC, Gómez-Vaquero C, Marí-Alfonso B, Miranda-Filloy JA, Narvaez J, Ortego-Centeno N, Vicente EF, Blanco R, Amigo-Diaz E, Fernández-Gutiérrez B, Martin J, González-Gay MA.

Clin Exp Rheumatol. 2011 Jan-Feb;29(1 Suppl 64):S12-6. Epub 2011 May 11.

PMID:
21269573
17.

Novel association of the interleukin 2-interleukin 21 region with inflammatory bowel disease.

Márquez A, Orozco G, Martínez A, Palomino-Morales R, Fernández-Arquero M, Mendoza JL, Taxonera C, Díaz-Rubio M, Gómez-García M, Nieto A, López-Nevot MA, de la Concha EG, Martín J, Urcelay E.

Am J Gastroenterol. 2009 Aug;104(8):1968-75. doi: 10.1038/ajg.2009.224. Epub 2009 May 26.

PMID:
19471255
18.

Association of rs6822844 within the KIAA1109/TENR/IL2/IL21 locus with rheumatoid arthritis in the Algerian population.

Louahchi S, Allam I, Raaf N, Berkani L, Boucharef A, Abdessemed A, Khaldoun N, Bahaz N, Ladjouze-Rezig A, Nebbab A, Ghaffor M, Djidjik R.

HLA. 2016 Mar;87(3):160-4. doi: 10.1111/tan.12757. Epub 2016 Feb 24.

PMID:
26917059
19.

CTLA-4 gene polymorphism of exon 1(+49 A/G) in Turkish systemic lupus erythematosus patients.

Ulker M, Yazisiz V, Sallakci N, Avci AB, Sanlioglu S, Yegin O, Terzioglu E.

Int J Immunogenet. 2009 Aug;36(4):245-50. doi: 10.1111/j.1744-313X.2009.00856.x.

PMID:
19602000
20.

Multiple sclerosis association study with the TENR-IL2-IL21 region in a Spanish population.

Fedetz M, Ndagire D, Fernandez O, Leyva L, Guerrero M, Arnal C, Lucas M, Izquierdo G, Delgado C, Alcina A, Matesanz F.

Tissue Antigens. 2009 Sep;74(3):244-7. doi: 10.1111/j.1399-0039.2009.01298.x. Epub 2009 Jun 11.

PMID:
19523143

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