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Items: 1 to 20 of 189

1.

MicroRNA-21 activates hepatic stellate cells via PTEN/Akt signaling.

Wei J, Feng L, Li Z, Xu G, Fan X.

Biomed Pharmacother. 2013 Jun;67(5):387-92. doi: 10.1016/j.biopha.2013.03.014. Epub 2013 Mar 30.

PMID:
23643356
2.

Hepatic stellate cell is activated by microRNA-181b via PTEN/Akt pathway.

Zheng J, Wu C, Xu Z, Xia P, Dong P, Chen B, Yu F.

Mol Cell Biochem. 2015 Jan;398(1-2):1-9. doi: 10.1007/s11010-014-2199-8. Epub 2014 Aug 23.

PMID:
25148875
3.

Up-regulation of miR-200b in biliary atresia patients accelerates proliferation and migration of hepatic stallate cells by activating PI3K/Akt signaling.

Xiao Y, Wang J, Chen Y, Zhou K, Wen J, Wang Y, Zhou Y, Pan W, Cai W.

Cell Signal. 2014 May;26(5):925-32. doi: 10.1016/j.cellsig.2014.01.003. Epub 2014 Jan 8.

PMID:
24412919
4.

Profibrotic effect of miR-33a with Akt activation in hepatic stellate cells.

Li ZJ, Ou-Yang PH, Han XP.

Cell Signal. 2014 Jan;26(1):141-8. doi: 10.1016/j.cellsig.2013.09.018. Epub 2013 Oct 4.

PMID:
24100264
5.

Upregulation of microRNA-126 in hepatic stellate cells may affect pathogenesis of liver fibrosis through the NF-κB pathway.

Feng X, Tan W, Cheng S, Wang H, Ye S, Yu C, He Y, Zeng J, Cen J, Hu J, Zheng R, Zhou Y.

DNA Cell Biol. 2015 Jul;34(7):470-80. doi: 10.1089/dna.2014.2760. Epub 2015 May 14.

PMID:
25974152
6.

microRNA-21 mediates epithelial-mesenchymal transition of human hepatocytes via PTEN/Akt pathway.

Liu Z, Wang J, Guo C, Fan X.

Biomed Pharmacother. 2015 Feb;69:24-8. doi: 10.1016/j.biopha.2014.10.028. Epub 2014 Nov 6.

PMID:
25661333
7.

MicroRNA-29a Alleviates Bile Duct Ligation Exacerbation of Hepatic Fibrosis in Mice through Epigenetic Control of Methyltransferases.

Yang YL, Wang FS, Li SC, Tiao MM, Huang YH.

Int J Mol Sci. 2017 Jan 18;18(1). pii: E192. doi: 10.3390/ijms18010192.

8.

Identification of a Novel lincRNA-p21-miR-181b-PTEN Signaling Cascade in Liver Fibrosis.

Yu F, Lu Z, Chen B, Dong P, Zheng J.

Mediators Inflamm. 2016;2016:9856538. doi: 10.1155/2016/9856538. Epub 2016 Aug 16.

9.

Suppressive effect of microRNA-29b on hepatic stellate cell activation and its crosstalk with TGF-β1/Smad3.

Liang C, Bu S, Fan X.

Cell Biochem Funct. 2016 Jul;34(5):326-33. doi: 10.1002/cbf.3193. Epub 2016 Jun 7.

10.

Curcumin up-regulates phosphatase and tensin homologue deleted on chromosome 10 through microRNA-mediated control of DNA methylation--a novel mechanism suppressing liver fibrosis.

Zheng J, Wu C, Lin Z, Guo Y, Shi L, Dong P, Lu Z, Gao S, Liao Y, Chen B, Yu F.

FEBS J. 2014 Jan;281(1):88-103. doi: 10.1111/febs.12574. Epub 2013 Nov 5.

11.

miR-222 overexpression may contribute to liver fibrosis in biliary atresia by targeting PPP2R2A.

Dong R, Zheng Y, Chen G, Zhao R, Zhou Z, Zheng S.

J Pediatr Gastroenterol Nutr. 2015 Jan;60(1):84-90. doi: 10.1097/MPG.0000000000000573.

PMID:
25238119
12.

The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway.

Yu DK, Zhang CX, Zhao SS, Zhang SH, Zhang H, Cai SY, Shao RG, He HW.

Acta Pharmacol Sin. 2015 Apr;36(4):473-82. doi: 10.1038/aps.2014.155. Epub 2015 Mar 16.

13.

TGFβ-stimulated microRNA-21 utilizes PTEN to orchestrate AKT/mTORC1 signaling for mesangial cell hypertrophy and matrix expansion.

Dey N, Ghosh-Choudhury N, Kasinath BS, Choudhury GG.

PLoS One. 2012;7(8):e42316. doi: 10.1371/journal.pone.0042316. Epub 2012 Aug 3.

14.

MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis.

Ogawa T, Enomoto M, Fujii H, Sekiya Y, Yoshizato K, Ikeda K, Kawada N.

Gut. 2012 Nov;61(11):1600-9. Epub 2012 Jan 20.

PMID:
22267590
15.

HOTAIR Epigenetically Modulates PTEN Expression via MicroRNA-29b: A Novel Mechanism in Regulation of Liver Fibrosis.

Yu F, Chen B, Dong P, Zheng J.

Mol Ther. 2017 Jan 4;25(1):205-217. doi: 10.1016/j.ymthe.2016.10.015. Epub 2017 Jan 4.

PMID:
28129115
16.

The Epigenetically-Regulated microRNA-378a Targets TGF-β2 in TGF-β1-Treated Hepatic Stellate Cells.

Yu F, Yang J, Huang K, Pan X, Chen B, Dong P, Zheng J.

Cell Physiol Biochem. 2016;40(1-2):183-194. Epub 2016 Nov 18.

17.

Inhibitory effects of microRNA 19b in hepatic stellate cell-mediated fibrogenesis.

Lakner AM, Steuerwald NM, Walling TL, Ghosh S, Li T, McKillop IH, Russo MW, Bonkovsky HL, Schrum LW.

Hepatology. 2012 Jul;56(1):300-10. doi: 10.1002/hep.25613. Epub 2012 Jun 18.

18.

The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression.

Reif S, Lang A, Lindquist JN, Yata Y, Gabele E, Scanga A, Brenner DA, Rippe RA.

J Biol Chem. 2003 Mar 7;278(10):8083-90. Epub 2002 Dec 26.

19.

Suppression of hepatic stellate cell activation by microRNA-29b.

Sekiya Y, Ogawa T, Yoshizato K, Ikeda K, Kawada N.

Biochem Biophys Res Commun. 2011 Aug 19;412(1):74-9. doi: 10.1016/j.bbrc.2011.07.041. Epub 2011 Jul 21.

PMID:
21798245
20.

Hesperitin derivative-11 suppress hepatic stellate cell activation and proliferation by targeting PTEN/AKT pathway.

Li WX, Chen X, Yang Y, Huang HM, Li HD, Huang C, Meng XM, Li J.

Toxicology. 2017 Apr 15;381:75-86. doi: 10.1016/j.tox.2016.11.004. Epub 2016 Nov 3.

PMID:
27818223

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