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Items: 1 to 20 of 108

1.

Cardioprotective mechanism of diazoxide involves the inhibition of succinate dehydrogenase.

Anastacio MM, Kanter EM, Makepeace C, Keith AD, Zhang H, Schuessler RB, Nichols CG, Lawton JS.

Ann Thorac Surg. 2013 Jun;95(6):2042-50. doi: 10.1016/j.athoracsur.2013.03.035. Epub 2013 May 1.

2.

Diazoxide maintenance of myocyte volume and contractility during stress: evidence for a non-sarcolemmal K(ATP) channel location.

Sellitto AD, Maffit SK, Al-Dadah AS, Zhang H, Schuessler RB, Nichols CG, Lawton JS.

J Thorac Cardiovasc Surg. 2010 Nov;140(5):1153-9. doi: 10.1016/j.jtcvs.2010.07.047.

3.

Hyperkalemic cardioplegia-induced myocyte swelling and contractile dysfunction: prevention by diazoxide.

Mizutani S, Al-Dadah AS, Bloch JB, Prasad SM, Diodato MD, Schuessler RB, Damiano RJ Jr, Lawton JS.

Ann Thorac Surg. 2006 Jan;81(1):154-9.

PMID:
16368355
4.

Myocyte volume and function in response to osmotic stress: observations in the presence of an adenosine triphosphate-sensitive potassium channel opener.

Mizutani S, Prasad SM, Sellitto AD, Schuessler RB, Damiano RJ Jr, Lawton JS.

Circulation. 2005 Aug 30;112(9 Suppl):I219-23.

5.

Cardioprotective benefits of adenosine triphosphate-sensitive potassium channel opener diazoxide are lost with administration after the onset of stress in mouse and human myocytes.

Janjua MB, Makepeace CM, Anastacio MM, Schuessler RB, Nichols CG, Lawton JS.

J Am Coll Surg. 2014 Oct;219(4):803-13. doi: 10.1016/j.jamcollsurg.2014.05.010. Epub 2014 Jun 3.

6.

Adenosine Triphosphate-Sensitive Potassium Channel Kir Subunits Implicated in Cardioprotection by Diazoxide.

Henn MC, Janjua MB, Kanter EM, Makepeace CM, Schuessler RB, Nichols CG, Lawton JS.

J Am Heart Assoc. 2015 Aug 24;4(8):e002016. doi: 10.1161/JAHA.115.002016.

7.

Maintenance of myocyte volume homeostasis during stress by diazoxide is cardioprotective.

Al-Dadah AS, Voeller RK, Schuessler RB, Damiano RJ Jr, Lawton JS.

Ann Thorac Surg. 2007 Sep;84(3):857-62.

PMID:
17720390
8.

Role of the sarcolemmal adenosine triphosphate-sensitive potassium channel in hyperkalemic cardioplegia-induced myocyte swelling and reduced contractility.

Prasad SM, Al-Dadah AS, Byrd GD, Flagg TP, Gomes J, Damiano RJ Jr, Nichols CG, Lawton JS.

Ann Thorac Surg. 2006 Jan;81(1):148-53.

PMID:
16368354
9.

Diazoxide Cardioprotection Is Independent of Adenosine Triphosphate-Sensitive Potassium Channel Kir6.1 Subunit in Response to Stress.

Henn MC, Janjua MB, Zhang H, Kanter EM, Makepeace CM, Schuessler RB, Nichols CG, Lawton JS.

J Am Coll Surg. 2015 Aug;221(2):319-25. doi: 10.1016/j.jamcollsurg.2015.02.014. Epub 2015 Feb 21.

10.

Inhibition of Succinate Dehydrogenase by Diazoxide Is Independent of the ATP-Sensitive Potassium Channel Subunit Sulfonylurea Type 1 Receptor.

Anastacio MM, Kanter EM, Keith AD, Schuessler RB, Nichols CG, Lawton JS.

J Am Coll Surg. 2013 Jun;216(6):1144-9. doi: 10.1016/j.jamcollsurg.2013.01.048. Epub 2013 Mar 25.

11.

Increased tolerance to stress in cardiac expressed gain-of-function of adenosine triphosphate-sensitive potassium channel subunit Kir6.1.

Henn MC, Janjua MB, Zhang H, Kanter EM, Makepeace CM, Schuessler RB, Nichols CG, Lawton JS.

J Surg Res. 2016 Dec;206(2):460-465. doi: 10.1016/j.jss.2016.08.043. Epub 2016 Aug 12.

PMID:
27884343
12.

Diazoxide maintains human myocyte volume homeostasis during stress.

Maffit SK, Sellitto AD, Al-Dadah AS, Schuessler RB, Damiano RJ Jr, Lawton JS.

J Am Heart Assoc. 2012 Apr;1(2). pii: jah3-e000778. doi: 10.1161/JAHA.112.000778. Epub 2012 Apr 24.

13.

An open sarcolemmal adenosine triphosphate-sensitive potassium channel is necessary for detrimental myocyte swelling secondary to stress.

Sellitto AD, Al-Dadah AS, Schuessler RB, Nichols CG, Lawton JS.

Circulation. 2011 Sep 13;124(11 Suppl):S70-4. doi: 10.1161/CIRCULATIONAHA.110.012039.

14.

The risk of myocardial stunning is decreased concentration-dependently by KATP channel activation with nicorandil before high K+ cardioplegia.

Sugimoto S, Iwashiro K, Monti F, Dawodu AA, Schiariti M, Puddu PE.

Int J Cardiol. 1995 Jan 27;48(1):11-25.

PMID:
7744533
15.

Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice.

Suzuki M, Saito T, Sato T, Tamagawa M, Miki T, Seino S, Nakaya H.

Circulation. 2003 Feb 11;107(5):682-5.

16.

Multiplicity of effectors of the cardioprotective agent, diazoxide.

Coetzee WA.

Pharmacol Ther. 2013 Nov;140(2):167-75. doi: 10.1016/j.pharmthera.2013.06.007. Epub 2013 Jun 19. Review.

17.

Relationship between mitochondrial matrix volume and cellular volume in response to stress and the role of ATP-sensitive potassium channel.

Anastacio MM, Kanter EM, Makepeace CM, Keith AD, Zhang H, Schuessler RB, Nichols CG, Lawton JS.

Circulation. 2013 Sep 10;128(11 Suppl 1):S130-5. doi: 10.1161/CIRCULATIONAHA.112.000128.

18.

Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels. Possible mechanism of cardioprotection.

Garlid KD, Paucek P, Yarov-Yarovoy V, Murray HN, Darbenzio RB, D'Alonzo AJ, Lodge NJ, Smith MA, Grover GJ.

Circ Res. 1997 Dec;81(6):1072-82.

19.

Opening of mitochondrial ATP-sensitive potassium channels enhances cardioplegic protection.

Toyoda Y, Levitsky S, McCully JD.

Ann Thorac Surg. 2001 Apr;71(4):1281-8; discussion 1288-9.

PMID:
11308175
20.

Integrated pharmacological preconditioning in combination with adenosine, a mitochondrial KATP channel opener and a nitric oxide donor.

Uchiyama Y, Otani H, Okada T, Uchiyama T, Ninomiya H, Kido M, Imamura H, Nakao S, Shingu K.

J Thorac Cardiovasc Surg. 2003 Jul;126(1):148-59.

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