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Items: 1 to 20 of 84

1.

Adjuvant host-directed therapy with types 3 and 5 but not type 4 phosphodiesterase inhibitors shortens the duration of tuberculosis treatment.

Maiga M, Ammerman NC, Maiga MC, Tounkara A, Siddiqui S, Polis M, Murphy R, Bishai WR.

J Infect Dis. 2013 Aug 1;208(3):512-9. doi: 10.1093/infdis/jit187. Epub 2013 May 2. Erratum in: J Infect Dis. 2015 Jan 15;211(2):333.

2.

Successful shortening of tuberculosis treatment using adjuvant host-directed therapy with FDA-approved phosphodiesterase inhibitors in the mouse model.

Maiga M, Agarwal N, Ammerman NC, Gupta R, Guo H, Maiga MC, Lun S, Bishai WR.

PLoS One. 2012;7(2):e30749. doi: 10.1371/journal.pone.0030749. Epub 2012 Feb 3.

3.

Pharmacokinetics and safety of ambrisentan in combination with sildenafil in healthy volunteers.

Spence R, Mandagere A, Dufton C, Venitz J.

J Clin Pharmacol. 2008 Dec;48(12):1451-9. doi: 10.1177/0091270008324180. Epub 2008 Oct 1.

PMID:
18832294
4.

Effects of protein kinase A and G inhibitors on hippocampal cholinergic markers expressions in rolipram- and sildenafil-induced spatial memory improvement.

Hosseini-Sharifabad A, Ghahremani MH, Sabzevari O, Naghdi N, Abdollahi M, Beyer C, Bollen E, Prickaerts J, Roghani A, Sharifzadeh M.

Pharmacol Biochem Behav. 2012 May;101(3):311-9. doi: 10.1016/j.pbb.2012.01.017. Epub 2012 Jan 28.

PMID:
22306745
5.

Effects of phosphodiesterase inhibitors on the contractile responses of isolated human seminal vesicle tissue to adrenergic stimulation.

Uckert S, Bazrafshan S, Sonnenberg JE, Kuczyk MA.

J Sex Med. 2009 Feb;6(2):408-14. doi: 10.1111/j.1743-6109.2008.01085.x. Epub 2008 Nov 17.

PMID:
19040619
6.

Effect of repeated doses of darunavir plus low-dose ritonavir on the pharmacokinetics of sildenafil in healthy male subjects: phase I randomized, open-label, two-way crossover study.

Sekar V, Lefebvre E, De Marez T, De Pauw M, De Paepe E, Vangeneugden T, Hoetelmans RM.

Clin Drug Investig. 2008;28(8):479-85.

PMID:
18598093
7.

Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis.

Lubamba B, Lecourt H, Lebacq J, Lebecque P, De Jonge H, Wallemacq P, Leal T.

Am J Respir Crit Care Med. 2008 Mar 1;177(5):506-15. Epub 2007 Nov 15.

PMID:
18006891
8.

Phosphodiesterase type 5 inhibitors in pulmonary arterial hypertension.

Montani D, Chaumais MC, Savale L, Natali D, Price LC, Jaïs X, Humbert M, Simonneau G, Sitbon O.

Adv Ther. 2009 Sep;26(9):813-25. doi: 10.1007/s12325-009-0064-z. Epub 2009 Sep 19. Review.

PMID:
19768639
9.

Adherence to initial PDE-5 inhibitor treatment: randomized open-label study comparing tadalafil once a day, tadalafil on demand, and sildenafil on demand in patients with erectile dysfunction.

Buvat J, Büttner H, Hatzimouratidis K, Vendeira PA, Moncada I, Boehmer M, Henneges C, Boess FG.

J Sex Med. 2013 Jun;10(6):1592-602. doi: 10.1111/jsm.12130. Epub 2013 Apr 2.

PMID:
23551622
10.

Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model.

Rosenthal IM, Zhang M, Williams KN, Peloquin CA, Tyagi S, Vernon AA, Bishai WR, Chaisson RE, Grosset JH, Nuermberger EL.

PLoS Med. 2007 Dec;4(12):e344.

11.

The effects of pummelo juice on pharmacokinetics of sildenafil in healthy adult male Jordanian volunteers.

Al-Ghazawi MA, Tutunji MS, AbuRuz SM.

Eur J Clin Pharmacol. 2010 Feb;66(2):159-63. doi: 10.1007/s00228-009-0738-0. Epub 2009 Oct 15.

PMID:
19830413
12.

Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury.

de Visser YP, Walther FJ, Laghmani el H, Boersma H, van der Laarse A, Wagenaar GT.

Respir Res. 2009 Apr 29;10:30. doi: 10.1186/1465-9921-10-30.

13.

The effect of selective phosphodiesterase inhibitors, alone and in combination, on a murine model of allergic asthma.

Clayton RA, Dick CA, Mackenzie A, Nagasawa M, Galbraith D, Hastings SF, MacKenzie SJ.

Respir Res. 2004 May 5;5:4.

14.

Intranasal microemulsion of sildenafil citrate: in vitro evaluation and in vivo pharmacokinetic study in rabbits.

Elshafeey AH, Bendas ER, Mohamed OH.

AAPS PharmSciTech. 2009;10(2):361-7. doi: 10.1208/s12249-009-9213-6. Epub 2009 Mar 31.

15.

Comparison of the effects of cilostazol and milrinone on cAMP-PDE activity, intracellular cAMP and calcium in the heart.

Shakur Y, Fong M, Hensley J, Cone J, Movsesian MA, Kambayashi J, Yoshitake M, Liu Y.

Cardiovasc Drugs Ther. 2002 Sep;16(5):417-27.

PMID:
12652111
16.

Roflumilast, a Type 4 Phosphodiesterase Inhibitor, Shows Promising Adjunctive, Host-Directed Therapeutic Activity in a Mouse Model of Tuberculosis.

Maiga MC, Ahidjo BA, Maiga M, Bishai WR.

Antimicrob Agents Chemother. 2015 Dec;59(12):7888-90. doi: 10.1128/AAC.02145-15. Epub 2015 Oct 5.

17.

Selective PDE inhibitors rolipram and sildenafil improve object retrieval performance in adult cynomolgus macaques.

Rutten K, Basile JL, Prickaerts J, Blokland A, Vivian JA.

Psychopharmacology (Berl). 2008 Mar;196(4):643-8. Epub 2007 Nov 23.

18.

Chronic inhibition of phosphodiesterase 5 does not prevent pressure-overload-induced right-ventricular remodelling.

Schäfer S, Ellinghaus P, Janssen W, Kramer F, Lustig K, Milting H, Kast R, Klein M.

Cardiovasc Res. 2009 Apr 1;82(1):30-9. doi: 10.1093/cvr/cvp002. Epub 2009 Jan 8.

PMID:
19131365
19.

Determination of mirodenafil and sildenafil in the plasma and corpus cavernous of SD male rats.

Lee SK, Kim Y, Kim TK, Im GJ, Lee BY, Kim DH, Jin C, Yoo HH.

J Pharm Biomed Anal. 2009 Feb 20;49(2):513-8. doi: 10.1016/j.jpba.2008.11.004. Epub 2008 Nov 13.

PMID:
19095395
20.

Intravenous sildenafil in the treatment of neonates with persistent pulmonary hypertension.

Steinhorn RH, Kinsella JP, Pierce C, Butrous G, Dilleen M, Oakes M, Wessel DL.

J Pediatr. 2009 Dec;155(6):841-847.e1. doi: 10.1016/j.jpeds.2009.06.012.

PMID:
19836028

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