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Items: 1 to 20 of 117

1.

Development of a novel redirected T-cell-based adoptive immunotherapy targeting human telomerase reverse transcriptase for adult T-cell leukemia.

Miyazaki Y, Fujiwara H, Asai H, Ochi F, Ochi T, Azuma T, Ishida T, Okamoto S, Mineno J, Kuzushima K, Shiku H, Yasukawa M.

Blood. 2013 Jun 13;121(24):4894-901. doi: 10.1182/blood-2012-11-465971. Epub 2013 May 2.

2.

Universal cytotoxic activity of a HTLV-1 Tax-specific T cell clone from an HLA-A*24:02⁺ patient with adult T-cell leukemia against a variety of HTLV-I-infected T-cells.

Tanaka Y, Yamazaki R, Terasako-Saito K, Nakasone H, Akahoshi Y, Nakano H, Ugai T, Wada H, Yamasaki R, Ishihara Y, Kawamura K, Sakamoto K, Ashizawa M, Sato M, Kimura S, Kikuchi M, Kako S, Kanda J, Tanihara A, Nishida J, Kanda Y.

Immunol Lett. 2014 Mar-Apr;158(1-2):120-5. doi: 10.1016/j.imlet.2013.12.016. Epub 2014 Jan 2.

PMID:
24389072
3.

Novel adoptive T-cell immunotherapy using a WT1-specific TCR vector encoding silencers for endogenous TCRs shows marked antileukemia reactivity and safety.

Ochi T, Fujiwara H, Okamoto S, An J, Nagai K, Shirakata T, Mineno J, Kuzushima K, Shiku H, Yasukawa M.

Blood. 2011 Aug 11;118(6):1495-503. doi: 10.1182/blood-2011-02-337089. Epub 2011 Jun 14.

4.

[Development of Tax-redirected T-cell immunotherapy using TCR gene transduction in patients with ATL].

Tanaka Y, Kanda Y.

Rinsho Ketsueki. 2015 Jul;56(7):815-24. doi: 10.11406/rinketsu.56.815. Japanese.

PMID:
26251144
5.

Cyclin-dependent kinaselike 5 is a novel target of immunotherapy in adult T-cell leukemia.

Kawahara M, Hori T, Matsubara Y, Okawa K, Uchiyama T.

J Immunother. 2007 Jul-Aug;30(5):499-505.

PMID:
17589290
6.

Antitumor effect of new multiple antigen peptide based on HLA-A0201-restricted CTL epitopes of human telomerase reverse transcriptase (hTERT).

Liao ZL, Tang XD, Lü MH, Wu YY, Cao YL, Fang DC, Yang SM, Guo H.

Cancer Sci. 2012 Nov;103(11):1920-8. doi: 10.1111/j.1349-7006.2012.02410.x. Epub 2012 Sep 28.

7.

Single-cell analysis of T-cell receptor repertoire of HTLV-1 Tax-specific cytotoxic T cells in allogeneic transplant recipients with adult T-cell leukemia/lymphoma.

Tanaka Y, Nakasone H, Yamazaki R, Sato K, Sato M, Terasako K, Kimura S, Okuda S, Kako S, Oshima K, Tanihara A, Nishida J, Yoshikawa T, Nakatsura T, Sugiyama H, Kanda Y.

Cancer Res. 2010 Aug 1;70(15):6181-92. doi: 10.1158/0008-5472.CAN-10-0678. Epub 2010 Jul 20.

8.

Identification of a novel HLA-A*24:02-restricted adenovirus serotype 11-specific CD8+ T-cell epitope for adoptive immunotherapy.

Imahashi N, Nishida T, Ito Y, Kawada J, Nakazawa Y, Toji S, Suzuki S, Terakura S, Kato T, Murata M, Naoe T.

Mol Immunol. 2013 Dec;56(4):399-405. doi: 10.1016/j.molimm.2013.05.232. Epub 2013 Aug 1.

PMID:
23911395
9.

Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice.

Verra NC, Jorritsma A, Weijer K, Ruizendaal JJ, Voordouw A, Weder P, Hooijberg E, Schumacher TN, Haanen JB, Spits H, Luiten RM.

Cancer Res. 2004 Mar 15;64(6):2153-61.

10.

Targeting human telomerase reverse transcriptase with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo.

Adotévi O, Mollier K, Neuveut C, Dosset M, Ravel P, Fridman WH, Tartour E, Charneau P, Wain-Hobson S, Langlade-Demoyen P.

Blood. 2010 Apr 15;115(15):3025-32. doi: 10.1182/blood-2009-11-253641. Epub 2010 Feb 3.

12.

Graft-versus-Tax response in adult T-cell leukemia patients after hematopoietic stem cell transplantation.

Harashima N, Kurihara K, Utsunomiya A, Tanosaki R, Hanabuchi S, Masuda M, Ohashi T, Fukui F, Hasegawa A, Masuda T, Takaue Y, Okamura J, Kannagi M.

Cancer Res. 2004 Jan 1;64(1):391-9.

13.

Recognition of a natural WT1 epitope by a modified WT1 peptide-specific T-cell receptor.

Tamanaka T, Oka Y, Fujiki F, Tsuboi A, Katsuhara A, Nakajima H, Hosen N, Nishida S, Lin YH, Tachino S, Akatsuka Y, Kuzushima K, Oji Y, Kumanogoh A, Sugiyama H.

Anticancer Res. 2012 Dec;32(12):5201-9.

PMID:
23225417
14.
15.

Interferon-gamma differentially regulates susceptibility of lung cancer cells to telomerase-specific cytotoxic T lymphocytes.

Tajima K, Ito Y, Demachi A, Nishida K, Akatsuka Y, Tsujimura K, Hida T, Morishima Y, Kuwano H, Mitsudomi T, Takahashi T, Kuzushima K.

Int J Cancer. 2004 Jun 20;110(3):403-12.

16.

Differential lysis of tumors by polyclonal T cell lines and T cell clones specific for hTERT.

Chen DY, Vance BA, Thompson LB, Domchek SM, Vonderheide RH.

Cancer Biol Ther. 2007 Dec;6(12):1991-6. Epub 2007 Sep 24.

PMID:
18087213
17.

Potential contribution of a novel Tax epitope-specific CD4+ T cells to graft-versus-Tax effect in adult T cell leukemia patients after allogeneic hematopoietic stem cell transplantation.

Tamai Y, Hasegawa A, Takamori A, Sasada A, Tanosaki R, Choi I, Utsunomiya A, Maeda Y, Yamano Y, Eto T, Koh KR, Nakamae H, Suehiro Y, Kato K, Takemoto S, Okamura J, Uike N, Kannagi M.

J Immunol. 2013 Apr 15;190(8):4382-92. doi: 10.4049/jimmunol.1202971. Epub 2013 Mar 8.

18.

Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes.

Tsuji T, Yasukawa M, Matsuzaki J, Ohkuri T, Chamoto K, Wakita D, Azuma T, Niiya H, Miyoshi H, Kuzushima K, Oka Y, Sugiyama H, Ikeda H, Nishimura T.

Blood. 2005 Jul 15;106(2):470-6. Epub 2005 Mar 24.

19.

In vitro quantification of the cytotoxic T lymphocyte response against human telomerase reverse transcriptase in breast cancer.

Amarnath SM, Dyer CE, Ramesh A, Iwuagwu O, Drew PJ, Greenman J.

Int J Oncol. 2004 Jul;25(1):211-7.

PMID:
15202008
20.

Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase.

Vonderheide RH, Anderson KS, Hahn WC, Butler MO, Schultze JL, Nadler LM.

Clin Cancer Res. 2001 Nov;7(11):3343-8.

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