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Neutralization of interleukin-1 beta attenuates silica-induced lung inflammation and fibrosis in C57BL/6 mice.

Guo J, Gu N, Chen J, Shi T, Zhou Y, Rong Y, Zhou T, Yang W, Cui X, Chen W.

Arch Toxicol. 2013 Nov;87(11):1963-73. doi: 10.1007/s00204-013-1063-z. Epub 2013 May 3.


[The role of interleukin-1β on the pulmonary fibrosis in mice exposed to crystalline silica].

Guo JL, Cui XQ, Rong Y, Zhou T, Zhou Y, Zhang ZH, Gu NL, Chen WH.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2013 Jul;31(7):481-6. Chinese.


Neutralization of interleukin-17A delays progression of silica-induced lung inflammation and fibrosis in C57BL/6 mice.

Chen Y, Li C, Weng D, Song L, Tang W, Dai W, Yu Y, Liu F, Zhao M, Lu C, Chen J.

Toxicol Appl Pharmacol. 2014 Feb 15;275(1):62-72. doi: 10.1016/j.taap.2013.11.012. Epub 2013 Nov 26.


IL-6 receptor-mediated lung Th2 cytokine networking in silica-induced pulmonary fibrosis.

Tripathi SS, Mishra V, Shukla M, Verma M, Chaudhury BP, Kumar P, Chhabra JK, Pandey HP, Paul B.

Arch Toxicol. 2010 Dec;84(12):947-55. doi: 10.1007/s00204-010-0559-z. Epub 2010 May 20.


CD4+CD25+Foxp3+ regulatory T cells depletion may attenuate the development of silica-induced lung fibrosis in mice.

Liu F, Liu J, Weng D, Chen Y, Song L, He Q, Chen J.

PLoS One. 2010 Nov 3;5(11):e15404. doi: 10.1371/journal.pone.0015404.


Lung fibrosis induced by crystalline silica particles is uncoupled from lung inflammation in NMRI mice.

Rabolli V, Lo Re S, Uwambayinema F, Yakoub Y, Lison D, Huaux F.

Toxicol Lett. 2011 Jun 10;203(2):127-34. doi: 10.1016/j.toxlet.2011.03.009. Epub 2011 Mar 23.


P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica.

Monção-Ribeiro LC, Faffe DS, Santana PT, Vieira FS, da Graça CL, Marques-da-Silva C, Machado MN, Caruso-Neves C, Zin WA, Borojevic R, Takiya CM, Coutinho-Silva R.

PLoS One. 2014 Oct 13;9(10):e110185. doi: 10.1371/journal.pone.0110185. eCollection 2014.


Pulmonary overexpression of IL-10 augments lung fibrosis and Th2 responses induced by silica particles.

Barbarin V, Xing Z, Delos M, Lison D, Huaux F.

Am J Physiol Lung Cell Mol Physiol. 2005 May;288(5):L841-8. Epub 2004 Dec 17.


A profibrotic function of IL-12p40 in experimental pulmonary fibrosis.

Huaux F, Arras M, Tomasi D, Barbarin V, Delos M, Coutelier JP, Vink A, Phan SH, Renauld JC, Lison D.

J Immunol. 2002 Sep 1;169(5):2653-61.


Th17 can regulate silica-induced lung inflammation through an IL-1β-dependent mechanism.

Song L, Weng D, Dai W, Tang W, Chen S, Li C, Chen Y, Liu F, Chen J.

J Cell Mol Med. 2014 Sep;18(9):1773-84. doi: 10.1111/jcmm.12341. Epub 2014 Aug 5.


Bone marrow-derived mononuclear cell therapy attenuates silica-induced lung fibrosis.

Maron-Gutierrez T, Castiglione RC, Xisto DG, Oliveira MG, Cruz FF, Peçanha R, Carreira-Junior H, Ornellas DS, Moraes MO, Takiya CM, Rocco PR, Morales MM.

Eur Respir J. 2011 May;37(5):1217-25. doi: 10.1183/09031936.00205009. Epub 2010 Aug 6.


Use of tetrandrine to differentiate between mechanisms involved in silica-versus bleomycin-induced fibrosis.

Ma JY, Barger MW, Hubbs AF, Castranova V, Weber SL, Ma JK.

J Toxicol Environ Health A. 1999 Jun 25;57(4):247-66.


Baicalin Alleviates Silica-Induced Lung Inflammation and Fibrosis by Inhibiting the Th17 Response in C57BL/6 Mice.

Liu T, Dai W, Li C, Liu F, Chen Y, Weng D, Chen J.

J Nat Prod. 2015 Dec 24;78(12):3049-57. doi: 10.1021/acs.jnatprod.5b00868. Epub 2015 Nov 25.


[Changes of cell factor in bronchoalveolar lavage fluid in rats exposed to silica].

Zhang W, Wang R, Wang X, Zhou XB, Wang H, Zhang HD, Liu ZL.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2013 Nov;31(11):801-5. Chinese.


WNT/β-catenin signaling induces IL-1β expression by alveolar epithelial cells in pulmonary fibrosis.

Aumiller V, Balsara N, Wilhelm J, Günther A, Königshoff M.

Am J Respir Cell Mol Biol. 2013 Jul;49(1):96-104. doi: 10.1165/rcmb.2012-0524OC.


TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis.

Bonniaud P, Margetts PJ, Ask K, Flanders K, Gauldie J, Kolb M.

J Immunol. 2005 Oct 15;175(8):5390-5.


Hydrogen sulfide protects against bleomycin-induced pulmonary fibrosis in rats by inhibiting NF-κB expression and regulating Th1/Th2 balance.

Cao H, Zhou X, Zhang J, Huang X, Zhai Y, Zhang X, Chu L.

Toxicol Lett. 2014 Jan 30;224(3):387-94. doi: 10.1016/j.toxlet.2013.11.008. Epub 2013 Nov 20.


Protective effects of methyl palmitate against silica-induced pulmonary fibrosis in rats.

Sharawy MH, El-Agamy DS, Shalaby AA, Ammar el-SM.

Int Immunopharmacol. 2013 Jun;16(2):191-8. doi: 10.1016/j.intimp.2013.04.007. Epub 2013 Apr 18.


The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles.

Rabolli V, Badissi AA, Devosse R, Uwambayinema F, Yakoub Y, Palmai-Pallag M, Lebrun A, De Gussem V, Couillin I, Ryffel B, Marbaix E, Lison D, Huaux F.

Part Fibre Toxicol. 2014 Dec 13;11:69. doi: 10.1186/s12989-014-0069-x.


IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis.

Lo Re S, Dumoutier L, Couillin I, Van Vyve C, Yakoub Y, Uwambayinema F, Marien B, van den Brûle S, Van Snick J, Uyttenhove C, Ryffel B, Renauld JC, Lison D, Huaux F.

J Immunol. 2010 Jun 1;184(11):6367-77. doi: 10.4049/jimmunol.0900459. Epub 2010 Apr 26.

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