Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 104

1.

Puerarin stimulates proliferation and differentiation and protects against cell death in human osteoblastic MG-63 cells via ER-dependent MEK/ERK and PI3K/Akt activation.

Wang Y, Wang WL, Xie WL, Li LZ, Sun J, Sun WJ, Gong HY.

Phytomedicine. 2013 Jul 15;20(10):787-96. doi: 10.1016/j.phymed.2013.03.005. Epub 2013 Apr 29.

PMID:
23639192
2.

Puerarin concurrently stimulates osteoprotegerin and inhibits receptor activator of NF-κB ligand (RANKL) and interleukin-6 production in human osteoblastic MG-63 cells.

Wang Y, Yang C, Xie WL, Zhao YW, Li ZM, Sun WJ, Li LZ.

Phytomedicine. 2014 Jul-Aug;21(8-9):1032-6. doi: 10.1016/j.phymed.2014.04.012. Epub 2014 May 19.

PMID:
24854571
3.

LC, a novel estrone-rhein hybrid compound, promotes proliferation and differentiation and protects against cell death in human osteoblastic MG-63 cells.

Wang Y, Li LZ, Zhang YL, Sun WJ, Zhu YQ, Cui Y, Qi L.

Mol Cell Endocrinol. 2011 Sep 15;344(1-2):59-68. doi: 10.1016/j.mce.2011.06.027. Epub 2011 Jul 13.

PMID:
21767602
4.

Upregulation of osteoblastic differentiation marker mRNA expression in osteoblast-like UMR106 cells by puerarin and phytoestrogens from Pueraria mirifica.

Tiyasatkulkovit W, Charoenphandhu N, Wongdee K, Thongbunchoo J, Krishnamra N, Malaivijitnond S.

Phytomedicine. 2012 Oct 15;19(13):1147-55. doi: 10.1016/j.phymed.2012.07.010. Epub 2012 Aug 27.

PMID:
22951392
5.

Stimulatory effect of puerarin on bone formation through activation of PI3K/Akt pathway in rat calvaria osteoblasts.

Zhang Y, Zeng X, Zhang L, Zheng X.

Planta Med. 2007 Apr;73(4):341-7. Epub 2007 Apr 18.

PMID:
17443435
6.

Mechanism of phytoestrogen puerarin-mediated cytoprotection following oxidative injury: estrogen receptor-dependent up-regulation of PI3K/Akt and HO-1.

Hwang YP, Jeong HG.

Toxicol Appl Pharmacol. 2008 Dec 15;233(3):371-81. doi: 10.1016/j.taap.2008.09.006. Epub 2008 Sep 19.

PMID:
18845176
7.
8.

Puerarin protects differentiated PC12 cells from H₂O₂-induced apoptosis through the PI3K/Akt signalling pathway.

Zhang Q, Huang WD, Lv XY, Yang YM.

Cell Biol Int. 2012 May 1;36(5):419-26. doi: 10.1042/CBI20100900.

PMID:
22126839
9.

Puerarin stimulates osteoblasts differentiation and bone formation through estrogen receptor, p38 MAPK, and Wnt/β-catenin pathways.

Wang PP, Zhu XF, Yang L, Liang H, Feng SW, Zhang RH.

J Asian Nat Prod Res. 2012;14(9):897-905. doi: 10.1080/10286020.2012.702757. Epub 2012 Aug 23.

PMID:
22917468
10.

LC, a novel estrone-rhein hybrid compound, concurrently stimulates osteoprotegerin and inhibits receptor activator of NF-κB ligand (RANKL) and interleukin-6 production by human osteoblastic cells.

Wang Y, Li LZ, Zhang YL, Zhu YQ, Wu J, Sun WJ.

Mol Cell Endocrinol. 2011 Apr 30;337(1-2):43-51. doi: 10.1016/j.mce.2011.01.018. Epub 2011 Feb 2.

PMID:
21291955
11.

Puerarin enhances proliferation and osteoblastic differentiation of human bone marrow stromal cells via a nitric oxide/cyclic guanosine monophosphate signaling pathway.

Lv H, Che T, Tang X, Liu L, Cheng J.

Mol Med Rep. 2015 Aug;12(2):2283-90. doi: 10.3892/mmr.2015.3647. Epub 2015 Apr 20.

PMID:
25892538
12.

The proliferation, differentiation, and mineralization effects of puerarin on osteoblasts in vitro.

Wang C, Meng MX, Tang XL, Chen KM, Zhang L, Liu WN, Zhao YY.

Chin J Nat Med. 2014 Jun;12(6):436-42. doi: 10.1016/S1875-5364(14)60068-6.

PMID:
24969524
13.

Puerarin attenuates glucocorticoid-induced apoptosis of hFOB1.19 cells through the JNK- and Akt-mediated mitochondrial apoptotic pathways.

Yu D, Mu S, Zhao D, Wang G, Chen Z, Ren H, Fu Q.

Int J Mol Med. 2015 Aug;36(2):345-54. doi: 10.3892/ijmm.2015.2258. Epub 2015 Jun 23.

14.

Puerarin attenuates calcification of vascular smooth muscle cells.

Lu Q, Xiang DX, Yuan HY, Xiao Y, Yuan LQ, Li HB.

Am J Chin Med. 2014;42(2):337-47. doi: 10.1142/S0192415X14500220.

PMID:
24707866
15.

In vitro and in vivo effects of puerarin on promotion of osteoblast bone formation.

Zhang MY, Qiang H, Yang HQ, Dang XQ, Wang KZ.

Chin J Integr Med. 2012 Apr;18(4):276-82. doi: 10.1007/s11655-012-1056-4. Epub 2012 Mar 30.

PMID:
22457138
16.

N-cadherin negatively regulates osteoblast proliferation and survival by antagonizing Wnt, ERK and PI3K/Akt signalling.

Haÿ E, Nouraud A, Marie PJ.

PLoS One. 2009 Dec 14;4(12):e8284. doi: 10.1371/journal.pone.0008284.

17.

Activation of the PI3K/Akt signaling pathway through P2Y₂ receptors by extracellular ATP is involved in osteoblastic cell proliferation.

Katz S, Ayala V, Santillán G, Boland R.

Arch Biochem Biophys. 2011 Sep 15;513(2):144-52. doi: 10.1016/j.abb.2011.06.013. Epub 2011 Jul 6.

PMID:
21763267
18.

PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cells.

Aksamitiene E, Kholodenko BN, Kolch W, Hoek JB, Kiyatkin A.

Cell Signal. 2010 Sep;22(9):1369-78. doi: 10.1016/j.cellsig.2010.05.006. Epub 2010 May 12.

19.

Involvement of activation of PI3K/Akt pathway in the protective effects of puerarin against MPP+-induced human neuroblastoma SH-SY5Y cell death.

Zhu G, Wang X, Wu S, Li Q.

Neurochem Int. 2012 Mar;60(4):400-8. doi: 10.1016/j.neuint.2012.01.003. Epub 2012 Jan 12.

PMID:
22265823
20.

Icariin induces osteoblast proliferation, differentiation and mineralization through estrogen receptor-mediated ERK and JNK signal activation.

Song L, Zhao J, Zhang X, Li H, Zhou Y.

Eur J Pharmacol. 2013 Aug 15;714(1-3):15-22. doi: 10.1016/j.ejphar.2013.05.039. Epub 2013 Jun 11.

PMID:
23764463

Supplemental Content

Support Center